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Prothiofos

General

Type : Insecticide,Organophosphate,Sulfur Compound

Chemical_Nomenclature : O-(2,4-Dichlorophenyl) O-ethyl S-propylphosphorodithioate

Canonical SMILES : CCCSP(=S)(OCC)OC1=C(C=C(C=C1)Cl)Cl

InChI : InChI=1S\/C11H15Cl2O2PS2\/c1-3-7-18-16(17,14-4-2)15-11-6-5-9(12)8-10(11)13\/h5-6,8H,3-4,7H2,1-2H3

InChIKey : FITIWKDOCAUBQD-UHFFFAOYSA-N

Other name(s) : Tokuthion,Prothiophos,Bideron,Dichlorpropaphos,Toyodan

MW : 345.24

Formula : C11H15Cl2O2PS2

CAS_number : 34643-46-4

PubChem : 36870

UniChem : FITIWKDOCAUBQD-UHFFFAOYSA-N

Target

Families : Prothiofos ligand of proteins in family
ACHE

References (5)

Title : Poisoning with the S-Alkyl organophosphorus insecticides profenofos and prothiofos - Eddleston_2009_QJM_102_785
Author(s) : Eddleston M , Worek F , Eyer P , Thiermann H , von Meyer L , Jeganathan K , Sheriff MH , Dawson AH , Buckley NA
Ref : Qjm , 102 :785 , 2009
Abstract : Eddleston_2009_QJM_102_785
ESTHER : Eddleston_2009_QJM_102_785
PubMedSearch : Eddleston_2009_QJM_102_785
PubMedID: 19737786

Title : Mutations of acetylcholinesterase1 contribute to prothiofos-resistance in Plutella xylostella (L.) - Lee_2007_Biochem.Biophys.Res.Commun_353_591
Author(s) : Lee DW , Choi JY , Kim WT , Je YH , Song JT , Chung BK , Boo KS , Koh YH
Ref : Biochemical & Biophysical Research Communications , 353 :591 , 2007
Abstract : Lee_2007_Biochem.Biophys.Res.Commun_353_591
ESTHER : Lee_2007_Biochem.Biophys.Res.Commun_353_591
PubMedSearch : Lee_2007_Biochem.Biophys.Res.Commun_353_591
PubMedID: 17196934
Gene_locus related to this paper: pluxy-ACHE , pluxy-ACHE1

Title : A novel function of housefly glutathione S-transferase 6B-Its effect on the retention and increase of insecticidal activity of the insecticide prothiofos - Sue_2006_J.Pestic.Sci_31_139
Author(s) : Sue M , Mikawa T , Ueda T , Nomoto Y , Miyamoto T
Ref : Journal of Pesticide Science , 31 :139 , 2006
Abstract : Sue_2006_J.Pestic.Sci_31_139
ESTHER : Sue_2006_J.Pestic.Sci_31_139
PubMedSearch : Sue_2006_J.Pestic.Sci_31_139
PubMedID:

Title : Oxidative Glutathione Conjugation and Its Novel Role in Activation of the Organophosphorus Insecticide Prothiofos - Miyamoto_2005_J.Pestic.Sci_30_31
Author(s) : Miyamoto T , Mikawa T
Ref : Journal of Pesticide Science , 30 :31 , 2005
Abstract : Miyamoto_2005_J.Pestic.Sci_30_31
ESTHER : Miyamoto_2005_J.Pestic.Sci_30_31
PubMedSearch : Miyamoto_2005_J.Pestic.Sci_30_31
PubMedID:

Title : Prothiofos metabolites in human poisoning - Sakata_1999_J.Toxicol.Clin.Toxicol_37_327
Author(s) : Sakata M , Gotoh M , Ubukata K , Hayashi H , Kotaki M , Omote T
Ref : J Toxicol Clinical Toxicology , 37 :327 , 1999
Abstract : Sakata_1999_J.Toxicol.Clin.Toxicol_37_327
ESTHER : Sakata_1999_J.Toxicol.Clin.Toxicol_37_327
PubMedSearch : Sakata_1999_J.Toxicol.Clin.Toxicol_37_327
PubMedID: 10384797 
Array
(
    [id] => 4665
    [inhibitor] => Prothiofos
    [type] => Array
        (
            [0] => Insecticide
            [1] => Organophosphate
            [2] => Sulfur Compound
        )

    [other_name] => Array
        (
            [0] => Tokuthion
            [1] => Prothiophos
            [2] => Bideron
            [3] => Dichlorpropaphos
            [4] => Toyodan
        )

    [chemical_nomenclature] => O-(2,4-Dichlorophenyl) O-ethyl S-propylphosphorodithioate
    [formula] => C11H15Cl2O2PS2
    [cas_number] => 34643-46-4
    [mw] => 345.24
    [pick_me_to_call] => display_script
    [kinetic_parameter] => 
    [paper] => Eddleston_2009_Qjm_102_785 || Lee_2007_Biochem.Biophys.Res.Commun_353_591 || Miyamoto_2005_J.Pestic.Sci_30_31 || Sakata_1999_J.Toxicol.Clin.Toxicol_37_327 || Sue_2006_J.Pestic.Sci_31_139
    [comment] => 
    [gene_locus] => 
    [kin_inhibitor] => 
    [cid] => 36870
    [family] => ACHE
    [inchikey] => FITIWKDOCAUBQD-UHFFFAOYSA-N
    [canonicalsmiles] => CCCSP(=S)(OCC)OC1=C(C=C(C=C1)Cl)Cl
    [inchi] => InChI=1S\/C11H15Cl2O2PS2\/c1-3-7-18-16(17,14-4-2)15-11-6-5-9(12)8-10(11)13\/h5-6,8H,3-4,7H2,1-2H3
    [wikipedia] => 
    [iupharlig] => 
    [structure] => 
    [substrate] => 
    [interact_gene_locus] => 
    [mutation] => 
    [comment2] => 
    [extoxnet] => 
    [news] => 
    [theoretical_model] => 
)