Full name : Szinicz Ladislaus
First name : Ladislaus
Mail : Institute of Pharmacology & Toxicology, FAF Medical Academy, D-85748 Garching
Zip Code :
City :
Country : Germany
Email :
Phone : 49-89-315-5063
Fax : 49-89-375-5063
Website :
Directory :
Comment
| Title : Obituary: In memory of Elsa Reiner - Eyer_2011_Toxicol.Lett_206_1 |
| Author(s) : Eyer P , Szinicz L |
| Ref : Toxicol Lett , 206 :1 , 2011 |
| Abstract : |
| PubMedSearch : Eyer_2011_Toxicol.Lett_206_1 |
| PubMedID: |
| Title : Enzyme-kinetic investigation of different sarin analogues reacting with human acetylcholinesterase and butyrylcholinesterase - Bartling_2007_Toxicology_233_166 |
| Author(s) : Bartling A , Worek F , Szinicz L , Thiermann H |
| Ref : Toxicology , 233 :166 , 2007 |
| Abstract : |
| PubMedSearch : Bartling_2007_Toxicology_233_166 |
| PubMedID: 16904809 |
| Title : Reevaluation of indirect field stimulation technique to demonstrate oxime effectiveness in OP-poisoning in muscles in vitro - Seeger_2007_Toxicology_233_209 |
| Author(s) : Seeger T , Worek F , Szinicz L , Thiermann H |
| Ref : Toxicology , 233 :209 , 2007 |
| Abstract : |
| PubMedSearch : Seeger_2007_Toxicology_233_209 |
| PubMedID: 17250944 |
| Title : Development of antidotes: problems and strategies - Szinicz_2007_Toxicology_233_23 |
| Author(s) : Szinicz L , Worek F , Thiermann H , Kehe K , Eckert S , Eyer P |
| Ref : Toxicology , 233 :23 , 2007 |
| Abstract : |
| PubMedSearch : Szinicz_2007_Toxicology_233_23 |
| PubMedID: 16949190 |
| Title : Lessons to be learnt from organophosphorus pesticide poisoning for the treatment of nerve agent poisoning - Thiermann_2007_Toxicology_233_145 |
| Author(s) : Thiermann H , Szinicz L , Eyer P , Felgenhauer N , Zilker T , Worek F |
| Ref : Toxicology , 233 :145 , 2007 |
| Abstract : |
| PubMedSearch : Thiermann_2007_Toxicology_233_145 |
| PubMedID: 17161895 |
| Title : Recent advances in evaluation of oxime efficacy in nerve agent poisoning by in vitro analysis - Worek_2007_Toxicol.Appl.Pharmacol_219_226 |
| Author(s) : Worek F , Eyer P , Aurbek N , Szinicz L , Thiermann H |
| Ref : Toxicol Appl Pharmacol , 219 :226 , 2007 |
| Abstract : |
| PubMedSearch : Worek_2007_Toxicol.Appl.Pharmacol_219_226 |
| PubMedID: 17112559 |
| Title : Simulation of cholinesterase status at different scenarios of nerve agent exposure - Worek_2007_Toxicology_233_155 |
| Author(s) : Worek F , Eyer P , Szinicz L , Thiermann H |
| Ref : Toxicology , 233 :155 , 2007 |
| Abstract : |
| PubMedSearch : Worek_2007_Toxicology_233_155 |
| PubMedID: 16904807 |
| Title : Direct reaction of oximes with crotylsarin, cyclosarin, or VX in vitro - Becker_2007_Arch.Toxicol_81_415 |
| Author(s) : Becker G , Kawan A , Gutzeit D , Worek F , Szinicz L |
| Ref : Archives of Toxicology , 81 :415 , 2007 |
| Abstract : |
| PubMedSearch : Becker_2007_Arch.Toxicol_81_415 |
| PubMedID: 17151865 |
| Title : Apoptosis in sulfur mustard treated A549 cell cultures - Steinritz_2007_Life.Sci_80_2199 |
| Author(s) : Steinritz D , Emmler J , Hintz M , Worek F , Kreppel H , Szinicz L , Kehe K |
