Derivative of Rivastigmine

General

Rivastigmine (Exelon) is a cholinesterase inhibitor used for the treatment of mild to moderate Alzheimer's disease. Used also as building block for multitarget compounds

Inhibitor	Main targeted enzyme families	Type
Fluoxetine-rivastigmine-Cpd8	ACHE	Drug Pro-Drug Carbamate Derivative of Rivastigmine Stigmine Multitarget Sodium:neurotransmitter symporter
CHEMBL190322	ACHE BCHE	Carbamate Derivative of Rivastigmine Stigmine Chromen Sulfur Compound
CHEMBL189907	ACHE BCHE	Carbamate Derivative of Rivastigmine Stigmine Indole
CHEMBL274107	ACHE BCHE	Carbamate Derivative of Rivastigmine Stigmine Chromen
HY-157437	ACHE BCHE	Carbamate Derivative of Tacrine Acridine Alkyl linked bis-ligand Derivative of Rivastigmine Stigmine
RIV-Piperidine-Cpd6a	BCHE	Piperidine Derivative of Rivastigmine Stigmine Carbamate
MP30	BCHE	Multitarget Derivative of Rivastigmine Stigmine Carbamate Antioxidant Sulfur Compound
RIV-IND-5b2	ACHE	Monoamine-oxidase-inhibitor Multitarget Derivative of Rivastigmine Stigmine Indole anti-Abeta-aggregation Antioxidant
RIV-BIM-4d	ACHE	Monoamine-oxidase-inhibitor Multitarget Derivative of Rivastigmine Stigmine Benzimidazole
Rivastigmine-Donepezil-COR783	ACHE BCHE	Cannabinoid-Receptor-ligand Derivative of Rivastigmine Stigmine Multitarget Sulfur Compound Derivative of Donepezil Carbamate Adamantyl
Cpd35-Rivastigmine-5-HT6	BCHE	Derivative of Rivastigmine Stigmine Multitarget 5-HT-receptor-ligand Sulfur Compound Sulfonamide Indole Carbamate Alkyl linked bis-ligand anti-Abeta-aggregation
Idalopirdine-rivastigmine	BCHE	Drug Pro-Drug Carbamate Derivative of Rivastigmine Stigmine Multitarget 5-HT-receptor-ligand
CHEMBL1784957	ACHE	Drug Pro-Drug Carbamate Derivative of Rivastigmine Stigmine
6EUL-BY2	BCHE	Carbamate Derivative of Rivastigmine Stigmine
RIV-BIMb-5d	BCHE	Derivative of Rivastigmine Stigmine Carbamate Carboxamide Benzimidazole
Salicylic-donepezil-rivastigmine-5a	BCHE	Carbamate Derivative of Donepezil Salicylic Derivative of Rivastigmine Stigmine Benzylpiperidine
NAP	ACHE	Derivative of Rivastigmine Stigmine
MTR-3	BCHE	Derivative of Bambuterol Derivative of Rivastigmine Stigmine Carbamate tert-Butyl
MTR-1	BCHE	Derivative of Bambuterol Derivative of Rivastigmine Stigmine Carbamate tert-Butyl
Miotine	ACHE	Carbamate Derivative of Rivastigmine Stigmine
Rivastigmine	ACHE	Derivative of Rivastigmine Stigmine Carbamate Drug
Fluoxetine-rivastigmine-Cpd8	ACHE	Drug Pro-Drug Carbamate Derivative of Rivastigmine Stigmine Multitarget Sodium:neurotransmitter symporter
CHEMBL190322	ACHE BCHE	Carbamate Derivative of Rivastigmine Stigmine Chromen Sulfur Compound
CHEMBL189907	ACHE BCHE	Carbamate Derivative of Rivastigmine Stigmine Indole
CHEMBL274107	ACHE BCHE	Carbamate Derivative of Rivastigmine Stigmine Chromen
HY-157437	ACHE BCHE	Carbamate Derivative of Tacrine Acridine Alkyl linked bis-ligand Derivative of Rivastigmine Stigmine
RIV-Piperidine-Cpd6a	BCHE	Piperidine Derivative of Rivastigmine Stigmine Carbamate
MP30	BCHE	Multitarget Derivative of Rivastigmine Stigmine Carbamate Antioxidant Sulfur Compound
RIV-IND-5b2	ACHE	Monoamine-oxidase-inhibitor Multitarget Derivative of Rivastigmine Stigmine Indole anti-Abeta-aggregation Antioxidant
RIV-BIM-4d	ACHE	Monoamine-oxidase-inhibitor Multitarget Derivative of Rivastigmine Stigmine Benzimidazole
