MFPCh

CID:102332; 2797-10-6; Methyl fluorophosphoryl choline iodide; 2-Trimethylammoniummethyl methylphosphonofluoridate iodide 311.070 g/mol C6H16FINO2P

General

Type : Tammelin ester, Organophosphate, Choline ester

Chemical_Nomenclature : 2-[fluoro(methyl)phosphoryl]oxyethyl-trimethylazanium

Canonical SMILES : C[N+](C)(C)CCOP(=O)(C)F

InChI : InChI=1S\/C6H16FNO2P\/c1-8(2,3)5-6-10-11(4,7)9\/h5-6H2,1-4H3\/q+1

InChIKey : OKNSDXKIPFDADW-UHFFFAOYSA-N

Other name(s) : methylfluorophosphonylcholine  ||  BRN 1780107  ||  (2-Hydroxyethyl)trimethylammonium ester with methylphosphonofluoridate  ||  Ammonium, (2-Hydroxyethyl)trimethyl, ester with methylphosphonofluoridate  ||  Methyl-fluoro-phosphorylcholine


MW : 184.17

Formula : C6H16FNO2P+

CAS_number : 44991-89-1

PubChem : 39430

UniChem : OKNSDXKIPFDADW-UHFFFAOYSA-N

Target

Families : MFPCh ligand of proteins in family
ACHE

References (4)

Title : Nontargeted High-Resolution Mass Spectrometric Workflow for the Detection of Butyrylcholinesterase-Derived Adducts with Organophosphorus Toxicants and Structural Characterization of Their Phosphyl Moiety after In-Source Fragmentation - John_2022_Anal.Chem__
Author(s) : John H , Dentzel M , Siegert M , Thiermann H
Ref : Analytical Chemistry , : , 2022
Abstract :
PubMedSearch : John_2022_Anal.Chem__
PubMedID: 35041786

Title : Reactivation and aging kinetics of human acetylcholinesterase inhibited by organophosphonylcholines - Worek_2004_Arch.Toxicol_78_212
Author(s) : Worek F , Thiermann H , Szinicz L
Ref : Archives of Toxicology , 78 :212 , 2004
Abstract :
PubMedSearch : Worek_2004_Arch.Toxicol_78_212
PubMedID: 14647978

Title : Inhibition of cholinesterase with methylfluorophosphorylcholine and carbocholine: spontaneous return of activity - Fredriksson_1960_Biochem.Pharmacol_3_184
Author(s) : Fredriksson T , Tibbling G
Ref : Biochemical Pharmacology , 3 :184 , 1960
Abstract :
PubMedSearch : Fredriksson_1960_Biochem.Pharmacol_3_184
PubMedID: 13824696

Title : Further studies on fluorophosphorylcholines. Pharmacological properties of two new analogues -
Author(s) : Fredriksson T
Ref : Archives Internationales de Pharmacodynamie et de Therapie , 115 :474 , 1958
PubMedID: 13572115