| Ref : Life Sciences , 80 :2199 , 2007 |
| Abstract : |
| PubMedSearch : Steinritz_2007_Life.Sci_80_2199 |
| PubMedID: 17229443 |
| Title : Testing of antidotes for organophosphorus compounds: experimental procedures and clinical reality - Eyer_2007_Toxicology_233_108 |
| Author(s) : Eyer P , Szinicz L , Thiermann H , Worek F , Zilker T |
| Ref : Toxicology , 233 :108 , 2007 |
| Abstract : |
| PubMedSearch : Eyer_2007_Toxicology_233_108 |
| PubMedID: 17010492 |
| Title : Application of kinetic-based computer modelling to evaluate the efficacy of HI 6 in percutaneous VX poisoning - Aurbek_2006_Toxicology_224_74 |
| Author(s) : Aurbek N , Thiermann H , Szinicz L , Eyer P , Worek F |
| Ref : Toxicology , 224 :74 , 2006 |
| Abstract : |
| PubMedSearch : Aurbek_2006_Toxicology_224_74 |
| PubMedID: 16740352 |
| Title : Analysis of inhibition, reactivation and aging kinetics of highly toxic organophosphorus compounds with human and pig acetylcholinesterase - Aurbek_2006_Toxicology_224_91 |
| Author(s) : Aurbek N , Thiermann H , Szinicz L , Eyer P , Worek F |
| Ref : Toxicology , 224 :91 , 2006 |
| Abstract : |
| PubMedSearch : Aurbek_2006_Toxicology_224_91 |
| PubMedID: 16720069 |
| Title : Effect of metoclopramide and ranitidine on the inhibition of human AChE by VX in vitro - Bartling_2005_J.Appl.Toxicol_25_568 |
| Author(s) : Bartling A , Thiermann H , Szinicz L , Worek F |
| Ref : J Appl Toxicol , 25 :568 , 2005 |
| Abstract : |
| PubMedSearch : Bartling_2005_J.Appl.Toxicol_25_568 |
| PubMedID: 16167316 |
| Title : Effects of oximes on muscle force and acetylcholinesterase activity in isolated mouse hemidiaphragms exposed to paraoxon - Thiermann_2005_Toxicology_214_190 |
| Author(s) : Thiermann H , Eyer P , Worek F , Szinicz L |
| Ref : Toxicology , 214 :190 , 2005 |
| Abstract : |
| PubMedSearch : Thiermann_2005_Toxicology_214_190 |
| PubMedID: 16040183 |
| Title : Estimation of oxime efficacy in nerve agent poisoning: a kinetic approach - Worek_2005_Chem.Biol.Interact_157-158_349 |
| Author(s) : Worek F , Szinicz L , Thiermann H |
| Ref : Chemico-Biological Interactions , 157-158 :349 , 2005 |
| Abstract : |
| PubMedSearch : Worek_2005_Chem.Biol.Interact_157-158_349 |
| PubMedID: 16266695 |
| Title : Correlation between red blood cell acetylcholinesterase activity and neuromuscular transmission in organophosphate poisoning - Thiermann_2005_Chem.Biol.Interact_157-158_345 |
| Author(s) : Thiermann H , Szinicz L , Eyer P , Zilker T , Worek F |
| Ref : Chemico-Biological Interactions , 157-158 :345 , 2005 |
| Abstract : |
| PubMedSearch : Thiermann_2005_Chem.Biol.Interact_157-158_345 |
| PubMedID: 16263103 |
| Title : Evaluation of oxime efficacy in nerve agent poisoning: development of a kinetic-based dynamic model - Worek_2005_Toxicol.Appl.Pharmacol_209_193 |
| Author(s) : Worek F , Szinicz L , Eyer P , Thiermann H |
| Ref : Toxicol Appl Pharmacol , 209 :193 , 2005 |
| Abstract : |
| PubMedSearch : Worek_2005_Toxicol.Appl.Pharmacol_209_193 |
| PubMedID: 15904945 |
