Richardson RJ

General

Full name : Richardson Rudy J

First name : Rudy J

Mail : Toxicology Research Training Program\; University of Michigan\; 1420 Washington Heights\; Ann Arbor\; Michigan 48109-2029

Zip Code : 48109-2029

City : Ann Arbor

Country : USA

Email : rjrich@umich.edu

Phone : +17349360769

Fax :

Website : \/\/sph.umich.edu\/faculty-profiles\/richardson-rudy.html

Directory :

References (72)

Title : Combining Experimental and Computational Methods to Produce Conjugates of Anticholinesterase and Antioxidant Pharmacophores with Linker Chemistries Affecting Biological Activities Related to Treatment of Alzheimer's Disease - Makhaeva_2024_Molecules_29_321
Author(s) : Makhaeva GF , Kovaleva NV , Rudakova EV , Boltneva NP , Lushchekina SV , Astakhova TY , Timokhina EN , Serkov IV , Proshin AN , Soldatova YV , Poletaeva DA , Faingold, II , Mumyatova VA , Terentiev AA , Radchenko EV , Palyulin VA , Bachurin SO , Richardson RJ
Ref : Molecules , 29 :321 , 2024
PubMedID: 38257233

Title : Derivatives of 9-phosphorylated acridine as butyrylcholinesterase inhibitors with antioxidant activity and the ability to inhibit beta-amyloid self-aggregation: potential therapeutic agents for Alzheimer's disease - Makhaeva_2023_Front.Pharmacol_14_1219980
Author(s) : Makhaeva GF , Kovaleva NV , Rudakova EV , Boltneva NP , Lushchekina SV , Astakhova TY , Timokhina EN , Serebryakova OG , Shchepochkin AV , Averkov MA , Utepova IA , Demina NS , Radchenko EV , Palyulin VA , Fisenko VP , Bachurin SO , Chupakhin ON , Charushin VN , Richardson RJ
Ref : Front Pharmacol , 14 :1219980 , 2023
PubMedID: 37654616

Title : Conjugates of Tacrine and Salicylic Acid Derivatives as New Promising Multitarget Agents for Alzheimer's Disease - Makhaeva_2023_Int.J.Mol.Sci_24_2285
Author(s) : Makhaeva GF , Kovaleva NV , Rudakova EV , Boltneva NP , Grishchenko MV , Lushchekina SV , Astakhova TY , Serebryakova OG , Timokhina EN , Zhilina EF , Shchegolkov EV , Ulitko MV , Radchenko EV , Palyulin VA , Burgart YV , Saloutin VI , Bachurin SO , Richardson RJ
Ref : Int J Mol Sci , 24 :2285 , 2023
PubMedID: 36768608

Title : New Multifunctional Agents for Potential Alzheimer's Disease Treatment Based on Tacrine Conjugates with 2-Arylhydrazinylidene-1,3-Diketones - Elkina_2022_Biomolecules_12_
Author(s) : Elkina NA , Grishchenko MV , Shchegolkov EV , Makhaeva GF , Kovaleva NV , Rudakova EV , Boltneva NP , Lushchekina SV , Astakhova TY , Radchenko EV , Palyulin VA , Zhilina EF , Perminova AN , Lapshin LS , Burgart YV , Saloutin VI , Richardson RJ
Ref : Biomolecules , 12 : , 2022
PubMedID: 36358901

Title : Conjugates of Methylene Blue with Cycloalkaneindoles as New Multifunctional Agents for Potential Treatment of Neurodegenerative Disease - Bachurin_2022_Int.J.Mol.Sci_23_
Author(s) : Bachurin SO , Shevtsova EF , Makhaeva GF , Aksinenko AY , Grigoriev VV , Goreva TV , Epishina TA , Kovaleva NV , Boltneva NP , Lushchekina SV , Rudakova EV , Vinogradova DV , Shevtsov PN , Pushkareva EA , Dubova LG , Serkova TP , Veselov IM , Fisenko VP , Richardson RJ
Ref : Int J Mol Sci , 23 : , 2022
PubMedID: 36430413

Title : Bis-Amiridines as Acetylcholinesterase and Butyrylcholinesterase Inhibitors: N-Functionalization Determines the Multitarget Anti-Alzheimer's Activity Profile - Makhaeva_2022_Molecules_27_
Author(s) : Makhaeva GF , Kovaleva NV , Boltneva NP , Rudakova EV , Lushchekina SV , Astakhova TY , Serkov IV , Proshin AN , Radchenko EV , Palyulin VA , Korabecny J , Soukup O , Bachurin SO , Richardson RJ
Ref : Molecules , 27 : , 2022
PubMedID: 35164325

