Indole alkaloid from the plant Arundo donax, Gramineae. Inhibitor of acetylcholinesterase and butyrylcholinesterase. a competitive serotonin antagonist
Type : Alkaloid, Natural, Not A\/B H target, Indole
Chemical_Nomenclature : 1-(1H-indol-3-yl)-N,N-dimethylmethanamine
Canonical SMILES : CN(C)CC1=CNC2=CC=CC=C21
InChI : InChI=1S\/C11H14N2\/c1-13(2)8-9-7-12-11-6-4-3-5-10(9)11\/h3-7,12H,8H2,1-2H3
InChIKey : OCDGBSUVYYVKQZ-UHFFFAOYSA-N
Other name(s) : Donaxine, Donaxin, Gramin, Indolalkylamine der., beta-Dimethylaminomethylindole, b-(Dimethylaminomethyl)indole, 3-[(Dimethylamino)methyl]indole, Indol-3-ylmethyldimethylamine, 3-(Dimethylaminomethyl)indole
MW : 174
Formula : C11H14N2
CAS_number : 87-52-5
PubChem : 6890
UniChem : OCDGBSUVYYVKQZ-UHFFFAOYSA-N
Wikipedia : Gramine
Title : Differential inhibition of [3H]-oxotremorine-M and [3H]-quinuclinidyl benzilate binding to muscarinic receptors in rat brain membranes with acetylcholinesterase inhibitors - Lockhart_2001_Naunyn.Schmiedebergs.Arch.Pharmacol_363_429 |
Author(s) : Lockhart B , Closier M , Howard K , Steward C , Lestage P |
Ref : Naunyn Schmiedebergs Arch Pharmacol , 363 :429 , 2001 |
PubMedID: 11330337 |