NTMGMP
a A-242 surrogate. Novichok (newcomer/ newbie/ novice, beginner/) is a series of binary chemical weapons developed by the Soviet Union and Russia between 1971 and 1993. Mirzayanov provided the first description of these agents but are somewhat different from the structures identified later.
General
Type : Organophosphate,Chemical Warfare Agent,Novichok
Chemical_Nomenclature : 1,1,3,3-tetramethyl-2-[methyl-(4-nitrophenoxy)phosphoryl]guanidine
Canonical SMILES : CN(C)C(=NP(=O)(C)OC1=CC=C(C=C1)[N+](=O)[O-])N(C)C
InChI : InChI=1S\/C12H19N4O4P\/c1-14(2)12(15(3)4)13-21(5,19)20-11-8-6-10(7-9-11)16(17)18\/h6-9H,1-5H3
InChIKey : GSFHISMWOGBZGT-UHFFFAOYSA-N
Other name(s) : 4-nitrophenyl N-(bis(dimethylamino)methylene)-P-methylphosphonamidate,A-242 surrogate,A242 surrogate
MW : 314.28
Formula : C12H19N4O4P
CAS_number :
PubChem : 163359860
UniChem : GSFHISMWOGBZGT-UHFFFAOYSA-N
IUPHAR :
Wikipedia : Novichok_agent
Target
References (3)
| Title : In vitro comparison of the acetylcholinesterase inhibition caused by V- and A-series nerve agents' surrogates - Kitagawa_2023_Chem.Biol.Interact_14ChEPon_110678 |
| Author(s) : Kitagawa DAS , Dos Santos MC , Kuca K , Franca TCC , Cavalcante SFA |
| Ref : Chemico-Biological Interactions , 383 :110678 , 2023 |
| Abstract : Kitagawa_2023_Chem.Biol.Interact_14ChEPon_110678 |
| ESTHER : Kitagawa_2023_Chem.Biol.Interact_14ChEPon_110678 |
| PubMedSearch : Kitagawa_2023_Chem.Biol.Interact_14ChEPon_110678 |
| PubMedID: 37595776 |
| Title : Unambiguous identification and determination of A234-Novichok nerve agent biomarkers in biological fluids using GC-MS\/MS and LC-MS\/MS - Mirbabaei_2022_Anal.Bioanal.Chem__ |
| Author(s) : Mirbabaei F , Mohammad-Khah A , Naseri MT , Babri M , Faraz SM , Hosseini SE , Ashrafi D |
| Ref : Anal Bioanal Chem , : , 2022 |
| Abstract : Mirbabaei_2022_Anal.Bioanal.Chem__ |
| ESTHER : Mirbabaei_2022_Anal.Bioanal.Chem__ |
| PubMedSearch : Mirbabaei_2022_Anal.Bioanal.Chem__ |
| PubMedID: 35190842 |
| Title : Are the current commercially available oximes capable of reactivating acetylcholinesterase inhibited by the nerve agents of the A-series? - Santos_2022_Arch.Toxicol__ |
| Author(s) : Santos MC , Botelho FD , Goncalves AS , Kitagawa DAS , Borges CVN , Carvalho-Silva T , Bernardo LB , Ferreira CN , Rodrigues RB , Ferreira Neto DC , Nepovimova E , Kuca K , LaPlante SR , Lima ALS , Franca TCC , Cavalcante SFA |
| Ref : Archives of Toxicology , : , 2022 |
| Abstract : Santos_2022_Arch.Toxicol__ |
| ESTHER : Santos_2022_Arch.Toxicol__ |
| PubMedSearch : Santos_2022_Arch.Toxicol__ |
| PubMedID: 35666269 |