KT-1-147
General
Type : Pyrazole, Pyridine, Carboxamide
Chemical_Nomenclature : 3-methyl-1-(2-phenylethyl)-N-[(pyridin-3-yl)methyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
Canonical SMILES : CC2=N[N](CCC1=CC=CC=C1)C3=C2C=C(C=N3)C(=O)NCC4=CN=CC=C4
InChI : InChI=1S\/C22H21N5O\/c1-16-20-12-19(22(28)25-14-18-8-5-10-23-13-18)15-24-21(20)27(26-16)11-9-17-6-3-2-4-7-17\/h2-8,10,12-13,15H,9,11,14H2,1H3,(H,25,28)
InChIKey : XLVHZGUUORIPAP-UHFFFAOYSA-N
Other name(s) : A1CQS || A1CQV
Target
Families : KT-1-147 ligand of proteins in family
S9N_PPCE_Peptidase_S9
Structure :
9Q5Z
Protein :
human-PREP
References (1)
| Title : Structure-Guided Optimization of 4-Chloro-Pyrazolopyridine Analogs for Covalent PREP Inhibition - Thakur_2026_J.Med.Chem__ |
| Author(s) : Thakur K , Fucci I , Pandian J , Suazo KF , Monteiro DCF , Yoo E |
| Ref : Journal of Medicinal Chemistry , : , 2026 |
| Abstract : |
| PubMedSearch : Thakur_2026_J.Med.Chem__ |
| PubMedID: 41512187 |
| Gene_locus related to this paper: human-PREPL |