| Title : Oximes for acute organophosphate pesticide poisoning - Buckley_2005_Cochrane.Database.Syst.Rev__CD005085 |
| Author(s) : Buckley NA , Eddleston M , Szinicz L |
| Ref : Cochrane Database Syst Rev , :CD005085 , 2005 |
| Abstract : |
| PubMedSearch : Buckley_2005_Cochrane.Database.Syst.Rev__CD005085 |
| PubMedID: 15654704 |
| Title : Diagnostic aspects of organophosphate poisoning - Worek_2005_Toxicology_214_182 |
| Author(s) : Worek F , Koller M , Thiermann H , Szinicz L |
| Ref : Toxicology , 214 :182 , 2005 |
| Abstract : |
| PubMedSearch : Worek_2005_Toxicology_214_182 |
| PubMedID: 16051411 |
| Title : Differences between organophosphorus insecticides in human self-poisoning: a prospective cohort study - Eddleston_2005_Lancet_366_1452 |
| Author(s) : Eddleston M , Eyer P , Worek F , Mohamed F , Senarathna L , von Meyer L , Juszczak E , Hittarage A , Azhar S , Dissanayake W , Sheriff MH , Szinicz L , Dawson AH , Buckley NA |
| Ref : Lancet , 366 :1452 , 2005 |
| Abstract : |
| PubMedSearch : Eddleston_2005_Lancet_366_1452 |
| PubMedID: 16243090 |
| Title : Kinetic analysis of interactions between human acetylcholinesterase, structurally different organophosphorus compounds and oximes - Worek_2004_Biochem.Pharmacol_68_2237 |
| Author(s) : Worek F , Thiermann H , Szinicz L , Eyer P |
| Ref : Biochemical Pharmacology , 68 :2237 , 2004 |
| Abstract : |
| PubMedSearch : Worek_2004_Biochem.Pharmacol_68_2237 |
| PubMedID: 15498514 |
| Title : Effect of organophosphorus hydrolysing enzymes on obidoxime-induced reactivation of organophosphate-inhibited human acetylcholinesterase - Herkenhoff_2004_Arch.Toxicol_78_338 |
| Author(s) : Herkenhoff S , Szinicz L , Rastogi VK , Cheng TC , DeFrank JJ , Worek F |
| Ref : Archives of Toxicology , 78 :338 , 2004 |
| Abstract : |
| PubMedSearch : Herkenhoff_2004_Arch.Toxicol_78_338 |
| PubMedID: 14985944 |
| Title : Reactivation and aging kinetics of human acetylcholinesterase inhibited by organophosphonylcholines - Worek_2004_Arch.Toxicol_78_212 |
| Author(s) : Worek F , Thiermann H , Szinicz L |
| Ref : Archives of Toxicology , 78 :212 , 2004 |
| Abstract : |
| PubMedSearch : Worek_2004_Arch.Toxicol_78_212 |
| PubMedID: 14647978 |
| Title : The effect of acetylcholinesterase-inhibition on depolarization-induced GABA release from rat striatal slices - Grasshoff_2003_Toxicology_184_149 |
| Author(s) : Grasshoff C , Gillessen T , Thiermann H , Wagner E , Szinicz L |
| Ref : Toxicology , 184 :149 , 2003 |
| Abstract : |
| PubMedSearch : Grasshoff_2003_Toxicology_184_149 |
| PubMedID: 12499118 |
| Title : Reactivation kinetics of acetylcholinesterase from different species inhibited by highly toxic organophosphates - Worek_2002_Arch.Toxicol_76_523 |
| Author(s) : Worek F , Reiter G , Eyer P , Szinicz L |
| Ref : Archives of Toxicology , 76 :523 , 2002 |
| Abstract : |
| PubMedSearch : Worek_2002_Arch.Toxicol_76_523 |
| PubMedID: 12242610 |
| Title : Oximes in acute organophosphorus pesticide poisoning: a systematic review of clinical trials - Eddleston_2002_QJM_95_275 |
