MFPCh
CID:102332; 2797-10-6; Methyl fluorophosphoryl choline iodide; 2-Trimethylammoniummethyl methylphosphonofluoridate iodide 311.070 g/mol C6H16FINO2P
General
Type : Tammelin ester, Organophosphate, Choline ester
Chemical_Nomenclature : 2-[fluoro(methyl)phosphoryl]oxyethyl-trimethylazanium
Canonical SMILES : C[N+](C)(C)CCOP(=O)(C)F
InChI : InChI=1S\/C6H16FNO2P\/c1-8(2,3)5-6-10-11(4,7)9\/h5-6H2,1-4H3\/q+1
InChIKey : OKNSDXKIPFDADW-UHFFFAOYSA-N
Other name(s) : methylfluorophosphonylcholine || BRN 1780107 || (2-Hydroxyethyl)trimethylammonium ester with methylphosphonofluoridate || Ammonium, (2-Hydroxyethyl)trimethyl, ester with methylphosphonofluoridate || Methyl-fluoro-phosphorylcholine
MW : 184.17
Formula : C6H16FNO2P+
CAS_number : 44991-89-1
PubChem : 39430
UniChem : OKNSDXKIPFDADW-UHFFFAOYSA-N
Target
Families : MFPCh ligand of proteins in family
ACHE
References (4)
| Title : Nontargeted High-Resolution Mass Spectrometric Workflow for the Detection of Butyrylcholinesterase-Derived Adducts with Organophosphorus Toxicants and Structural Characterization of Their Phosphyl Moiety after In-Source Fragmentation - John_2022_Anal.Chem__ |
| Author(s) : John H , Dentzel M , Siegert M , Thiermann H |
| Ref : Analytical Chemistry , : , 2022 |
| Abstract : |
| PubMedSearch : John_2022_Anal.Chem__ |
| PubMedID: 35041786 |
| Title : Reactivation and aging kinetics of human acetylcholinesterase inhibited by organophosphonylcholines - Worek_2004_Arch.Toxicol_78_212 |
| Author(s) : Worek F , Thiermann H , Szinicz L |
| Ref : Archives of Toxicology , 78 :212 , 2004 |
| Abstract : |
| PubMedSearch : Worek_2004_Arch.Toxicol_78_212 |
| PubMedID: 14647978 |
| Title : Inhibition of cholinesterase with methylfluorophosphorylcholine and carbocholine: spontaneous return of activity - Fredriksson_1960_Biochem.Pharmacol_3_184 |
| Author(s) : Fredriksson T , Tibbling G |
| Ref : Biochemical Pharmacology , 3 :184 , 1960 |
| Abstract : |
| PubMedSearch : Fredriksson_1960_Biochem.Pharmacol_3_184 |
| PubMedID: 13824696 |
| Title : Further studies on fluorophosphorylcholines. Pharmacological properties of two new analogues - |
| Author(s) : Fredriksson T |
| Ref : Archives Internationales de Pharmacodynamie et de Therapie , 115 :474 , 1958 |
| PubMedID: 13572115 |