Title : Conjugates of Tacrine with Salicylamide as Promising Multitarget Agents for Alzheimer's Disease - Grishchenko_2022_ChemMedChem__e202200080
Author(s) : Grishchenko MV , Makhaeva GF , Burgart YV , Rudakova EV , Boltneva NP , Kovaleva NV , Serebryakova OG , Lushchekina SV , Astakhova TY , Zhilina EF , Shchegolkov EV , Richardson RJ , Saloutin VI
Ref : ChemMedChem , :e202200080 , 2022
PubMedID: 35322571

Title : Amiridine-piperazine hybrids as cholinesterase inhibitors and potential multitarget agents for Alzheimer's disease treatment - Makhaeva_2021_Bioorg.Chem_112_104974
Author(s) : Makhaeva GF , Lushchekina SV , Kovaleva NV , Yu Astakhova T , Boltneva NP , Rudakova EV , Serebryakova OG , Proshin AN , Serkov IV , Trofimova TP , Tafeenko VA , Radchenko EV , Palyulin VA , Fisenko VP , Korabecny J , Soukup O , Richardson RJ
Ref : Bioorg Chem , 112 :104974 , 2021
PubMedID: 34029971

Title : Novel potent bifunctional carboxylesterase inhibitors based on a polyfluoroalkyl-2-imino-1,3-dione scaffold - Makhaeva_2021_Eur.J.Med.Chem_218_113385
Author(s) : Makhaeva GF , Lushchekina SV , Boltneva NP , Serebryakova OG , Kovaleva NV , Rudakova EV , Elkina NA , Shchegolkov EV , Burgart YV , Stupina TS , Terentiev AA , Radchenko EV , Palyulin VA , Saloutin VI , Bachurin SO , Richardson RJ
Ref : Eur Journal of Medicinal Chemistry , 218 :113385 , 2021
PubMedID: 33831780

Title : Conjugation of Aminoadamantane and gamma-Carboline Pharmacophores Gives Rise to Unexpected Properties of Multifunctional Ligands - Bachurin_2021_Molecules_26_
Author(s) : Bachurin SO , Makhaeva GF , Shevtsova EF , Aksinenko AY , Grigoriev VV , Shevtsov PN , Goreva TV , Epishina TA , Kovaleva NV , Pushkareva EA , Boltneva NP , Lushchekina SV , Gabrelyan AV , Zamoyski VL , Dubova LG , Rudakova EV , Fisenko VP , Bovina EV , Richardson RJ
Ref : Molecules , 26 : , 2021
PubMedID: 34576998

Title : Neuropathy target esterase (NTE\/PNPLA6) and organophosphorus compound-induced delayed neurotoxicity (OPIDN) - Richardson_2020_Adv.Neurotoxicol_4_1
Author(s) : Richardson RJ , Fink JK , Glynn P , Hufnagel RB , Makhaeva GF , Wijeyesakere SJ
Ref : Adv Neurotoxicol , 4 :1 , 2020
PubMedID: 32518884

Title : New Multifunctional Agents Based on Conjugates of 4-Amino-2,3-polymethylenequinoline and Butylated Hydroxytoluene for Alzheimer's Disease Treatment - Makhaeva_2020_Molecules_25_5891
Author(s) : Makhaeva GF , Kovaleva NV , Rudakova EV , Boltneva NP , Lushchekina SV , Faingold, II , Poletaeva DA , Soldatova YV , Kotelnikova RA , Serkov IV , Ustinov AK , Proshin AN , Radchenko EV , Palyulin VA , Richardson RJ
Ref : Molecules , 25 :5891 , 2020
PubMedID: 33322783

Title : Inhibition of Acetylcholinesterases by Stereoisomeric Organophosphorus Compounds Containing Both Thioester and p-Nitrophenyl Leaving Groups - Talley_2020_Chem.Res.Toxicol_33_2455
Author(s) : Talley TT , Chao CK , Berkman CE , Richardson RJ , Thompson CM
Ref : Chemical Research in Toxicology , 33 :2455 , 2020
PubMedID: 32833441

