diEt-PFP

General

Type : Organophosphate

Chemical_Nomenclature : diethyl 1,1,1,3,3,3-hexafluoropropan-2-yl phosphate

Canonical SMILES : CCOP(=O)(OCC)OC(C(F)(F)F)C(F)(F)F

InChI : InChI=1S\/C7H11F6O4P\/c1-3-15-18(14,16-4-2)17-5(6(8,9)10)7(11,12)13\/h5H,3-4H2,1-2H3

InChIKey : YEMNWQQLKIIPRQ-UHFFFAOYSA-N

Other name(s) : ZINC05718302  ||  Phosphoric acid diethyl=1-(trifluoromethyl)-2,2,2-trifluoroethyl ester  ||  2-diethoxyphosphoryloxy-1,1,1,3,3,3-hexafluoro-propane


MW : 304.12

Formula : C7H11F6O4P

CAS_number :

PubChem : 12513073

UniChem : YEMNWQQLKIIPRQ-UHFFFAOYSA-N

Target

Families : diEt-PFP ligand of proteins in family
ACHE BCHE

References (2)

Title : Synthesis of organophosphates with fluorine-containing leaving groups as serine esterase inhibitors with potential for Alzheimer disease therapeutics - Makhaeva_2009_Bioorg.Med.Chem.Lett_19_5528
Author(s) : Makhaeva GF , Aksinenko AY , Sokolov VB , Serebryakova OG , Richardson RJ
Ref : Bioorganic & Medicinal Chemistry Lett , 19 :5528 , 2009
Abstract :
PubMedSearch : Makhaeva_2009_Bioorg.Med.Chem.Lett_19_5528
PubMedID: 19717305

Title : Esterase profile and analysis of structure-inhibitor selectivity relationships for homologous phosphorylated 1-hydroperfluoroisopropanols -
Author(s) : Makhaeva GF , Serebryakova OG , Boltneva NP , Galenko TG , Aksinenko AY , Sokolov VB , Martynov IV
Ref : Dokl Biochem Biophys , 423 :352 , 2008
PubMedID: 19230387