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Stigmine

General

A class of acetylcholinesterase inhibitors. Indirect parasympathomimetic drug, sometimes called a cholinomimetic drug also called cholinergic drugs because acetylcholine (ACh) is the neurotransmitter used by the PSNS. Carbamate linked to a C6 ring
Inhibitor Main targeted enzyme families Type Structure
CHEMBL190322 ACHE BCHE Carbamate Derivative of Rivastigmine Stigmine Chromen Sulfur Compound
CHEMBL189907 ACHE BCHE Carbamate Derivative of Rivastigmine Stigmine Indole
CHEMBL274107 ACHE BCHE Carbamate Derivative of Rivastigmine Stigmine Chromen
HY-157437 ACHE BCHE Carbamate Derivative of Tacrine Acridine Alkyl linked bis-ligand Derivative of Rivastigmine Stigmine
RIV-Piperidine-Cpd6a BCHE Piperidine Derivative of Rivastigmine Stigmine Carbamate
MP30 BCHE Multitarget Derivative of Rivastigmine Stigmine Carbamate Antioxidant Sulfur Compound
RIV-IND-5b2 ACHE Monoamine-oxidase-inhibitor Multitarget Derivative of Rivastigmine Stigmine Indole anti-Abeta-aggregation Antioxidant
RIV-BIM-4d ACHE Monoamine-oxidase-inhibitor Multitarget Derivative of Rivastigmine Stigmine Benzimidazole
Rivastigmine-Donepezil-COR783 ACHE BCHE Cannabinoid-Receptor-ligand Derivative of Rivastigmine Stigmine Multitarget Sulfur Compound Derivative of Donepezil Carbamate Adamantyl
Xanthostigmine ACHE BCHE Stigmine Carbamate Xanthene
Cyclohexylmethylcarbamate-phenethylnorphysostigmine-3u BCHE Derivative of physostigmine-eserine Stigmine Carbamate
TL-1238 BCHE ACHE Derivative of Neostigmine~Prostigmine Stigmine Carbamate Ammonium
S208 BCHE ACHE Derivative of Neostigmine~Prostigmine Stigmine Carbamate Ammonium
Cpd35-Rivastigmine-5-HT6 BCHE Derivative of Rivastigmine Stigmine Multitarget 5-HT-receptor-ligand Sulfur Compound Sulfonamide Indole Carbamate Alkyl linked bis-ligand anti-Abeta-aggregation
Idalopirdine-rivastigmine BCHE Drug Pro-Drug Carbamate Derivative of Rivastigmine Stigmine Multitarget 5-HT-receptor-ligand
CHEMBL1784957 ACHE Drug Pro-Drug Carbamate Derivative of Rivastigmine Stigmine
6EUL-BY2 BCHE Carbamate Derivative of Rivastigmine Stigmine
RIV-BIMb-5d BCHE Derivative of Rivastigmine Stigmine Carbamate Benzimidazole
Debromoflustramine-B BCHE Natural Pyrrolidine Indole Derivative of physostigmine-eserine Stigmine
Salicylic-donepezil-rivastigmine-5a BCHE Carbamate Derivative of Donepezil Salicylic Derivative of Rivastigmine Stigmine Benzylpiperidine
Bis-Noreseroline ACHE Leaving group Indole Derivative of physostigmine-eserine Stigmine
Cymserine BCHE Derivative of physostigmine-eserine Stigmine Carbamate Indole
Dihydrobenzodioxepine-cymeserine BCHE Derivative of physostigmine-eserine Stigmine Carbamate
Tetrahydrofurobenzofuran-cymserine ACHE Derivative of physostigmine-eserine Stigmine Carbamate Benzofuran
(-)-phenethylcymserine Carb_B_Chordata BCHE ACHE Derivative of physostigmine-eserine Stigmine Carbamate
Cymyl-carbamate-physovenol ACHE Derivative of physostigmine-eserine Stigmine Carbamate