Title : New Hybrids of 4-Amino-2,3-polymethylene-quinoline and p-Tolylsulfonamide as Dual Inhibitors of Acetyl- and Butyrylcholinesterase and Potential Multifunctional Agents for Alzheimer's Disease Treatment - Makhaeva_2020_Molecules_25_3915
Author(s) : Makhaeva GF , Kovaleva NV , Boltneva NP , Lushchekina SV , Astakhova TY , Rudakova EV , Proshin AN , Serkov IV , Radchenko EV , Palyulin VA , Bachurin SO , Richardson RJ
Ref : Molecules , 25 :3915 , 2020
PubMedID: 32867324

Title : Overview of novel multifunctional agents based on conjugates of gamma-carbolines, carbazoles, tetrahydrocarbazoles, phenothiazines, and aminoadamantanes for treatment of Alzheimer's disease - Makhaeva_2019_Chem.Biol.Interact_13ChEPon_308_224
Author(s) : Makhaeva GF , Shevtsova EF , Boltneva NP , Lushchekina SV , Kovaleva NV , Rudakova EV , Bachurin SO , Richardson RJ
Ref : Chemico-Biological Interactions , 308 :224 , 2019
PubMedID: 31100279

Title : Conjugates of methylene blue with gamma-carboline derivatives as new multifunctional agents for the treatment of neurodegenerative diseases - Bachurin_2019_Sci.Rep_9_4873
Author(s) : Bachurin SO , Makhaeva GF , Shevtsova EF , Boltneva NP , Kovaleva NV , Lushchekina SV , Rudakova EV , Dubova LG , Vinogradova DV , Sokolov VB , Aksinenko AY , Fisenko VP , Richardson RJ , Aliev G
Ref : Sci Rep , 9 :4873 , 2019
PubMedID: 30890752

Title : Synthesis of 2-arylhydrazinylidene-3-oxo-4,4,4-trifluorobutanoic acids as new selective carboxylesterase inhibitors and radical scavengers - Khudina_2019_Bioorg.Med.Chem.Lett__126716
Author(s) : Khudina OG , Makhaeva GF , Elkina NA , Boltneva NP , Serebryakova OG , Shchegolkov EV , Rudakova EV , Lushchekina SV , Burgart YV , Bachurin SO , Richardson RJ , Saloutin VI
Ref : Bioorganic & Medicinal Chemistry Lett , :126716 , 2019
PubMedID: 31640885

Title : Synthesis, molecular docking, and biological evaluation of 3-oxo-2-tolylhydrazinylidene-4,4,4-trifluorobutanoates bearing higher and natural alcohol moieties as new selective carboxylesterase inhibitors - Makhaeva_2019_Bioorg.Chem_91_103097
Author(s) : Makhaeva GF , Elkina NA , Shchegolkov EV , Boltneva NP , Lushchekina SV , Serebryakova OG , Rudakova EV , Kovaleva NV , Radchenko EV , Palyulin VA , Burgart YV , Saloutin VI , Bachurin SO , Richardson RJ
Ref : Bioorg Chem , 91 :103097 , 2019
PubMedID: 31323527

Title : Conjugates of tacrine and 1,2,4-thiadiazole derivatives as new potential multifunctional agents for Alzheimer's disease treatment: Synthesis, quantum-chemical characterization, molecular docking, and biological evaluation - Makhaeva_2019_Bioorg.Chem__103387
Author(s) : Makhaeva GF , Kovaleva NV , Boltneva NP , Lushchekina SV , Rudakova EV , Stupina TS , Terentiev AA , Serkov IV , Proshin AN , Radchenko EV , Palyulin VV , Bachurin SO , Richardson RJ
Ref : Bioorg Chem , :103387 , 2019
PubMedID: 31735356

Title : Synthesis, molecular docking, and biological activity of 2-vinyl chromones: Toward selective butyrylcholinesterase inhibitors for potential Alzheimer's disease therapeutics - Makhaeva_2018_Bioorg.Med.Chem_26_4716
Author(s) : Makhaeva GF , Boltneva NP , Lushchekina SV , Rudakova EV , Serebryakova OG , Kulikova LN , Beloglazkin AA , Borisov RS , Richardson RJ
Ref : Bioorganic & Medicinal Chemistry , 26 :4716 , 2018
PubMedID: 30104121