| Author(s) : Eddleston M , Szinicz L , Eyer P , Buckley N |
| Ref : Qjm , 95 :275 , 2002 |
| Abstract : |
| PubMedSearch : Eddleston_2002_QJM_95_275 |
| PubMedID: 11978898 |
| Title : Internal standard high-performance liquid chromatography method for the determination of obidoxime in urine of organophosphate-poisoned patients - Grasshoff_2001_J.Chromatogr.B.Biomed.Sci.Appl_753_203 |
| Author(s) : Grasshoff C , Thiermann H , Gillessen T , Zilker T , Szinicz L |
| Ref : Journal of Chromatography B Biomed Sci Appl , 753 :203 , 2001 |
| Abstract : |
| PubMedSearch : Grasshoff_2001_J.Chromatogr.B.Biomed.Sci.Appl_753_203 |
| PubMedID: 11334332 |
| Title : Effect of human plasma on the reactivation of sarin-inhibited human erythrocyte acetylcholinesterase - Worek_2000_Arch.Toxicol_74_21 |
| Author(s) : Worek F , Eyer P , Kiderlen D , Thiermann H , Szinicz L |
| Ref : Archives of Toxicology , 74 :21 , 2000 |
| Abstract : |
| PubMedSearch : Worek_2000_Arch.Toxicol_74_21 |
| PubMedID: 10817663 |
| Title : Modern strategies in therapy of organophosphate poisoning - Thiermann_1999_Toxicol.Lett_107_233 |
| Author(s) : Thiermann H , Szinicz L , Eyer F , Worek F , Eyer P , Felgenhauer N , Zilker T |
| Ref : Toxicol Lett , 107 :233 , 1999 |
| Abstract : |
| PubMedSearch : Thiermann_1999_Toxicol.Lett_107_233 |
| PubMedID: 10414801 |
| Title : Acetylcholinesterase, a Versatile Protein - |
| Author(s) : Szinicz L , Thiermann H , Worek F , Eyer P |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :269 , 1998 |
| PubMedID: |
| Title : Reactivating potency of obidoxime, pralidoxime, HI 6 and HLo 7 in human erythrocyte acetylcholinesterase inhibited by highly toxic organophosphorus compounds - Worek_1998_Arch.Toxicol_72_237 |
| Author(s) : Worek F , Widmann R , Knopff O , Szinicz L |
| Ref : Archives of Toxicology , 72 :237 , 1998 |
| Abstract : |
| PubMedSearch : Worek_1998_Arch.Toxicol_72_237 |
| PubMedID: 9587020 |
| Title : Inhibition, reactivation and aging kinetics of cyclohexylmethylphosphonofluoridate-inhibited human cholinesterases - Worek_1998_Arch.Toxicol_72_580 |
| Author(s) : Worek F , Eyer P , Szinicz L |
| Ref : Archives of Toxicology , 72 :580 , 1998 |
| Abstract : |
| PubMedSearch : Worek_1998_Arch.Toxicol_72_580 |
| PubMedID: 9806430 |
| Title : Reappraisal of indications and limitations of oxime therapy in organophosphate poisoning - Worek_1997_Hum.Exp.Toxicol_16_466 |
| Author(s) : Worek F , Backer M , Thiermann H , Szinicz L , Mast U , Klimmek R , Eyer P |
| Ref : Hum Exp Toxicol , 16 :466 , 1997 |
| Abstract : |
| PubMedSearch : Worek_1997_Hum.Exp.Toxicol_16_466 |
| PubMedID: 9292287 |
| Title : Direct reaction of oximes with sarin, soman, or tabun in vitro - Becker_1997_Arch.Toxicol_71_714 |
| Author(s) : Becker G , Kawan A , Szinicz L |
| Ref : Archives of Toxicology , 71 :714 , 1997 |
| Abstract : |
| PubMedSearch : Becker_1997_Arch.Toxicol_71_714 |
| PubMedID: 9363846 |
| Title : Reactivation by various oximes of human erythrocyte acetylcholinesterase inhibited by different organophosphorus compounds - Worek_1996_Arch.Toxicol_70_497 |
