Z-Pro-Prolinal-IC2
General
Type : Benzyloxycarbonyl, Pyrrolidine, Peptide, Carboxamide
Chemical_Nomenclature : (5R)-N-benzyl-5-[(2S)-2-[(1R)-1,2-dihydroxyethyl]pyrrolidine-1-carbonyl]cyclopentene-1-carboxamide
Canonical SMILES : C1CC(N(C1)C(=O)C2CCC=C2C(=O)NCC3=CC=CC=C3)C(CO)O
InChI : InChI=1S\/C20H26N2O4\/c23-13-18(24)17-10-5-11-22(17)20(26)16-9-4-8-15(16)19(25)21-12-14-6-2-1-3-7-14\/h1-3,6-8,16-18,23-24H,4-5,9-13H2,(H,21,25)\/t16-,17+,18+\/m1\/s1
InChIKey : YWYIBAJVRQWUCG-SQNIBIBYSA-N
Other name(s) : IC2 || 2P4
MW : 358.43
Formula : C20H26N2O4
CAS_number :
PubChem : 72200811
UniChem : YWYIBAJVRQWUCG-SQNIBIBYSA-N
Target
Families : Z-Pro-Prolinal-IC2 ligand of proteins in family
S9N_PPCE_Peptidase_S9
Structure :
4AMZ
Protein :
pig-ppce
References (1)
| Title : Molecular dynamics, crystallography and mutagenesis studies on the substrate gating mechanism of prolyl oligopeptidase. - Kaszuba_2012_Biochimie_94_1398 |
| Author(s) : Kaszuba K , Rog T , Danne R , Canning P , Fulop V , Juhasz T , Szeltner Z , St Pierre JF , Garcia-Horsman A , Mannisto PT , Karttunen M , Hokkanen J , Bunker A |
| Ref : Biochimie , 94 :1398 , 2012 |
| Abstract : |
| PubMedSearch : Kaszuba_2012_Biochimie_94_1398 |
| PubMedID: 22484394 |
| Gene_locus related to this paper: pig-ppce |