KT-2-59
General
Type : Pyrazole, Pyridine, Carboxamide
Chemical_Nomenclature : 1,3-dimethyl-N-[(pyridin-3-yl)methyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
Canonical SMILES : C[N]1N=C(C)C2=C1N=CC(=C2Cl)C(=O)NCC3=CC=CN=C3
InChI : InChI=1S\/C15H14ClN5O\/c1-9-12-13(16)11(8-18-14(12)21(2)20-9)15(22)19-7-10-4-3-5-17-6-10\/h3-6,8H,7H2,1-2H3,(H,19,22)
InChIKey : KVCCRSZXQPYJDM-UHFFFAOYSA-N
Other name(s) : A1CQV
Target
Families : KT-2-59 ligand of proteins in family
S9N_PPCE_Peptidase_S9
Structure :
9Q64
Protein :
human-PREP
References (2)
| Title : Structure-Guided Optimization of 4-Chloro-Pyrazolopyridine Analogs for Covalent PREP Inhibition - Thakur_2026_J.Med.Chem__ |
| Author(s) : Thakur K , Fucci I , Pandian J , Suazo KF , Monteiro DCF , Yoo E |
| Ref : Journal of Medicinal Chemistry , : , 2026 |
| Abstract : |
| PubMedSearch : Thakur_2026_J.Med.Chem__ |
| PubMedID: 41512187 |
| Gene_locus related to this paper: human-PREPL |
| Title : Structure-Guided Optimization of 4-Chloro-Pyrazolopyridine Analogs for Covalent PREP Inhibition - Thakur_2026_J.Med.Chem__ |
| Author(s) : Thakur K , Fucci I , Pandian J , Suazo KF , Monteiro DCF , Yoo E |
| Ref : Journal of Medicinal Chemistry , : , 2026 |
| Abstract : |
| PubMedSearch : Thakur_2026_J.Med.Chem__ |
| PubMedID: 41512187 |
| Gene_locus related to this paper: human-PREPL |