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MpPPOX

General

Type : Oxadiazolone,Oxadiazol,Lipase inhibitor,Phenoxyphenyl

Chemical_Nomenclature : 5-methoxy-3-(4-phenoxyphenyl)-1,3,4-oxadiazol-2-one

Canonical SMILES : COC1=NN(C(=O)O1)C2=CC=C(C=C2)OC3=CC=CC=C3

InChI : InChI=1S\/C15H12N2O4\/c1-19-14-16-17(15(18)21-14)11-7-9-13(10-8-11)20-12-5-3-2-4-6-12\/h2-10H,1H3

InChIKey : YAKCIFSNRAIAJM-UHFFFAOYSA-N

Other name(s) : 5-Methoxy-3-(4-phenoxyphenyl)-1,3,4-oxadiazol-2(3H)-one,CHEMBL2171700,SCHEMBL6552566,BDBM50432829

MW : 284

Formula : C15H13N2O5

CAS_number :

PubChem : 18184754

UniChem : YAKCIFSNRAIAJM-UHFFFAOYSA-N

Target

Families : MpPPOX ligand of proteins in family
Acidic_Lipase

References (1)

Title : Analysis of the discriminative inhibition of mammalian digestive lipases by 3-phenyl substituted 1,3,4-oxadiazol-2(3H)-ones. - Point_2012_Eur.J.Med.Chem_58_452
Author(s) : Point V , Pavan Kumar KV , Marc S , Delorme V , Parsiegla G , Amara S , Carriere F , Buono G , Fotiadu F , Canaan S , Leclaire J , Cavalier JF
Ref : Eur Journal of Medicinal Chemistry , 58 :452 , 2012
Abstract : Point_2012_Eur.J.Med.Chem_58_452
ESTHER : Point_2012_Eur.J.Med.Chem_58_452
PubMedSearch : Point_2012_Eur.J.Med.Chem_58_452
PubMedID: 23153815
Gene_locus related to this paper: canfa-1lipg , cavpo-2plrp , human-CEL , human-PNLIP , human-PNLIPRP2 , pig-1plip 
Array
(
    [id] => 5880
    [inhibitor] => MpPPOX
    [type] => Array
        (
            [0] => Oxadiazolone
            [1] => Oxadiazol
            [2] => Lipase inhibitor
            [3] => Phenoxyphenyl
        )

    [other_name] => Array
        (
            [0] => 5-Methoxy-3-(4-phenoxyphenyl)-1,3,4-oxadiazol-2(3H)-one
            [1] => CHEMBL2171700
            [2] => SCHEMBL6552566
            [3] => BDBM50432829
        )

    [chemical_nomenclature] => 5-methoxy-3-(4-phenoxyphenyl)-1,3,4-oxadiazol-2-one
    [formula] => C15H13N2O5
    [cas_number] => 
    [mw] => 284
    [pick_me_to_call] => display_script
    [kinetic_parameter] => MpPPOX_WT_human-PNLIPRP2 || MpPPOX_WT_pig-1plip || MpPPOX_WT_cavpo-2plrp || MpPPOX_WT_canfa-1lipg || MpPPOX_WT_human-CEL || MpPPOX_WT_human-PNLIP
    [paper] => Point_2012_Eur.J.Med.Chem_58_452
    [comment] => 
    [gene_locus] => 
    [kin_inhibitor] => 
    [cid] => 18184754
    [family] => Acidic_Lipase
    [inchikey] => YAKCIFSNRAIAJM-UHFFFAOYSA-N
    [canonicalsmiles] => COC1=NN(C(=O)O1)C2=CC=C(C=C2)OC3=CC=CC=C3
    [inchi] => InChI=1S\/C15H12N2O4\/c1-19-14-16-17(15(18)21-14)11-7-9-13(10-8-11)20-12-5-3-2-4-6-12\/h2-10H,1H3
    [wikipedia] => 
    [iupharlig] => 
    [structure] => 
    [substrate] => 
    [interact_gene_locus] => 
    [mutation] => 
    [comment2] => 
    [extoxnet] => 
    [news] => 
    [theoretical_model] => 
)