Novichok-5~A-232

"Novichok (newcomer/ newbie/ novice, beginner/) is a series of binary chemical weapons developed by the Soviet Union and Russia between 1971 and 1993. Mirzayanov provided the first description of these agents but are somewhat different from the structures identified later"

General

Type : Organophosphate,Chemical Warfare Agent,Novichok

Chemical_Nomenclature : 3-chloro-2-methylpropyl ((chlorofluoromethylene)amino)oxyphosphonofluoridate || (1E)-1-chloro-N-[1-chloropropan-2-yloxy(fluoro)phosphoryl]oxymethanimidoyl fluoride

Canonical SMILES : CC(CCl)OP(=O)(ON=C(F)Cl)F

InChI : InChI=1S\/C4H6Cl2F2NO3P\/c1-3(2-5)11-13(8,10)12-9-4(6)7\/h3H,2H2,1H3\/b9-4-

InChIKey : FOHQFVXLTJEIKH-WTKPLQERSA-N

Other name(s) : A-232,A232,SCHEMBL21981151


MW : 255.97

Formula : C4H6Cl2F2NO3P

CAS_number : 16415-09-1

PubChem : 146586259

UniChem : FOHQFVXLTJEIKH-WTKPLQERSA-N

IUPHAR :

Wikipedia : Novichok_agent

Target

Families : Novichok-5~A-232 ligand of proteins in family: ACHE || BCHE

Stucture :

Protein : human-ACHE

References (3)

Title : Novichok: a murderous nerve agent attack in the UK -
Author(s) : Vale JA , Marrs TO , Maynard RC
Ref : Clinical Toxicology (Phila) , 56 :1093 , 2018
PubMedID: 29757015

Title : Novichok agents: a historical, current, and toxicological perspective - Chai_2018_Toxicol.Commun_2_45
Author(s) : Chai PR , Hayes BD , Erickson TB , Boyer EW
Ref : Toxicol Commun , 2 :45 , 2018
Abstract : Chai_2018_Toxicol.Commun_2_45
ESTHER : Chai_2018_Toxicol.Commun_2_45
PubMedSearch : Chai_2018_Toxicol.Commun_2_45
PubMedID: 30003185

Title : Chemical warfare agent NOVICHOK - mini-review of available data - Nepovimova_2018_Food.Chem.Toxicol_121_343
Author(s) : Nepovimova E , Kuca K
Ref : Food & Chemical Toxicology , 121 :343 , 2018
Abstract : Nepovimova_2018_Food.Chem.Toxicol_121_343
ESTHER : Nepovimova_2018_Food.Chem.Toxicol_121_343
PubMedSearch : Nepovimova_2018_Food.Chem.Toxicol_121_343
PubMedID: 30213549