N1-Phenethylnorcymserine BCHE Derivative of physostigmine-eserine Stigmine Carbamate Indole
Bisnorcymserine BCHE ACHE Carbamate Indole Derivative of physostigmine-eserine Stigmine
NAP ACHE Derivative of Rivastigmine Stigmine
Physovenine ACHE Carbamate Natural Indole Derivative of physostigmine-eserine Stigmine
Ganstigmine ACHE Derivative of physostigmine-eserine Stigmine Carbamate Indole Organochlorine
MTR-3 BCHE Derivative of Bambuterol Derivative of Rivastigmine Stigmine Carbamate tert-Butyl
MTR-1 BCHE Derivative of Bambuterol Derivative of Rivastigmine Stigmine Carbamate tert-Butyl
Miotine ACHE Carbamate Derivative of Rivastigmine Stigmine
Rivastigmine ACHE Derivative of Rivastigmine Stigmine Carbamate Drug
Eseroline ACHE Derivative of physostigmine-eserine Stigmine Indole
Geneserine ACHE BCHE Natural Indole Carbamate Derivative of physostigmine-eserine Stigmine Oxazine
Geneseroline Natural Indole Derivative of physostigmine-eserine Stigmine Leaving group Oxazine
Heptylphysostigmine ACHE Derivative of physostigmine-eserine Stigmine Carbamate Indole
MF231 ACHE Derivative of physostigmine-eserine Stigmine Carbamate Morpholine Indole
MF217 ACHE Derivative of physostigmine-eserine Stigmine Carbamate Morpholine Indole
MF268 ACHE Derivative of physostigmine-eserine Stigmine Carbamate Morpholine Indole
Neostigmine~Prostigmine ACHE BCHE Stigmine Derivative of Neostigmine~Prostigmine Carbamate Trimethylammonium Ammonium
Posiphen ACHE Derivative of physostigmine-eserine Stigmine Carbamate Drug Indole
Phenserine ACHE Derivative of physostigmine-eserine Stigmine Carbamate Drug Indole
Physostigmine-methiodide ACHE Derivative of physostigmine-eserine Stigmine Natural_modified Carbamate Indole
Physostigmine~Eserine ACHE BCHE Arylacetamide_deacetylase Derivative of physostigmine-eserine Stigmine Natural Carbamate Drug Indole
Distigmine BCHE Carbamate Stigmine Drug Pyridine
Pyridostigmine BCHE ACHE Carbamate Stigmine Drug Pyridine
Quilostigmine ACHE Derivative of physostigmine-eserine Stigmine Carbamate Isoquinoline Indole
Tolserine ACHE BCHE Derivative of physostigmine-eserine Stigmine Carbamate Indole NTE inhibitor Not AlphaBeta Hydrolase target OPIDN-OP
CHEMBL190322 ACHE BCHE Carbamate Derivative of Rivastigmine Stigmine Chromen Sulfur compound
CHEMBL189907 ACHE BCHE Carbamate Derivative of Rivastigmine Stigmine Indole
CHEMBL274107 ACHE BCHE Carbamate Derivative of Rivastigmine Stigmine Chromen
HY-157437 ACHE BCHE Carbamate Derivative of Tacrine Acridine Alkyl linked bis-ligand Derivative of Rivastigmine Stigmine
RIV-Piperidine-Cpd6a BCHE Piperidine Derivative of Rivastigmine Stigmine Carbamate
MP30 BCHE Multitarget Derivative of Rivastigmine Stigmine Carbamate Antioxidant Sulfur compound
RIV-IND-5b2 ACHE Monoamine-oxidase-inhibitor Multitarget Derivative of Rivastigmine Stigmine Indole anti-Abeta-aggregation Antioxidant
RIV-BIM-4d ACHE Monoamine-oxidase-inhibitor Multitarget Derivative of Rivastigmine Stigmine Benzimidazole