Title : 9-Substituted acridine derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors possessing antioxidant activity for Alzheimer's disease treatment - Makhaeva_2017_Bioorg.Med.Chem_25_5981
Author(s) : Makhaeva GF , Lushchekina SV , Boltneva NP , Serebryakova OG , Rudakova EV , Ustyugov AA , Bachurin SO , Shchepochkin AV , Chupakhin ON , Charushin VN , Richardson RJ
Ref : Bioorganic & Medicinal Chemistry , 25 :5981 , 2017
PubMedID: 28986116

Title : Synthesis, molecular docking, and biological activity of polyfluoroalkyl dihydroazolo[5,1-c][1,2,4]triazines as selective carboxylesterase inhibitors - Shchegol'kov_2017_Bioorg.Med.Chem_25_3997
Author(s) : Shchegol'kov EV , Makhaeva GF , Boltneva NP , Lushchekina SV , Serebryakova OG , Rudakova EV , Kovaleva NV , Burgart YV , Saloutin VI , Chupakhin ON , Bachurin SO , Richardson RJ
Ref : Bioorganic & Medicinal Chemistry , 25 :3997 , 2017
PubMedID: 28578994

Title : Esterase profiles of organophosphorus compounds in vitro predict their behavior in vivo - Makhaeva_2016_Chem.Biol.Interact_259_332
Author(s) : Makhaeva GF , Rudakova EV , Serebryakova OG , Aksinenko AY , Lushchekina SV , Bachurin SO , Richardson RJ
Ref : Chemico-Biological Interactions , 259 :332 , 2016
PubMedID: 27154493

Title : Synthesis, molecular docking and biological evaluation of N,N-disubstituted 2-aminothiazolines as a new class of butyrylcholinesterase and carboxylesterase inhibitors - Makhaeva_2016_Bioorg.Med.Chem_24_1050
Author(s) : Makhaeva GF , Boltneva NP , Lushchekina SV , Serebryakova OG , Stupina TS , Terentiev AA , Serkov IV , Proshin AN , Bachurin SO , Richardson RJ
Ref : Bioorganic & Medicinal Chemistry , 24 :1050 , 2016
PubMedID: 26827140

Title : Neuropathy target esterase in mouse whole blood as a biomarker of exposure to neuropathic organophosphorus compounds - Makhaeva_2016_J.Appl.Toxicol_36_1468
Author(s) : Makhaeva GF , Rudakova EV , Sigolaeva LV , Kurochkin IN , Richardson RJ
Ref : J Appl Toxicol , 36 :1468 , 2016
PubMedID: 26970094

Title : A review of epidemiologic studies of low-level exposures to organophosphorus insecticides in non-occupational populations - Reiss_2015_Crit.Rev.Toxicol_45_531
Author(s) : Reiss R , Chang ET , Richardson RJ , Goodman M
Ref : Crit Rev Toxicol , 45 :531 , 2015
PubMedID: 26153436

Title : Neuropathy target esterase impairments cause Oliver-McFarlane and Laurence-Moon syndromes - Hufnagel_2015_J.Med.Genet_52_85
Author(s) : Hufnagel RB , Arno G , Hein ND , Hersheson J , Prasad M , Anderson Y , Krueger LA , Gregory LC , Stoetzel C , Jaworek TJ , Hull S , Li A , Plagnol V , Willen CM , Morgan TM , Prows CA , Hegde RS , Riazuddin S , Grabowski GA , Richardson RJ , Dieterich K , Huang T , Revesz T , Martinez-Barbera JP , Sisk RA , Jefferies C , Houlden H , Dattani MT , Fink JK , Dollfus H , Moore AT , Ahmed ZM
Ref : Journal of Medical Genetics , 52 :85 , 2015
PubMedID: 25480986

Title : Further studies toward a mouse model for biochemical assessment of neuropathic potential of organophosphorus compounds - Makhaeva_2014_J.Appl.Toxicol_34_1426
Author(s) : Makhaeva GF , Rudakova EV , Hein ND , Serebryakova OG , Kovaleva NV , Boltneva NP , Fink JK , Richardson RJ
Ref : J Appl Toxicol , 34 :1426 , 2014
PubMedID: 24395470

Title : Effects of occupational exposure to chlorpyrifos on neuropsychological function: A prospective longitudinal study - Berent_2014_Neurotoxicol_41C_44
Author(s) : Berent S , Giordani B , Albers JW , Garabrant DH , Cohen SS , Garrison RP , Richardson RJ
Ref : Neurotoxicology , 41C :44 , 2014
PubMedID: 24447827