Rivastigmine-Donepezil-COR783	ACHE BCHE	Cannabinoid-Receptor-ligand Derivative of Rivastigmine Stigmine Multitarget Sulfur Compound Derivative of Donepezil Carbamate Adamantyl
Cpd35-Rivastigmine-5-HT6	BCHE	Derivative of Rivastigmine Stigmine Multitarget 5-HT-receptor-ligand Sulfur Compound Sulfonamide Indole Carbamate Alkyl linked bis-ligand anti-Abeta-aggregation
Idalopirdine-rivastigmine	BCHE	Drug Pro-Drug Carbamate Derivative of Rivastigmine Stigmine Multitarget 5-HT-receptor-ligand
CHEMBL1784957	ACHE	Drug Pro-Drug Carbamate Derivative of Rivastigmine Stigmine
6EUL-BY2	BCHE	Carbamate Derivative of Rivastigmine Stigmine
RIV-BIMb-5d	BCHE	Derivative of Rivastigmine Stigmine Carbamate Carboxamide Benzimidazole
Salicylic-donepezil-rivastigmine-5a	BCHE	Carbamate Derivative of Donepezil Salicylic Derivative of Rivastigmine Stigmine Benzylpiperidine
NAP	ACHE	Derivative of Rivastigmine Stigmine
MTR-3	BCHE	Derivative of Bambuterol Derivative of Rivastigmine Stigmine Carbamate tert-Butyl
MTR-1	BCHE	Derivative of Bambuterol Derivative of Rivastigmine Stigmine Carbamate tert-Butyl
Miotine	ACHE	Carbamate Derivative of Rivastigmine Stigmine
Rivastigmine	ACHE	Derivative of Rivastigmine Stigmine Carbamate Drug
Fluoxetine-rivastigmine-Cpd8	ACHE	Drug Pro-Drug Carbamate Derivative of Rivastigmine Stigmine Multitarget Sodium:neurotransmitter symporter
CHEMBL190322	ACHE BCHE	Carbamate Derivative of Rivastigmine Stigmine Chromen Sulfur Compound
CHEMBL189907	ACHE BCHE	Carbamate Derivative of Rivastigmine Stigmine Indole
CHEMBL274107	ACHE BCHE	Carbamate Derivative of Rivastigmine Stigmine Chromen
HY-157437	ACHE BCHE	Carbamate Derivative of Tacrine Acridine Alkyl linked bis-ligand Derivative of Rivastigmine Stigmine
RIV-Piperidine-Cpd6a	BCHE	Piperidine Derivative of Rivastigmine Stigmine Carbamate
MP30	BCHE	Multitarget Derivative of Rivastigmine Stigmine Carbamate Antioxidant Sulfur Compound
RIV-IND-5b2	ACHE	Monoamine-oxidase-inhibitor Multitarget Derivative of Rivastigmine Stigmine Indole anti-Abeta-aggregation Antioxidant
RIV-BIM-4d	ACHE	Monoamine-oxidase-inhibitor Multitarget Derivative of Rivastigmine Stigmine Benzimidazole
Rivastigmine-Donepezil-COR783	ACHE BCHE	Cannabinoid-Receptor-ligand Derivative of Rivastigmine Stigmine Multitarget Sulfur Compound Derivative of Donepezil Carbamate Adamantyl
Cpd35-Rivastigmine-5-HT6	BCHE	Derivative of Rivastigmine Stigmine Multitarget 5-HT-receptor-ligand Sulfur Compound Sulfonamide Indole Carbamate Alkyl linked bis-ligand anti-Abeta-aggregation
Idalopirdine-rivastigmine	BCHE	Drug Pro-Drug Carbamate Derivative of Rivastigmine Stigmine Multitarget 5-HT-receptor-ligand
CHEMBL1784957	ACHE	Drug Pro-Drug Carbamate Derivative of Rivastigmine Stigmine
6EUL-BY2	BCHE	Carbamate Derivative of Rivastigmine Stigmine
RIV-BIMb-5d	BCHE	Derivative of Rivastigmine Stigmine Carbamate Carboxamide Benzimidazole
Salicylic-donepezil-rivastigmine-5a	BCHE	Carbamate Derivative of Donepezil Salicylic Derivative of Rivastigmine Stigmine Benzylpiperidine
NAP	ACHE	Derivative of Rivastigmine Stigmine
MTR-3	BCHE	Derivative of Bambuterol Derivative of Rivastigmine Stigmine Carbamate tert-Butyl
MTR-1	BCHE	Derivative of Bambuterol Derivative of Rivastigmine Stigmine Carbamate tert-Butyl
Miotine	ACHE	Carbamate Derivative of Rivastigmine Stigmine
Rivastigmine	ACHE	Derivative of Rivastigmine Stigmine Carbamate Drug