MTR-1
elAChE IC50 >100 microM ; eqBChE IC50 0.37 +/- 0.02 microM
General
Type : Derivative of Bambuterol, Derivative of Rivastigmine, Carbamate, tert-Butyl
Chemical_Nomenclature :
Canonical SMILES : C1=C(C=CC=C1C(CNC(C)(C)C)O)OC(=O)N(CC)C
InChI : InChI=1S\/C16H26N2O3\/c1-6-18(5)15(20)21-13-9-7-8-12(10-13)14(19)11-17-16(2,3)4\/h7-10,14,17,19H,6,11H2,1-5H3
InChIKey : DULYNLIGBAIBCW-UHFFFAOYSA-N
Other name(s) :
Target
Families : MTR-1 ligand of proteins in family
BCHE
Protein :
human-BCHE
References (1)
| Title : Rivastigmine-Bambuterol Hybrids as Selective Butyrylcholinesterase Inhibitors - Wu_2023_Molecules_29_ |
| Author(s) : Wu J , Tan Z , Pistolozzi M , Tan W |
| Ref : Molecules , 29 : , 2023 |
| Abstract : |
| PubMedSearch : Wu_2023_Molecules_29_ |
| PubMedID: 38202655 |