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Type Inhibitor
Stigmine
Stigmine
General
A class of acetylcholinesterase inhibitors. Indirect parasympathomimetic drug, sometimes called a cholinomimetic drug also called cholinergic drugs because acetylcholine (ACh) is the neurotransmitter used by the PSNS. Carbamate linked to a C6 ring
Inhibitor
Main targeted enzyme families
Type
Structure
CHEMBL190322
ACHE
BCHE
Carbamate
Derivative of Rivastigmine
Stigmine
Chromen
Sulfur Compound
CHEMBL189907
ACHE
BCHE
Carbamate
Derivative of Rivastigmine
Stigmine
Indole
CHEMBL274107
ACHE
BCHE
Carbamate
Derivative of Rivastigmine
Stigmine
Chromen
HY-157437
ACHE
BCHE
Carbamate
Derivative of Tacrine
Acridine
Alkyl linked bis-ligand
Derivative of Rivastigmine
Stigmine
RIV-Piperidine-Cpd6a
BCHE
Piperidine
Derivative of Rivastigmine
Stigmine
Carbamate
MP30
BCHE
Multitarget
Derivative of Rivastigmine
Stigmine
Carbamate
Antioxidant
Sulfur Compound
RIV-IND-5b2
ACHE
Monoamine-oxidase-inhibitor
Multitarget
Derivative of Rivastigmine
Stigmine
Indole
anti-Abeta-aggregation
Antioxidant
RIV-BIM-4d
ACHE
Monoamine-oxidase-inhibitor
Multitarget
Derivative of Rivastigmine
Stigmine
Benzimidazole
Rivastigmine-Donepezil-COR783
ACHE
BCHE
Cannabinoid-Receptor-ligand
Derivative of Rivastigmine
Stigmine
Multitarget
Sulfur Compound
Derivative of Donepezil
Carbamate
Adamantyl
Xanthostigmine
ACHE
BCHE
Stigmine
Carbamate
Xanthene
Cyclohexylmethylcarbamate-phenethylnorphysostigmine-3u
BCHE
Derivative of physostigmine-eserine
Stigmine
Carbamate
TL-1238
BCHE
ACHE
Derivative of Neostigmine~Prostigmine
Stigmine
Carbamate
Ammonium
S208
BCHE
ACHE
Derivative of Neostigmine~Prostigmine
Stigmine
Carbamate
Ammonium
Cpd35-Rivastigmine-5-HT6
BCHE
Derivative of Rivastigmine
Stigmine
Multitarget
5-HT-receptor-ligand
Sulfur Compound
Sulfonamide
Indole
Carbamate
Alkyl linked bis-ligand
anti-Abeta-aggregation
Idalopirdine-rivastigmine
BCHE
Drug
Pro-Drug
Carbamate
Derivative of Rivastigmine
Stigmine
Multitarget
5-HT-receptor-ligand
CHEMBL1784957
ACHE
Drug
Pro-Drug
Carbamate
Derivative of Rivastigmine
Stigmine
6EUL-BY2
BCHE
Carbamate
Derivative of Rivastigmine
Stigmine
RIV-BIMb-5d
BCHE
Derivative of Rivastigmine
Stigmine
Carbamate
Benzimidazole
Debromoflustramine-B
BCHE
Natural
Pyrrolidine
Indole
Derivative of physostigmine-eserine
Stigmine
Salicylic-donepezil-rivastigmine-5a
BCHE
Carbamate
Derivative of Donepezil
Salicylic
Derivative of Rivastigmine
Stigmine
Benzylpiperidine
Bis-Noreseroline
ACHE
Leaving group
Indole
Derivative of physostigmine-eserine
Stigmine
Cymserine
BCHE
Derivative of physostigmine-eserine
Stigmine
Carbamate
Indole
Dihydrobenzodioxepine-cymeserine
BCHE
Derivative of physostigmine-eserine
Stigmine
Carbamate
Tetrahydrofurobenzofuran-cymserine
ACHE
Derivative of physostigmine-eserine
Stigmine
Carbamate
Benzofuran
(-)-phenethylcymserine
Carb_B_Chordata
BCHE
ACHE
Derivative of physostigmine-eserine
Stigmine
Carbamate
Cymyl-carbamate-physovenol
ACHE
Derivative of physostigmine-eserine
Stigmine
Carbamate
N1-Phenethylnorcymserine
BCHE
Derivative of physostigmine-eserine
Stigmine
Carbamate
Indole
Bisnorcymserine
BCHE
ACHE
Carbamate
Indole
Derivative of physostigmine-eserine
Stigmine
NAP
ACHE
Derivative of Rivastigmine
Stigmine
Physovenine
ACHE
Carbamate
Natural
Indole
Derivative of physostigmine-eserine
Stigmine
Ganstigmine
ACHE
Derivative of physostigmine-eserine
Stigmine
Carbamate
Indole
Organochlorine
MTR-3
BCHE
Derivative of Bambuterol
Derivative of Rivastigmine
Stigmine
Carbamate
tert-Butyl
MTR-1
BCHE
Derivative of Bambuterol
Derivative of Rivastigmine
Stigmine
Carbamate
tert-Butyl
Miotine
ACHE
Carbamate
Derivative of Rivastigmine
Stigmine
Rivastigmine
ACHE
Derivative of Rivastigmine
Stigmine
Carbamate
Drug
Eseroline
ACHE
Derivative of physostigmine-eserine
Stigmine
Indole
Geneserine
ACHE
BCHE
Natural
Indole
Carbamate
Derivative of physostigmine-eserine
Stigmine
Oxazine
Geneseroline
Natural
Indole
Derivative of physostigmine-eserine
Stigmine
Leaving group
Oxazine
Heptylphysostigmine
ACHE
Derivative of physostigmine-eserine
Stigmine
Carbamate
Indole
MF231
ACHE
Derivative of physostigmine-eserine
Stigmine
Carbamate
Morpholine
Indole
MF217
ACHE
Derivative of physostigmine-eserine
Stigmine
Carbamate
Morpholine
Indole
MF268
ACHE
Derivative of physostigmine-eserine
Stigmine
Carbamate
Morpholine
Indole
Neostigmine~Prostigmine
ACHE
BCHE
Stigmine
Derivative of Neostigmine~Prostigmine
Carbamate
Trimethylammonium
Ammonium
Posiphen
ACHE
Derivative of physostigmine-eserine
Stigmine
Carbamate
Drug
Indole
Phenserine
ACHE
Derivative of physostigmine-eserine
Stigmine
Carbamate
Drug
Indole
Physostigmine-methiodide
ACHE
Derivative of physostigmine-eserine
Stigmine
Natural_modified
Carbamate
Indole
Physostigmine~Eserine
ACHE
BCHE
Arylacetamide_deacetylase
Derivative of physostigmine-eserine
Stigmine
Natural
Carbamate
Drug
Indole
Distigmine
BCHE
Carbamate
Stigmine
Drug
Pyridine
Pyridostigmine
BCHE
ACHE
Carbamate
Stigmine
Drug
Pyridine
Quilostigmine
ACHE
Derivative of physostigmine-eserine
Stigmine
Carbamate
Isoquinoline
Indole
Tolserine
ACHE
BCHE
Derivative of physostigmine-eserine
Stigmine
Carbamate
Indole
NTE inhibitor
Not AlphaBeta Hydrolase target
OPIDN-OP