| Title : Discovery of human pancreatic lipase inhibitors from root of Rhodiola crenulata via integrating bioactivity-guided fractionation, chemical profiling and biochemical assay - Ma_2022_J.Pharm.Anal_12_683 |
| Author(s) : Ma LJ , Hou XD , Qin XY , He RJ , Yu HN , Hu Q , Guan XQ , Jia SN , Hou J , Lei T , Ge GB |
| Ref : J Pharm Anal , 12 :683 , 2022 |
| Abstract : |
| PubMedSearch : Ma_2022_J.Pharm.Anal_12_683 |
| PubMedID: 36105167 |
| Title : Design, Synthesis, and Structure-Activity Relationship Study of Pyrazolones as Potent Inhibitors against Pancreatic Lipase - Bao_2021_ChemMedChem__ |
| Author(s) : Bao X , Zhang J , Yang Y , Qian XK , Song PF , Zhao YS , Guan XQ , Zou LW , Wang H |
| Ref : ChemMedChem , : , 2021 |
| Abstract : |
| PubMedSearch : Bao_2021_ChemMedChem__ |
| PubMedID: 33527731 |
| Title : Discovery of pyrazolones as novel carboxylesterase 2 inhibitors that potently inhibit the adipogenesis in cells - Qian_2021_Bioorg.Med.Chem_40_116187 |
| Author(s) : Qian XK , Zhang J , Song PF , Zhao YS , Ma HY , Jin Q , Wang DD , Guan XQ , Li SY , Bao X , Zou LW |
| Ref : Bioorganic & Medicinal Chemistry , 40 :116187 , 2021 |
| Abstract : |
| PubMedSearch : Qian_2021_Bioorg.Med.Chem_40_116187 |
| PubMedID: 33965840 |
| Title : Rapalogues as hCES2A Inhibitors: In Vitro and In Silico Investigations - Shi_2021_Eur.J.Drug.Metab.Pharmacokinet_46_129 |
| Author(s) : Shi CC , Song YQ , He RJ , Guan XQ , Song LL , Chen ST , Sun MR , Ge GB , Zhang LR |
| Ref : Eur J Drug Metab Pharmacokinet , 46 :129 , 2021 |
| Abstract : |
| PubMedSearch : Shi_2021_Eur.J.Drug.Metab.Pharmacokinet_46_129 |
| PubMedID: 33140264 |
| Gene_locus related to this paper: human-CES2 |
| Title : Discovery and Characterization of the Biflavones From Ginkgo biloba as Highly Specific and Potent Inhibitors Against Human Carboxylesterase 2 - Song_2021_Front.Pharmacol_12_655659 |
| Author(s) : Song YQ , He RJ , Pu D , Guan XQ , Shi JH , Li YG , Hou J , Jia SN , Qin WW , Fang SQ , Ge GB |
| Ref : Front Pharmacol , 12 :655659 , 2021 |
| Abstract : |
| PubMedSearch : Song_2021_Front.Pharmacol_12_655659 |
| PubMedID: 34084136 |
| Gene_locus related to this paper: human-CES2 |
| Title : Discovery of hCES2A inhibitors from Glycyrrhiza inflata via combination of docking-based virtual screening and fluorescence-based inhibition assays - Song_2021_Food.Funct_12_162 |
| Author(s) : Song YQ , Guan XQ , Weng ZM , Liu JL , Chen J , Wang L , Cui LT , Fang SQ , Hou J , Ge GB |
| Ref : Food Funct , 12 :162 , 2021 |
| Abstract : |
| PubMedSearch : Song_2021_Food.Funct_12_162 |
| PubMedID: 33291124 |
| Title : Design, synthesis and biological evaluation of indanone-chalcone hybrids as potent and selective hCES2A inhibitors - Huo_2020_Eur.J.Med.Chem_209_112856 |
| Author(s) : Huo PC , Guan XQ , Liu P , Song YQ , Sun MR , He RJ , Zou LW , Xue LJ , Shi JH , Zhang N , Liu ZG , Ge GB |
| Ref : Eur Journal of Medicinal Chemistry , 209 :112856 , 2020 |
| Abstract : |
| PubMedSearch : Huo_2020_Eur.J.Med.Chem_209_112856 |
