Nitrophenyl-methyl-p-biotinamidophenylmethylphosphonate
inhibitor of butyrylcholinesterase, inhibitor of catalytic antibodies
General
Type : Organophosphate, pNP, Sulfur Compound, Biotin derivative
Chemical_Nomenclature : N-[4-[[methoxy-(4-nitrophenoxy)phosphoryl]methyl]phenyl]-5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl)pentanamide
Canonical SMILES : COP(=O)(CC1=CC=C(C=C1)NC(=O)CCCCC2C3C(CS2)NC(=O)N3)OC4=CC=C(C=C4)[N+](=O)[O-] || CO[P](=O)(CC1=CC=C(C=C1)NC(=O)CCCCC2C3C(CS2)NC(=O)N3)CC4=CC=C(C=C4)[N+](=O)[O-]
InChI : InChI=1S\/C24H29N4O7PS\/c1-34-36(33,35-19-12-10-18(11-13-19)28(31)32)14-16-6-8-17(9-7-16)25-22(29)5-3-2-4-21-23-20(15-37-21)26-24(30)27-23\/h6-13,20-21,23H,2-5,14-15H2,1H3,(H,25,29)(H2,26,27,30)
InChIKey : HHUIPFFDTLXXAG-UHFFFAOYSA-N
Other name(s) : Nitrophenyl-methyl-p-biotinamidophenylmethylphosphonate
MW : 548.6
Formula : C24H29N4O7PS
CAS_number :
PubChem : 101099607
UniChem : HHUIPFFDTLXXAG-UHFFFAOYSA-N
Target
Families : Nitrophenyl-methyl-p-biotinamidophenylmethylphosphonate ligand of proteins in family
BCHE
References (2)
| Title : Enzyme mimicry by the antiidiotypic antibody approach - Kolesnikov_2000_Proc.Natl.Acad.Sci.U.S.A_97_13526 |
| Author(s) : Kolesnikov AV , Kozyr AV , Alexandrova ES , Koralewski F , Demin AV , Titov MI , Avalle B , Tramontano A , Paul S , Thomas D , Gabibov AG , Friboulet A |
| Ref : Proc Natl Acad Sci U S A , 97 :13526 , 2000 |
| Abstract : |
| PubMedSearch : Kolesnikov_2000_Proc.Natl.Acad.Sci.U.S.A_97_13526 |
| PubMedID: 11095704 |
| Title : Inhibition and labeling of enzymes and abzymes by phosphonate diesters - Tramontano_2000_Appl.Biochem.Biotechnol_83_233 |
| Author(s) : Tramontano A , Ivanov B , Gololobov G , Paul S |
| Ref : Appl Biochem Biotechnol , 83 :233 , 2000 |
| Abstract : |
| PubMedSearch : Tramontano_2000_Appl.Biochem.Biotechnol_83_233 |
| PubMedID: 10826963 |