Title : Crystal Structure of Patatin-17 in Complex with Aged and Non-Aged Organophosphorus Compounds - Wijeyesakere_2014_PLoS.One_9_e108245
Author(s) : Wijeyesakere SJ , Richardson RJ , Stuckey JA
Ref : PLoS ONE , 9 :e108245 , 2014
PubMedID: 25248161

Title : Neuropathy target esterase (NTE): overview and future - Richardson_2013_Chem.Biol.Interact_203_238
Author(s) : Richardson RJ , Hein ND , Wijeyesakere SJ , Fink JK , Makhaeva GF
Ref : Chemico-Biological Interactions , 203 :238 , 2013
PubMedID: 23220002

Title : Organophosphorus compound esterase profiles as predictors of therapeutic and toxic effects - Makhaeva_2013_Chem.Biol.Interact_203_231
Author(s) : Makhaeva GF , Radchenko EV , Palyulin VA , Rudakova EV , Aksinenko AY , Sokolov VB , Zefirov NS , Richardson RJ
Ref : Chemico-Biological Interactions , 203 :231 , 2013
PubMedID: 23123251

Title : Kinetics and mechanism of inhibition of serine esterases by fluorinated carbethoxy 1-aminophosphonates -
Author(s) : Makhaeva GF , Lushchekina SV , Serebryakova OG , Aksinenko AY , Goreva TV , Richardson RJ , Martynov IV
Ref : Dokl Biochem Biophys , 451 :203 , 2013
PubMedID: 23975401

Title : Combined QSAR studies of inhibitor properties of O-phosphorylated oximes toward serine esterases involved in neurotoxicity, drug metabolism and Alzheimer's disease - Makhaeva_2012_SAR.QSAR.Environ.Res_23_627
Author(s) : Makhaeva GF , Radchenko EV , Baskin II , Palyulin VA , Richardson RJ , Zefirov NS
Ref : SAR QSAR Environ Research , 23 :627 , 2012
PubMedID: 22587543

Title : Esterase profile of O-phosphorylated ethyltrifluorolactates in prediction of their therapeutic and toxic effects -
Author(s) : Rudakova EV , Makhaeva GF , Galenko TG , Aksinenko AY , Sokolov VB , Richardson RJ , Martynov IV
Ref : Dokl Biochem Biophys , 443 :81 , 2012
PubMedID: 22562631

Title : Biosensor analysis of blood esterases for organophosphorus compounds exposure assessment: approaches to simultaneous determination of several esterases - Sigolaeva_2010_Chem.Biol.Interact_187_312
Author(s) : Sigolaeva LV , Makhaeva GF , Rudakova EV , Boltneva NP , Porus M , Dubacheva G , Eremenko A , Kurochkin I , Richardson RJ
Ref : Chemico-Biological Interactions , 187 :312 , 2010
PubMedID: 20097186

Title : Kinetics and mechanism of inhibition of serine esterases by fluorinated aminophosphonates - Makhaeva_2010_Chem.Biol.Interact_187_177
Author(s) : Makhaeva GF , Aksinenko AY , Sokolov VB , Baskin, II , Palyulin VA , Zefirov NS , Hein ND , Kampf JW , Wijeyesakere SJ , Richardson RJ
Ref : Chemico-Biological Interactions , 187 :177 , 2010
PubMedID: 20035729

Title : Paraoxonase status and plasma butyrylcholinesterase activity in chlorpyrifos manufacturing workers - Albers_2010_J.Expo.Sci.Environ.Epidemiol_20_79
Author(s) : Albers JW , Garabrant DH , Berent S , Richardson RJ
Ref : J Expo Sci Environ Epidemiol , 20 :79 , 2010
PubMedID: 19223938

Title : Synthesis of organophosphates with fluorine-containing leaving groups as serine esterase inhibitors with potential for Alzheimer disease therapeutics - Makhaeva_2009_Bioorg.Med.Chem.Lett_19_5528
Author(s) : Makhaeva GF , Aksinenko AY , Sokolov VB , Serebryakova OG , Richardson RJ
Ref : Bioorganic & Medicinal Chemistry Lett , 19 :5528 , 2009
PubMedID: 19717305

Title : Diethyl [2,2,2-trifluoro-1-phenyl-sulfonyl-amino-1-(trifluoro-meth-yl)eth-yl]phospho-nate - Wijeyesakere_2008_Acta.Crystallogr.Sect.E.Struct.Rep.Online_64_o1425
Author(s) : Wijeyesakere SJ , Nasser FA , Kampf JW , Aksinenko AY , Sokolov VB , Malygin VV , Makhaeva GF , Richardson RJ
Ref : Acta Crystallographica Sect E Struct Rep Online , 64 :o1425 , 2008
PubMedID: 19079747

