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Inhibitor Report for: 2-Bromopalmitate

General
Type Fatty acid, Hexadecanoate
Chemical_Nomenclature (2R)-2-bromohexadecanoic acid
Canonical SMILES CCCCCCCCCCCCCCC(C(=O)O)Br
InChI InChI=1S/C16H31BrO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15(17)16(18)19/h15H,2-14H2,1H3,(H,18,19)/t15-/m1/s1
InChIKey DPRAYRYQQAXQPE-OAHLLOKOSA-N
Other name(s) (R)-2-Bromohexadecanoic acid ; (2R)-2-bromohexadecanoic acid ; SCHEMBL3954525 ; ZINC14278029 ; UNII-7EI4G5X28Z ; J1W
________________________________________________________________________________________________
MW|335.32
Formula|C16H31BrO2
CAS_number|
PubChem|11056766
UniChem|DPRAYRYQQAXQPE-OAHLLOKOSA-N
IUPHAR|
Wikipedia|

Target
Families | 2-Bromopalmitate ligand of proteins in family: LYsophospholipase_carboxylesterase
Stucture | 1 structure: 6QGN: Crystal structure of human acyl protein thioesterase APT1 bound to 2-Bromopalmitate
Protein | human-LYPLA1

References:
Search PubMed for references concerning: 2-Bromopalmitate
    Title: Palmitoylated acyl protein thioesterase APT2 deforms membranes to extract substrate acyl chains
    Abrami L, Audagnotto M, Ho S, Marcaida MJ, Mesquita FS, Anwar MU, Sandoz PA, Fonti G, Pojer F and van der Goot FG <1 more author(s)>
    Ref: Nat Chemical Biology, 17:438, 2021 : PubMed

            

    Title: 2-Bromopalmitate reduces protein deacylation by inhibition of acyl-protein thioesterase enzymatic activities
    Pedro MP, Vilcaes AA, Tomatis VM, Oliveira RG, Gomez GA, Daniotti JL
    Ref: PLoS ONE, 8:e75232, 2013 : PubMed