Pentagalloylglucose

General

Type : Derivative of Gallate, Natural, Polyphenol

Chemical_Nomenclature : [(2R,3R,4S,5R,6S)-3,4,5,6-tetrakis[(3,4,5-trihydroxybenzoyl)oxy]oxan-2-yl]methyl 3,4,5-trihydroxybenzoate

Canonical SMILES : C1=C(C=C(C(=C1O)O)O)C(=O)OCC2C(C(C(C(O2)OC(=O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O)OC(=O)C5=CC(=C(C(=C5)O)O)O)OC(=O)C6=CC(=C(C(=C6)O)O)O

InChI : InChI=1S\/C41H32O26\/c42-17-1-12(2-18(43)28(17)52)36(57)62-11-27-33(64-37(58)13-3-19(44)29(53)20(45)4-13)34(65-38(59)14-5-21(46)30(54)22(47)6-14)35(66-39(60)15-7-23(48)31(55)24(49)8-15)41(63-27)67-40(61)16-9-25(50)32(56)26(51)10-16\/h1-10,27,33-35,41-56H,11H2\/t27-,33-,34+,35-,41+\/m1\/s1

InChIKey : QJYNZEYHSMRWBK-NIKIMHBISA-N

Other name(s) : PGG  ||  1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose  ||  Pentagalloyl glucose  ||  1,2,3,4,6-Pentagalloylglucose


MW : 940.7

Formula : C41H32O26

CAS_number : 14937-32-7

PubChem : 65238

UniChem : QJYNZEYHSMRWBK-NIKIMHBISA-N

Target

Families : Pentagalloylglucose ligand of proteins in family
Pancreatic_lipase

Protein :
human-PNLIP

References (2)

Title : Discovery of human pancreatic lipase inhibitors from root of Rhodiola crenulata via integrating bioactivity-guided fractionation, chemical profiling and biochemical assay - Ma_2022_J.Pharm.Anal_12_683
Author(s) : Ma LJ , Hou XD , Qin XY , He RJ , Yu HN , Hu Q , Guan XQ , Jia SN , Hou J , Lei T , Ge GB
Ref : J Pharm Anal , 12 :683 , 2022
Abstract :
PubMedSearch : Ma_2022_J.Pharm.Anal_12_683
PubMedID: 36105167

Title : Pancreatic lipase inhibitory gallotannins from Galla Rhois with inhibitory effects on adipocyte differentiation in 3T3-L1 cells - Kwon_2013_Molecules_18_10629
Author(s) : Kwon OJ , Bae JS , Lee HY , Hwang JY , Lee EW , Ito H , Kim TH
Ref : Molecules , 18 :10629 , 2013
Abstract :
PubMedSearch : Kwon_2013_Molecules_18_10629
PubMedID: 24002138