P-nitrophenol
product of hydrolysis of pNP-esters || Leaving group of paraoxon when inhibiting enzymes. Product of hydrolysis of Esters of 4-Nitrophenol. Amounts of 4-nitrophenol produced by a particular enzyme in the presence of its corresponding substrate can be measured with a spectrophotometer at or around 405 nm and used as a proxy measurement for the amount of the enzyme activity in the sample. Leaving group of NEMP, Methylparaoxon, VXS
General
Chemical_Nomenclature : 4-nitrophenol
Canonical SMILES : C1=CC(=CC=C1[N+](=O)[O-])O
InChI : InChI=1S\/C6H5NO3\/c8-6-3-1-5(2-4-6)7(9)10\/h1-4,8H
InChIKey : BTJIUGUIPKRLHP-UHFFFAOYSA-N
Other name(s) : pNP || NPO || 4-Nitrophenol || P-nitrophenol || Phenol, 4-nitro- || Niphen || Paranitrophenol || Para nitrophenol
MW : 139.11
Formula : C6H5NO3
CAS_number : 100-02-7
PubChem : 980
UniChem : BTJIUGUIPKRLHP-UHFFFAOYSA-N
Target
Families : P-nitrophenol ligand of proteins in family
Polyesterase-lipase-cutinase
Hormone-sensitive_lipase_like
Structure :
9J5A
Protein :
idesa-peth
9bact-H6BDX1
9delt-EstD11
sulad-g8tv28
References (3)
| Title : Mechanistic and structural insights into EstS1 esterase: A potent broad-spectrum phthalate diester degrading enzyme - Verma_2024_Structure__ |
| Author(s) : Verma S , Choudhary S , Amith Kumar K , Mahto JK , Vamsi KA , Mishra I , Prakash VB , Sircar D , Tomar S , Kumar Sharma A , Singla J , Kumar P |
| Ref : Structure , : , 2024 |
| Abstract : |
| PubMedSearch : Verma_2024_Structure__ |
| PubMedID: 39642872 |
| Gene_locus related to this paper: sulad-g8tv28 |
| Title : Biochemical and Structural Characterization of a novel thermophilic esterase EstD11 provide catalytic insights for the HSL family - Miguel-Ruano_2021_Comput.Struct.Biotechnol.J_19_1214 |
| Author(s) : Miguel-Ruano V , Rivera I , Rajkovic J , Knapik K , Torrado A , Otero JM , Beneventi E , Becerra M , Sanchez-Costa M , Hidalgo A , Berenguer J , Gonzalez-Siso MI , Cruces J , Rua ML , Hermoso JA |
| Ref : Comput Struct Biotechnol J , 19 :1214 , 2021 |
| Abstract : |
| PubMedSearch : Miguel-Ruano_2021_Comput.Struct.Biotechnol.J_19_1214 |
| PubMedID: 33680362 |
| Gene_locus related to this paper: 9delt-EstD11 |
| Title : Structural insights of a hormone sensitive lipase homologue Est22 - Huang_2016_Sci.Rep_6_28550 |
| Author(s) : Huang J , Huo YY , Ji R , Kuang S , Ji C , Xu XW , Li J |
| Ref : Sci Rep , 6 :28550 , 2016 |
| Abstract : |
| PubMedSearch : Huang_2016_Sci.Rep_6_28550 |
| PubMedID: 27328716 |
| Gene_locus related to this paper: 9bact-H6BDX1 |