Inhibitor

Bibliography

Biblio print

Tree Display

AceDB Schema

XML Display

Feedback

Inhibitor Report for: Methyldifazine

General
Type Phenothiazine, Sulfur Compound
Chemical_Nomenclature 2-(diethylamino)-1-phenothiazin-10-ylpropan-1-one
Canonical SMILES CCN(CC)C(C)C(=O)N1C2=CC=CC=C2SC3=CC=CC=C31
InChI InChI=1S/C19H22N2OS/c1-4-20(5-2)14(3)19(22)21-15-10-6-8-12-17(15)23-18-13-9-7-11-16(18)21/h6-14H,4-5H2,1-3H3
InChIKey QCEWCMMSOWEHFC-UHFFFAOYSA-N
Other name(s) AS-1397 ; Methyldifazine ; 10-(2-(Diethylamino)propionyl)phenothiazine ; 10-(alpha-Diethylaminopropionyl)-phenothiazine hydrochloride ; Lopac0_000351 ; CHEMBL376514 ; SCHEMBL1320997
________________________________________________________________________________________________
MW|326.5
Formula|C19H22N2OS
CAS_number|
PubChem|1403
UniChem|QCEWCMMSOWEHFC-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target

References:
Search PubMed for references concerning: Methyldifazine
    Title: Novel heterobivalent tacrine derivatives as cholinesterase inhibitors with notable selectivity toward butyrylcholinesterase
    Elsinghorst PW, Tanarro CM, Gutschow M
    Ref: Journal of Medicinal Chemistry, 49:7540, 2006 : PubMed

            

    Title: In vitro human plasma leucine(5)-enkephalin degradation is inhibited by a select number of drugs with the phenothiazine molecule in their chemical structure
    Mosnaim AD, Puente J, Saavedra R, Diamond S, Wolf ME
    Ref: Pharmacology, 67:6, 2003 : PubMed