Title : Biosensor assay of neuropathy target esterase in whole blood as a new approach to OPIDN risk assessment: review of progress - Makhaeva_2007_Hum.Exp.Toxicol_26_273
Author(s) : Makhaeva GF , Malygin VV , Strakhova NN , Sigolaeva LV , Sokolovskaya LG , Eremenko AV , Kurochkin IN , Richardson RJ
Ref : Hum Exp Toxicol , 26 :273 , 2007
PubMedID: 17615108

Title : Mechanism of aging of mipafox-inhibited butyrylcholinesterase - Kropp_2007_Chem.Res.Toxicol_20_504
Author(s) : Kropp TJ , Richardson RJ
Ref : Chemical Research in Toxicology , 20 :504 , 2007
PubMedID: 17323978

Title : Aging of mipafox-inhibited human acetylcholinesterase proceeds by displacement of both isopropylamine groups to yield a phosphate adduct - Kropp_2006_Chem.Res.Toxicol_19_334
Author(s) : Kropp TJ , Richardson RJ
Ref : Chemical Research in Toxicology , 19 :334 , 2006
PubMedID: 16485911

Title : Fluorinated alpha-aminophosphonates--a new type of irreversible inhibitors of serine hydrolases -
Author(s) : Makhaeva GF , Malygin VV , Aksinenko AY , Sokolov VB , Strakhova NN , Rasdolsky AN , Richardson RJ , Martynov IV
Ref : Dokl Biochem Biophys , 400 :92 , 2005
PubMedID: 15846994

Title : Improved electrochemical analysis of neuropathy target esterase activity by a tyrosinase carbon paste electrode modified by 1-methoxyphenazine methosulfate - Sokolovskaya_2005_Biotechnol.Lett_27_1211
Author(s) : Sokolovskaya LG , Sigolaeva LV , Eremenko AV , Gachok IV , Makhaeva GF , Strakhova NN , Malygin VV , Richardson RJ , Kurochkin IN
Ref : Biotechnol Lett , 27 :1211 , 2005
PubMedID: 16158266

Title : The mipafox-inhibited catalytic domain of human neuropathy target esterase ages by reversible proton loss - Kropp_2004_Biochemistry_43_3716
Author(s) : Kropp TJ , Glynn P , Richardson RJ
Ref : Biochemistry , 43 :3716 , 2004
PubMedID: 15035642

Title : The effects of occupational exposure to chlorpyrifos on the neurologic examination of central nervous system function: a prospective cohort study - Albers_2004_J.Occup.Environ.Med_46_367
Author(s) : Albers JW , Berent S , Garabrant DH , Giordani B , Schweitzer SJ , Garrison RP , Richardson RJ
Ref : J Occup Environ Med , 46 :367 , 2004
PubMedID: 15076655

Title : Absence of sensory neuropathy among workers with occupational exposure to chlorpyrifos - Albers_2004_Muscle.Nerve_29_677
Author(s) : Albers JW , Garabrant DH , Schweitzer S , Garrison RP , Richardson RJ , Berent S
Ref : Muscle & Nerve , 29 :677 , 2004
PubMedID: 15116371

Title : The effects of occupational exposure to chlorpyrifos on the peripheral nervous system: a prospective cohort study - Albers_2004_Occup.Environ.Med_61_201
Author(s) : Albers JW , Garabrant DH , Schweitzer SJ , Garrison RP , Richardson RJ , Berent S
Ref : Occup Environ Med , 61 :201 , 2004
PubMedID: 14985514

Title : Stereoselective inactivation of Torpedo californica acetylcholinesterase by isomalathion: inhibitory reactions with (1R)- and (1S)-isomers proceed by different mechanisms - Doorn_2003_Chem.Res.Toxicol_16_958
Author(s) : Doorn JA , Thompson CM , Christner RB , Richardson RJ
Ref : Chemical Research in Toxicology , 16 :958 , 2003
PubMedID: 12924923

Title : Biosensor detection of neuropathy target esterase in whole blood as a biomarker of exposure to neuropathic organophosphorus compounds - Makhaeva_2003_J.Toxicol.Environ.Health.A_66_599
Author(s) : Makhaeva GF , Sigolaeva LV , Zhuravleva LV , Eremenko AV , Kurochkin IN , Malygin VV , Richardson RJ
Ref : J Toxicol Environ Health A , 66 :599 , 2003
PubMedID: 12746135