Rivastigmine-Donepezil-COR783 ACHE BCHE Cannabinoid-Receptor-ligand Derivative of Rivastigmine Stigmine Multitarget Sulfur compound Derivative of Donepezil Carbamate Adamantyl
Xanthostigmine ACHE BCHE Stigmine Carbamate Xanthene
Cyclohexylmethylcarbamate-phenethylnorphysostigmine-3u BCHE Derivative of physostigmine-eserine Stigmine Carbamate
TL-1238 BCHE ACHE Derivative of Neostigmine~Prostigmine Stigmine Carbamate Ammonium
S208 BCHE ACHE Derivative of Neostigmine~Prostigmine Stigmine Carbamate Ammonium
Cpd35-Rivastigmine-5-HT6 BCHE Derivative of Rivastigmine Stigmine Multitarget 5-HT-receptor-ligand Sulfur compound Sulfonamide Indole Carbamate Alkyl linked bis-ligand anti-Abeta-aggregation
Idalopirdine-rivastigmine BCHE Drug Pro-Drug Carbamate Derivative of Rivastigmine Stigmine Multitarget 5-HT-receptor-ligand
CHEMBL1784957 ACHE Drug Pro-Drug Carbamate Derivative of Rivastigmine Stigmine
6EUL-BY2 BCHE Carbamate Derivative of Rivastigmine Stigmine
RIV-BIMb-5d BCHE Derivative of Rivastigmine Stigmine Carbamate Benzimidazole
Debromoflustramine-B BCHE Natural Pyrrolidine Indole Derivative of physostigmine-eserine Stigmine
Salicylic-donepezil-rivastigmine-5a BCHE Carbamate Derivative of Donepezil Salicylic Derivative of Rivastigmine Stigmine Benzylpiperidine
Bis-Noreseroline ACHE Leaving group Indole Derivative of physostigmine-eserine Stigmine
Cymserine BCHE Derivative of physostigmine-eserine Stigmine Carbamate Indole
Dihydrobenzodioxepine-cymeserine BCHE Derivative of physostigmine-eserine Stigmine Carbamate
Tetrahydrofurobenzofuran-cymserine ACHE Derivative of physostigmine-eserine Stigmine Carbamate Benzofuran
(-)-phenethylcymserine Carb_B_Chordata BCHE ACHE Derivative of physostigmine-eserine Stigmine Carbamate
Cymyl-carbamate-physovenol ACHE Derivative of physostigmine-eserine Stigmine Carbamate
N1-Phenethylnorcymserine BCHE Derivative of physostigmine-eserine Stigmine Carbamate Indole
Bisnorcymserine BCHE ACHE Carbamate Indole Derivative of physostigmine-eserine Stigmine
NAP ACHE Derivative of Rivastigmine Stigmine
Physovenine ACHE Carbamate Natural Indole Derivative of physostigmine-eserine Stigmine
Ganstigmine ACHE Derivative of physostigmine-eserine Stigmine Carbamate Indole Organochlorine
MTR-3 BCHE Derivative of Bambuterol Derivative of Rivastigmine Stigmine Carbamate tert-Butyl
MTR-1 BCHE Derivative of Bambuterol Derivative of Rivastigmine Stigmine Carbamate tert-Butyl
Miotine ACHE Carbamate Derivative of Rivastigmine Stigmine
Rivastigmine ACHE Derivative of Rivastigmine Stigmine Carbamate Drug
Eseroline ACHE Derivative of physostigmine-eserine Stigmine Indole
Geneserine ACHE BCHE Natural Indole Carbamate Derivative of physostigmine-eserine Stigmine Oxazine
Geneseroline Natural Indole Derivative of physostigmine-eserine Stigmine Leaving group Oxazine
Heptylphysostigmine ACHE Derivative of physostigmine-eserine Stigmine Carbamate Indole
