| Title : Contilisant-Belinostat Hybrids: Polyfunctionalized Indole Derivatives as Multineurotarget Drugs for the Potential Treatment of Alzheimer's Disease - Schaker-Hubner_2025_ACS.Pharmacol.Transl.Sci_8_831 |
| Author(s) : Schaker-Hubner L , Toledano-Pinedo M , Eimermacher S , Krasniqi V , Porro-Perez A , Tan K , Horn G , Stegen P , Elsinghorst PW , Wille T , Pietsch M , Gutschow M , Marco-Contelles J , Hansen FK |
| Ref : ACS Pharmacol Transl Sci , 8 :831 , 2025 |
| Abstract : |
| PubMedSearch : Schaker-Hubner_2025_ACS.Pharmacol.Transl.Sci_8_831 |
| PubMedID: 40109740 |
| Title : Aminoalkoxy-substituted coumarins: Synthesis and evaluation for reactivation of inhibited human acetylcholinesterase - Elsinghorst_2022_Arch.Pharm.(Weinheim)__e2200208 |
| Author(s) : Elsinghorst PW , Wille T , Baric D , Mertens MD , Baumann M , Kuppers J , Gutschow M |
| Ref : Arch Pharm (Weinheim) , :e2200208 , 2022 |
| Abstract : |
| PubMedSearch : Elsinghorst_2022_Arch.Pharm.(Weinheim)__e2200208 |
| PubMedID: 35876340 |
| Title : The Chemotype of Chromanones as a Privileged Scaffold for Multineurotarget Anti-Alzheimer Agents - Keuler_2022_ACS.Pharmacol.Transl.Sci_5_1097 |
| Author(s) : Keuler T , Lemke C , Elsinghorst PW , Iriepa I , Chioua M , Martinez-Grau MA , Beadle CD , Vetman T , Lopez-Munoz F , Wille T , Bartz U , Deuther-Conrad W , Marco-Contelles J , Gutschow M |
| Ref : ACS Pharmacol Transl Sci , 5 :1097 , 2022 |
| Abstract : |
| PubMedSearch : Keuler_2022_ACS.Pharmacol.Transl.Sci_5_1097 |
| PubMedID: 36407962 |
| Title : Chromenones as Multineurotargeting Inhibitors of Human Enzymes - Lemke_2019_ACS.Omega_4_22161 |
| Author(s) : Lemke C , Christmann J , Yin J , Alonso JM , Serrano E , Chioua M , Ismaili L , Martinez-Grau MA , Beadle CD , Vetman T , Dato FM , Bartz U , Elsinghorst PW , Pietsch M , Muller CE , Iriepa I , Wille T , Marco-Contelles J , Gutschow M |
| Ref : ACS Omega , 4 :22161 , 2019 |
| Abstract : |
| PubMedSearch : Lemke_2019_ACS.Omega_4_22161 |
| PubMedID: 31891098 |
| Title : Bioanalytical verification of V-type nerve agent exposure: simultaneous detection of phosphonylated tyrosines and cysteine-containing disulfide-adducts derived from human albumin - Kranawetvogl_2018_Anal.Bioanal.Chem_410_1463 |
| Author(s) : Kranawetvogl A , Kuppers J , Siegert M , Gutschow M , Worek F , Thiermann H , Elsinghorst PW , John H |
| Ref : Anal Bioanal Chem , 410 :1463 , 2018 |
| Abstract : |
| PubMedSearch : Kranawetvogl_2018_Anal.Bioanal.Chem_410_1463 |
| PubMedID: 29322229 |
| Title : A novel fluorogenic probe for the investigation of free thiols: Application to kinetic measurements of acetylcholinesterase activity - Mertens_2016_Toxicol.Lett_244_161 |
| Author(s) : Mertens MD , Bierwisch A , Li T , Gutschow M , Thiermann H , Wille T , Elsinghorst PW |
| Ref : Toxicol Lett , 244 :161 , 2016 |
| Abstract : |
| PubMedSearch : Mertens_2016_Toxicol.Lett_244_161 |
| PubMedID: 26494253 |
| Title : A hydrazide linker strategy for heterobivalent compounds as ortho- and allosteric ligands of acetylcholine-binding proteins - Elsinghorst_2011_Curr.Top.Med.Chem_11_2731 |
| Author(s) : Elsinghorst PW , Hartig W , Gundisch D , Mohr K , Trankle C , Gutschow M |
| Ref : Curr Top Med Chem , 11 :2731 , 2011 |
| Abstract : |
| PubMedSearch : Elsinghorst_2011_Curr.Top.Med.Chem_11_2731 |
| PubMedID: 22039876 |
| Title : In vivo labelling of hippocampal beta-amyloid in triple-transgenic mice with a fluorescent acetylcholinesterase inhibitor released from nanoparticles - Hartig_2010_Eur.J.Neurosci_31_99 |
| Author(s) : Hartig W , Kacza J , Paulke BR , Grosche J , Bauer U , Hoffmann A , Elsinghorst PW , Gutschow M |
| Ref : European Journal of Neuroscience , 31 :99 , 2010 |
| Abstract : |
| PubMedSearch : Hartig_2010_Eur.J.Neurosci_31_99 |
| PubMedID: 20092557 |
| Title : A gorge-spanning, high-affinity cholinesterase inhibitor to explore beta-amyloid plaques - Elsinghorst_2009_Org.Biomol.Chem_7_3940 |
| Author(s) : Elsinghorst PW , Hartig W , Goldhammer S , Grosche J , Gutschow M |
| Ref : Org Biomol Chem , 7 :3940 , 2009 |
| Abstract : |
| PubMedSearch : Elsinghorst_2009_Org.Biomol.Chem_7_3940 |
| PubMedID: 19763296 |
| Title : First gallamine-tacrine hybrid: design and characterization at cholinesterases and the M2 muscarinic receptor - Elsinghorst_2007_J.Med.Chem_50_5685 |
| Author(s) : Elsinghorst PW , Cieslik JS , Mohr K , Trankle C , Gutschow M |
| Ref : Journal of Medicinal Chemistry , 50 :5685 , 2007 |
| Abstract : |
| PubMedSearch : Elsinghorst_2007_J.Med.Chem_50_5685 |
| PubMedID: 17944454 |
| Title : Novel heterobivalent tacrine derivatives as cholinesterase inhibitors with notable selectivity toward butyrylcholinesterase - Elsinghorst_2006_J.Med.Chem_49_7540 |
| Author(s) : Elsinghorst PW , Tanarro CM , Gutschow M |
| Ref : Journal of Medicinal Chemistry , 49 :7540 , 2006 |
| Abstract : |
| PubMedSearch : Elsinghorst_2006_J.Med.Chem_49_7540 |
| PubMedID: 17149883 |