Title : Relative inhibitory potencies of chlorpyrifos oxon, chlorpyrifos methyl oxon, and mipafox for acetylcholinesterase versus neuropathy target esterase - Kropp_2003_J.Toxicol.Environ.Health.A_66_1145
Author(s) : Kropp TJ , Richardson RJ
Ref : J Toxicol Environ Health A , 66 :1145 , 2003
PubMedID: 12791540

Title : Quantitative structure-activity relationships predict the delayed neurotoxicity potential of a series of O-alkyl-O-methylchloroformimino phenylphosphonates - Malygin_2003_J.Toxicol.Environ.Health.A_66_611
Author(s) : Malygin VV , Sokolov VB , Richardson RJ , Makhaeva GF
Ref : J Toxicol Environ Health A , 66 :611 , 2003
PubMedID: 12746136

Title : Probing the active sites of butyrylcholinesterase and cholesterol esterase with isomalathion: conserved stereoselective inactivation of serine hydrolases structurally related to acetylcholinesterase - Doorn_2001_Chem.Res.Toxicol_14_807
Author(s) : Doorn JA , Talley TT , Thompson CM , Richardson RJ
Ref : Chemical Research in Toxicology , 14 :807 , 2001
PubMedID: 11453726

Title : Identification of Butyrylcholinesterase Adducts after Inhibition with Isomalathion Using Mass Spectrometry: Difference in Mechanism between (1R)- and (1S)-Stereoisomers - Doorn_2001_Toxicol.Appl.Pharmacol_176_73
Author(s) : Doorn JA , Schall M , Gage DA , Talley TT , Thompson CM , Richardson RJ
Ref : Toxicol Appl Pharmacol , 176 :73 , 2001
PubMedID: 11601883

Title : Inhibition of acetylcholinesterase by (1S,3S)-isomalathion proceeds with loss of thiomethyl: kinetic and mass spectral evidence for an unexpected primary leaving group - Doorn_2000_Chem.Res.Toxicol_13_1313
Author(s) : Doorn JA , Gage DA , Schall M , Talley TT , Thompson CM , Richardson RJ
Ref : Chemical Research in Toxicology , 13 :1313 , 2000
PubMedID: 11123973

Title : Kinetic Evidence for Different Mechanisms of Acetylcholinesterase Inhibition by (1R)- and (1S)-Stereoisomers of Isomalathion - Jianmongkol_1999_Toxicol.Appl.Pharmacol_155_43
Author(s) : Jianmongkol S , Marable BR , Berkman CE , Talley TT , Thompson CM , Richardson RJ
Ref : Toxicol Appl Pharmacol , 155 :43 , 1999
PubMedID: 10036217

Title : Brainstem axolemmal protein phosphorylation in vitro in hens dosed with di-1-butyl-2,2-dichlorovinyl phosphate - Huggins_1999_J.Toxicol.Environ.Health.A_56_263
Author(s) : Huggins DJ , Richardson RJ
Ref : J Toxicol Environ Health A , 56 :263 , 1999
PubMedID: 10706244

Title : Common mechanism of toxicity: a case study of organophosphorus pesticides - Mileson_1998_Toxicol.Sci_41_8
Author(s) : Mileson BE , Chambers JE , Chen WL , Dettbarn W , Ehrich M , Eldefrawi AT , Gaylor DW , Hamernik K , Hodgson E , Karczmar AG , Padilla S , Pope CN , Richardson RJ , Saunders DR , Sheets LP , Sultatos LG , Wallace KB
Ref : Toxicol Sci , 41 :8 , 1998
PubMedID: 9520337

Title : Isomalathion Stereoisomers -
Author(s) : Talley TT , Jianmongkol S , Richardson RJ , Radic Z , Thompson CM
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :531 , 1998
PubMedID:

Title : Potentiation of organophosphorus compound-induced delayed neurotoxicity (OPIDN) in the central and peripheral nervous system of the adult hen: distribution of axonal lesions - Randall_1997_J.Toxicol.Environ.Health_51_571
Author(s) : Randall JC , Yano BL , Richardson RJ
Ref : J Toxicol Environ Health , 51 :571 , 1997
PubMedID: 9242229