| PubMedID: 33007602 |
| Title : Design, synthesis and biological evaluation of novel chalcone-like compounds as potent and reversible pancreatic lipase inhibitors - Huo_2020_Bioorg.Med.Chem__115853 |
| Author(s) : Huo PC , Hu Q , Shu S , Zhou QH , He RJ , Hou J , Guan XQ , Tu DZ , Hou XD , Liu P , Zhang N , Liu ZG , Ge GB |
| Ref : Bioorganic & Medicinal Chemistry , :115853 , 2020 |
| Abstract : |
| PubMedSearch : Huo_2020_Bioorg.Med.Chem__115853 |
| PubMedID: 33214035 |
| Gene_locus related to this paper: human-PNLIP |
| Title : Inhibition of pancreatic lipase by the constituents in St. John's Wort: In vitro and in silico investigations - Hou_2020_Int.J.Biol.Macromol_145_620 |
| Author(s) : Hou XD , Guan XQ , Cao YF , Weng ZM , Hu Q , Liu HB , Jia SN , Zang SZ , Zhou Q , Yang L , Ge GB , Hou J |
| Ref : Int J Biol Macromol , 145 :620 , 2020 |
| Abstract : |
| PubMedSearch : Hou_2020_Int.J.Biol.Macromol_145_620 |
| PubMedID: 31883893 |
| Gene_locus related to this paper: human-PNLIP |
| Title : Bioluminescent Sensor Reveals that Carboxylesterase 1A is a Novel Endoplasmic Reticulum-Derived Serologic Indicator for Hepatocyte Injury - Wang_2020_ACS.Sens_5_1987 |
| Author(s) : Wang DD , Zou LW , Jin Q , Guan XQ , Yu Y , Zhu YD , Huang J , Gao P , Wang P , Ge GB , Yang L |
| Ref : ACS Sens , 5 :1987 , 2020 |
| Abstract : |
| PubMedSearch : Wang_2020_ACS.Sens_5_1987 |
| PubMedID: 32529833 |
| Title : Pancreatic Lipase Inhibitory Cyclohexapeptides from the Marine Sponge-Derived Fungus Aspergillus sp. 151304 - Tang_2020_J.Nat.Prod_83_2287 |
| Author(s) : Tang WZ , Liu JT , Hu Q , He RJ , Guan XQ , Ge GB , Han H , Yang F , Lin HW |
| Ref : Journal of Natural Products , 83 :2287 , 2020 |
| Abstract : |
| PubMedSearch : Tang_2020_J.Nat.Prod_83_2287 |
| PubMedID: 32662266 |
| Title : Discovery of natural alkaloids as potent and selective inhibitors against human carboxylesterase 2 - Zhao_2020_Bioorg.Chem_105_104367 |
| Author(s) : Zhao YS , Qian XK , Guan XQ , Song PF , Song YQ , He RJ , Sun MR , Wang XY , Zou LW , Ge GB |
| Ref : Bioorg Chem , 105 :104367 , 2020 |
| Abstract : |
| PubMedSearch : Zhao_2020_Bioorg.Chem_105_104367 |
| PubMedID: 33080495 |
| Title : Pentacyclic triterpenoid acids in Styrax as potent and highly specific inhibitors against human carboxylesterase 1A - Wang_2020_Food.Funct_11_8680 |
| Author(s) : Wang L , Guan XQ , He RJ , Qin WW , Xiong Y , Zhang F , Song YQ , Huo PC , Song PF , Tang H , Ge GB |
| Ref : Food Funct , 11 :8680 , 2020 |
| Abstract : |
| PubMedSearch : Wang_2020_Food.Funct_11_8680 |
| PubMedID: 32940318 |
| Title : Discovery of a highly specific and efficacious inhibitor of human carboxylesterase 2 by large-scale screening - Song_2019_Int.J.Biol.Macromol_137_261 |
| Author(s) : Song YQ , Guan XQ , Weng ZM , Wang YQ , Chen J , Jin Q , Fang SQ , Fan B , Cao YF , Hou J , Ge GB |
| Ref : Int J Biol Macromol , 137 :261 , 2019 |
| Abstract : |
| PubMedSearch : Song_2019_Int.J.Biol.Macromol_137_261 |
| PubMedID: 31260759 |