MF231 ACHE Derivative of physostigmine-eserine Stigmine Carbamate Morpholine Indole
MF217 ACHE Derivative of physostigmine-eserine Stigmine Carbamate Morpholine Indole
MF268 ACHE Derivative of physostigmine-eserine Stigmine Carbamate Morpholine Indole
Neostigmine~Prostigmine ACHE BCHE Stigmine Derivative of Neostigmine~Prostigmine Carbamate Trimethylammonium Ammonium
Posiphen ACHE Derivative of physostigmine-eserine Stigmine Carbamate Drug Indole
Phenserine ACHE Derivative of physostigmine-eserine Stigmine Carbamate Drug Indole
Physostigmine-methiodide ACHE Derivative of physostigmine-eserine Stigmine Natural_modified Carbamate Indole
Physostigmine~Eserine ACHE BCHE Arylacetamide_deacetylase Derivative of physostigmine-eserine Stigmine Natural Carbamate Drug Indole
Distigmine BCHE Carbamate Stigmine Drug Pyridine
Pyridostigmine BCHE ACHE Carbamate Stigmine Drug Pyridine
Quilostigmine ACHE Derivative of physostigmine-eserine Stigmine Carbamate Isoquinoline Indole
Tolserine ACHE BCHE Derivative of physostigmine-eserine Stigmine Carbamate Indole NTE inhibitor Not AlphaBeta Hydrolase target OPIDN-OP
CHEMBL190322 ACHE BCHE Carbamate Derivative of Rivastigmine Stigmine Chromen Sulfur compound
CHEMBL189907 ACHE BCHE Carbamate Derivative of Rivastigmine Stigmine Indole
CHEMBL274107 ACHE BCHE Carbamate Derivative of Rivastigmine Stigmine Chromen
HY-157437 ACHE BCHE Carbamate Derivative of Tacrine Acridine Alkyl linked bis-ligand Derivative of Rivastigmine Stigmine
RIV-Piperidine-Cpd6a BCHE Piperidine Derivative of Rivastigmine Stigmine Carbamate
MP30 BCHE Multitarget Derivative of Rivastigmine Stigmine Carbamate Antioxidant Sulfur compound
RIV-IND-5b2 ACHE Monoamine-oxidase-inhibitor Multitarget Derivative of Rivastigmine Stigmine Indole anti-Abeta-aggregation Antioxidant
RIV-BIM-4d ACHE Monoamine-oxidase-inhibitor Multitarget Derivative of Rivastigmine Stigmine Benzimidazole
Rivastigmine-Donepezil-COR783 ACHE BCHE Cannabinoid-Receptor-ligand Derivative of Rivastigmine Stigmine Multitarget Sulfur compound Derivative of Donepezil Carbamate Adamantyl
Xanthostigmine ACHE BCHE Stigmine Carbamate Xanthene
Cyclohexylmethylcarbamate-phenethylnorphysostigmine-3u BCHE Derivative of physostigmine-eserine Stigmine Carbamate
TL-1238 BCHE ACHE Derivative of Neostigmine~Prostigmine Stigmine Carbamate Ammonium
S208 BCHE ACHE Derivative of Neostigmine~Prostigmine Stigmine Carbamate Ammonium
Cpd35-Rivastigmine-5-HT6 BCHE Derivative of Rivastigmine Stigmine Multitarget 5-HT-receptor-ligand Sulfur compound Sulfonamide Indole Carbamate Alkyl linked bis-ligand anti-Abeta-aggregation
Idalopirdine-rivastigmine BCHE Drug Pro-Drug Carbamate Derivative of Rivastigmine Stigmine Multitarget 5-HT-receptor-ligand
CHEMBL1784957 ACHE Drug Pro-Drug Carbamate Derivative of Rivastigmine Stigmine
6EUL-BY2 BCHE Carbamate Derivative of Rivastigmine Stigmine
RIV-BIMb-5d BCHE Derivative of Rivastigmine Stigmine Carbamate Benzimidazole