Title : Inhibition of neurotoxic esterase in vitro by novel carbamates - Randall_1997_Toxicol.Appl.Pharmacol_143_173
Author(s) : Randall JC , Ambroso JL , Groutas WC , Brubaker MJ , Richardson RJ
Ref : Toxicology & Applied Pharmacology , 143 :173 , 1997
PubMedID: 9073605

Title : Relative potencies of the four stereoisomers of isomalathion for inhibition of hen brain acetylcholinesterase and neurotoxic esterase in vitro - Jianmongkol_1996_Toxicol.Appl.Pharmacol_139_342
Author(s) : Jianmongkol S , Berkman CE , Thompson CM , Richardson RJ
Ref : Toxicology & Applied Pharmacology , 139 :342 , 1996
PubMedID: 8806851

Title : Assessment of the neurotoxic potential of chlorpyrifos relative to other organophosphorus compounds: a critical review of the literature. - Richardson_1995_J.Toxicol.Env.Health_44_135
Author(s) : Richardson RJ
Ref : Journal of Toxicology & Environmental Health , 44 :135 , 1995
PubMedID: 7531775

Title : Chlorpyrifos: assessment of potential for delayed neurotoxicity by repeated dosing in adult hens with monitoring of brain acetylcholinesterase, brain and lymphocyte neurotoxic esterase, and plasma butyrylcholinesterase activities - Richardson_1993_Fundam.Appl.Toxicol_21_89
Author(s) : Richardson RJ , Moore TB , Kayyali US , Randall JC
Ref : Fundamental & Applied Toxicology , 21 :89 , 1993
PubMedID: 7689993

Title : Inhibition of hen brain acetylcholinesterase and neurotoxic esterase by chlorpyrifos in vivo and kinetics of inhibition by chlorpyrifos oxon in vitro: application to assessment of neuropathic risk - Richardson_1993_Fundam.Appl.Toxicol_20_273
Author(s) : Richardson RJ , Moore TB , Kayyali US , Fowke JH , Randall JC
Ref : Fundamental & Applied Toxicology , 20 :273 , 1993
PubMedID: 7684990

Title : Phenylmethanesulfonyl fluoride elicits and intensifies the clinical expression of neuropathic insults - Moretto_1992_Arch.Toxicol_66_67
Author(s) : Moretto A , Bertolazzi M , Capodicasa E , Peraica M , Richardson RJ , Scapellato ML , Lotti M
Ref : Archives of Toxicology , 66 :67 , 1992
PubMedID: 1316117

Title : Time course of electrophysiologic effects induced by di-n-butyl-2,2-dichlorovinyl phosphate (DBCV) in the adult hen - Robertson_1988_J.Toxicol.Environ.Health_23_283
Author(s) : Robertson DG , Mattson AM , Bestervelt LL , Richardson RJ , Anderson RJ
Ref : J Toxicol Environ Health , 23 :283 , 1988
PubMedID: 3351976

Title : Kinetics of heat inactivation of phenyl valerate hydrolases from hen and rat brain - Reiner_1987_Biochem.Pharmacol_36_3181
Author(s) : Reiner E , Davis CS , Schwab BW , Schopfer LM , Richardson RJ
Ref : Biochemical Pharmacology , 36 :3181 , 1987
PubMedID: 3663234

Title : Lymphocyte and brain neurotoxic esterase: dose and time dependence of inhibition in the hen examined with three organophosphorus esters - Schwab_1986_Toxicol.Appl.Pharmacol_83_1
Author(s) : Schwab BW , Richardson RJ
Ref : Toxicol Appl Pharmacol , 83 :1 , 1986
PubMedID: 3952739

Title : Direct comparison of the distribution of neurotoxic esterase and acetylcholinesterase in rat and hen brain -
Author(s) : Hollingsworth PJ , Dudek BR , Smith CB , Richardson RJ
Ref : In: Cholinesterases, fundamental and applied aspects : proceedings of the Second International Meeting on Cholinesterases , (Brzin M, Barnard EA, Sket D, Eds) De Gruyter :483 , 1984
PubMedID:

Title : Occupational exposure to the cotton defoliants DEF and merphos. A rational approach to monitoring organophosphorous-induced delayed neurotoxicity -
Author(s) : Lotti M , Becker CE , Aminoff MJ , Woodrow JE , Seiber JN , Talcott RE , Richardson RJ
Ref : Journal of Occupational Medicine , 25 :517 , 1983
PubMedID: 6886854