MTR-3
elAChE IC50 >100 microM ; eqBChE IC50 0.078 +/- 0.005 microM
General
Type : Derivative of Bambuterol, Derivative of Rivastigmine, Carbamate, tert-Butyl
Chemical_Nomenclature :
Canonical SMILES : C1=C(C=CC=C1C(CN2CCCCC2)O)OC(=O)N(CC)C
InChI : InChI=1S\/C17H26N2O3\/c1-3-18(2)17(21)22-15-9-7-8-14(12-15)16(20)13-19-10-5-4-6-11-19\/h7-9,12,16,20H,3-6,10-11,13H2,1-2H3
InChIKey : WFZQDZBEACPCKC-UHFFFAOYSA-N
Other name(s) :
Target
Families : MTR-3 ligand of proteins in family
BCHE
Protein :
human-BCHE
References (1)
| Title : Rivastigmine-Bambuterol Hybrids as Selective Butyrylcholinesterase Inhibitors - Wu_2023_Molecules_29_ |
| Author(s) : Wu J , Tan Z , Pistolozzi M , Tan W |
| Ref : Molecules , 29 : , 2023 |
| Abstract : |
| PubMedSearch : Wu_2023_Molecules_29_ |
| PubMedID: 38202655 |