Debromoflustramine-B BCHE Natural Pyrrolidine Indole Derivative of physostigmine-eserine Stigmine
Salicylic-donepezil-rivastigmine-5a BCHE Carbamate Derivative of Donepezil Salicylic Derivative of Rivastigmine Stigmine Benzylpiperidine
Bis-Noreseroline ACHE Leaving group Indole Derivative of physostigmine-eserine Stigmine
Cymserine BCHE Derivative of physostigmine-eserine Stigmine Carbamate Indole
Dihydrobenzodioxepine-cymeserine BCHE Derivative of physostigmine-eserine Stigmine Carbamate
Tetrahydrofurobenzofuran-cymserine ACHE Derivative of physostigmine-eserine Stigmine Carbamate Benzofuran
(-)-phenethylcymserine Carb_B_Chordata BCHE ACHE Derivative of physostigmine-eserine Stigmine Carbamate
Cymyl-carbamate-physovenol ACHE Derivative of physostigmine-eserine Stigmine Carbamate
N1-Phenethylnorcymserine BCHE Derivative of physostigmine-eserine Stigmine Carbamate Indole
Bisnorcymserine BCHE ACHE Carbamate Indole Derivative of physostigmine-eserine Stigmine
NAP ACHE Derivative of Rivastigmine Stigmine
Physovenine ACHE Carbamate Natural Indole Derivative of physostigmine-eserine Stigmine
Ganstigmine ACHE Derivative of physostigmine-eserine Stigmine Carbamate Indole Organochlorine
MTR-3 BCHE Derivative of Bambuterol Derivative of Rivastigmine Stigmine Carbamate tert-Butyl
MTR-1 BCHE Derivative of Bambuterol Derivative of Rivastigmine Stigmine Carbamate tert-Butyl
Miotine ACHE Carbamate Derivative of Rivastigmine Stigmine
Rivastigmine ACHE Derivative of Rivastigmine Stigmine Carbamate Drug
Eseroline ACHE Derivative of physostigmine-eserine Stigmine Indole
Geneserine ACHE BCHE Natural Indole Carbamate Derivative of physostigmine-eserine Stigmine Oxazine
Geneseroline Natural Indole Derivative of physostigmine-eserine Stigmine Leaving group Oxazine
Heptylphysostigmine ACHE Derivative of physostigmine-eserine Stigmine Carbamate Indole
MF231 ACHE Derivative of physostigmine-eserine Stigmine Carbamate Morpholine Indole
MF217 ACHE Derivative of physostigmine-eserine Stigmine Carbamate Morpholine Indole
MF268 ACHE Derivative of physostigmine-eserine Stigmine Carbamate Morpholine Indole
Neostigmine~Prostigmine ACHE BCHE Stigmine Derivative of Neostigmine~Prostigmine Carbamate Trimethylammonium Ammonium
Posiphen ACHE Derivative of physostigmine-eserine Stigmine Carbamate Drug Indole
Phenserine ACHE Derivative of physostigmine-eserine Stigmine Carbamate Drug Indole
Physostigmine-methiodide ACHE Derivative of physostigmine-eserine Stigmine Natural_modified Carbamate Indole
Physostigmine~Eserine ACHE BCHE Arylacetamide_deacetylase Derivative of physostigmine-eserine Stigmine Natural Carbamate Drug Indole
Distigmine BCHE Carbamate Stigmine Drug Pyridine
Pyridostigmine BCHE ACHE Carbamate Stigmine Drug Pyridine
Quilostigmine ACHE Derivative of physostigmine-eserine Stigmine Carbamate Isoquinoline Indole
Tolserine ACHE BCHE Derivative of physostigmine-eserine Stigmine Carbamate Indole NTE inhibitor Not AlphaBeta Hydrolase target OPIDN-OP