| Author(s) : Worek F , Kirchner T , Backer M , Szinicz L |
| Ref : Archives of Toxicology , 70 :497 , 1996 |
| Abstract : |
| PubMedSearch : Worek_1996_Arch.Toxicol_70_497 |
| PubMedID: 8783813 |
| Title : Methantheline improves the reactivation by HI 6 of human erythrocyte acetylcholinesterase inhibited by soman in vitro - Hallek_1995_Arch.Toxicol_70_16 |
| Author(s) : Hallek M , Szinicz L |
| Ref : Archives of Toxicology , 70 :16 , 1995 |
| Abstract : |
| PubMedSearch : Hallek_1995_Arch.Toxicol_70_16 |
| PubMedID: 8750900 |
| Title : Effects of atropine and soman on the pharmacokinetics of the oxime HLo 7 dimethanesulfonate in anesthetized guinea-pigs - Worek_1995_Drug.Chem.Toxicol_18_137 |
| Author(s) : Worek F , Klimmek R , Szinicz L |
| Ref : Drug & Chemical Toxicology , 18 :137 , 1995 |
| Abstract : |
| PubMedSearch : Worek_1995_Drug.Chem.Toxicol_18_137 |
| PubMedID: 7497908 |
| Title : Arrhythmias in organophosphate poisoning: effect of atropine and bispyridinium oximes - Worek_1995_Arch.Int.Pharmacodyn.Ther_329_418 |
| Author(s) : Worek F , Kleine A , Falke K , Szinicz L |
| Ref : Archives Internationales de Pharmacodynamie et de Therapie , 329 :418 , 1995 |
| Abstract : |
| PubMedSearch : Worek_1995_Arch.Int.Pharmacodyn.Ther_329_418 |
| PubMedID: 8546540 |
| Title : Cardiorespiratory function in nerve agent poisoned and oxime + atropine treated guinea-pigs: effect of pyridostigmine pretreatment - Worek_1995_Arch.Toxicol_69_322 |
| Author(s) : Worek F , Szinicz L |
| Ref : Archives of Toxicology , 69 :322 , 1995 |
| Abstract : |
| PubMedSearch : Worek_1995_Arch.Toxicol_69_322 |
| PubMedID: 7654137 |
| Title : Effect of pyridostigmine pretreatment on cardiorespiratory function in tabun poisoning - Worek_1995_Human.Exp.Toxicol_14_634 |
| Author(s) : Worek F , Kleine A , Szinicz L |
| Ref : Hum Exp Toxicol , 14 :634 , 1995 |
| Abstract : |
| PubMedSearch : Worek_1995_Human.Exp.Toxicol_14_634 |
| PubMedID: 7576830 |
| Title : Effect of atropine and bispyridinium oximes on respiratory and circulatory function in guinea-pigs poisoned by sarin - Worek_1995_Toxicology_95_123 |
| Author(s) : Worek F , Kirchner T , Szinicz L |
| Ref : Toxicology , 95 :123 , 1995 |
| Abstract : |
| PubMedSearch : Worek_1995_Toxicology_95_123 |
| PubMedID: 7825179 |
| Title : Treatment of tabun poisoned guinea-pigs with atropine, HLo 7 or HI 6: effect on respiratory and circulatory function - Worek_1994_Arch.Toxicol_68_231 |
| Author(s) : Worek F , Kirchner T , Szinicz L |
| Ref : Archives of Toxicology , 68 :231 , 1994 |
| Abstract : |
| PubMedSearch : Worek_1994_Arch.Toxicol_68_231 |
| PubMedID: 8067895 |
| Title : Effect of atropine, HLo 7 and HI 6 on respiratory and circulatory function in guinea-pigs poisoned by O-ethyl S-[2-(diisopropylamino) ethyl] methylphosponothioate (VX) - Worek_1994_Pharmacol.Toxicol_75_302 |
| Author(s) : Worek F , Kirchner T , Szinicz L |
| Ref : Pharmacol Toxicol , 75 :302 , 1994 |
| Abstract : |
| PubMedSearch : Worek_1994_Pharmacol.Toxicol_75_302 |
| PubMedID: 7870702 |
| Title : A homogeneous immunological detection system for soman using the in vitro protection of acetylcholinesterase by a monoclonal antibody - Erhard_1993_Arch.Toxicol_67_220 |
| Author(s) : Erhard MH , Jungling A , Schoneberg T , Szinicz L , Losch U |
| Ref : Archives of Toxicology , 67 :220 , 1993 |
| Abstract : |
| PubMedSearch : Erhard_1993_Arch.Toxicol_67_220 |
| PubMedID: 8494502 |
| Title : Analysis of cardiovascular and respiratory effects of various doses of soman in guinea-pigs: efficacy of atropine treatment - Worek_1993_Arch.Int.Pharmacodyn.Ther_325_96 |
| Author(s) : Worek F , Szinicz L |
| Ref : Archives Internationales de Pharmacodynamie et de Therapie , 325 :96 , 1993 |
| Abstract : |
| PubMedSearch : Worek_1993_Arch.Int.Pharmacodyn.Ther_325_96 |
| PubMedID: 8110034 |
| Title : Atropine and oxime treatment in lethal soman poisoning of anaesthetized guinea-pigs: HLo 7 dimethanesulfonate versus HI 6 dichloride - Worek_1993_Pharmacol.Toxicol_72_13 |
| Author(s) : Worek F , Szinicz L |
| Ref : Pharmacol Toxicol , 72 :13 , 1993 |
| Abstract : |
| PubMedSearch : Worek_1993_Pharmacol.Toxicol_72_13 |
| PubMedID: 8441735 |
| Title : Investigation of acute cardiovascular and respiratory toxicity of HLo 7 dimethanesulfonate and HI 6 dichloride in anaesthetized guinea-pigs - Worek_1993_Pharmacol.Toxicol_73_91 |
| Author(s) : Worek F , Szinicz L |
| Ref : Pharmacol Toxicol , 73 :91 , 1993 |
| Abstract : |
| PubMedSearch : Worek_1993_Pharmacol.Toxicol_73_91 |
| PubMedID: 8248012 |
| Title : HLo 7 dimethanesulfonate, a potent bispyridinium-dioxime against anticholinesterases - Eyer_1992_Arch.Toxicol_66_603 |
| Author(s) : Eyer P , Hagedorn I , Klimmek R , Lippstreu P , Loffler M , Oldiges H , Spohrer U , Steidl I , Szinicz L , Worek F |
| Ref : Archives of Toxicology , 66 :603 , 1992 |
| Abstract : |
| PubMedSearch : Eyer_1992_Arch.Toxicol_66_603 |
| PubMedID: 1482283 |
| Title : Detection of the organophosphorus nerve agent soman by an ELISA using monoclonal antibodies - Erhard_1990_Arch.Toxicol_64_580 |
| Author(s) : Erhard MH , Kuhlmann R , Szinicz L , Losch U |
| Ref : Archives of Toxicology , 64 :580 , 1990 |
| Abstract : |
| PubMedSearch : Erhard_1990_Arch.Toxicol_64_580 |
| PubMedID: 2073131 |
| Title : Studies on the role of central catecholaminergic mechanisms in the antidotal effect of the oxime HI 6 in soman poisoned mice - Reithmann_1988_Arch.Toxicol_62_41 |
| Author(s) : Reithmann C , Arbogast H , Hallek M , Auburger G , Szinicz L |
| Ref : Archives of Toxicology , 62 :41 , 1988 |
| Abstract : |
| PubMedSearch : Reithmann_1988_Arch.Toxicol_62_41 |
| PubMedID: 3190454 |
| Title : Effects of some mono- and bisquaternary ammonium compounds on the reactivatability of soman-inhibited human acetylcholinesterase in vitro - Hallek_1988_Biochem.Pharmacol_37_819 |
| Author(s) : Hallek M , Szinicz L |
| Ref : Biochemical Pharmacology , 37 :819 , 1988 |
| Abstract : |
| PubMedSearch : Hallek_1988_Biochem.Pharmacol_37_819 |
| PubMedID: 3345199 |