Eyer P

General

Full name : Eyer Peter

First name : Peter

Mail : Walther-Straub-Institute of Pharmacology and Toxicology\; Ludwig-Maximilians-University Munich\; Goethestr. 33\; D-80336 Munchen

Zip Code :

City :

Country : Germany

Email : peter.eyer@lrz.uni.muenchen.de

Phone : +4989218075722

Fax :

Website : \/\/www.wsi.med.uni-muenchen.de\/das_institut\/geschichte\/eyer\/index.html

Directory :

References (84)

Title : Determination of acetylcholinesterase activity by the Ellman assay: a versatile tool for in vitro research on medical countermeasures against organophosphate poisoning - Worek_2012_Drug.Test.Anal_4_282
Author(s) : Worek F , Eyer P , Thiermann H
Ref : Drug Test Anal , 4 :282 , 2012
PubMedID: 21998030

Title : Kinetic analysis of interactions of paraoxon and oximes with human, Rhesus monkey, swine, rabbit, rat and guinea pig acetylcholinesterase - Worek_2011_Toxicol.Lett_200_19
Author(s) : Worek F , Aurbek N , Wille T , Eyer P , Thiermann H
Ref : Toxicol Lett , 200 :19 , 2011
PubMedID: 20971170

Title : Kinetic prerequisites of oximes as effective reactivators of organophosphate-inhibited acetylcholinesterase: a theoretical approach - Worek_2011_J.Enzyme.Inhib.Med.Chem_26_303
Author(s) : Worek F , Aurbek N , Wille T , Eyer P , Thiermann H
Ref : J Enzyme Inhib Med Chem , 26 :303 , 2011
PubMedID: 20807085

Title : Atropine maintenance dosage in patients with severe organophosphate pesticide poisoning - Thiermann_2011_Toxicol.Lett_206_77
Author(s) : Thiermann H , Steinritz D , Worek F , Radtke M , Eyer P , Eyer F , Felgenhauer N , Zilker T
Ref : Toxicol Lett , 206 :77 , 2011
PubMedID: 21771644

Title : Obituary: In memory of Elsa Reiner - Eyer_2011_Toxicol.Lett_206_1
Author(s) : Eyer P , Szinicz L
Ref : Toxicol Lett , 206 :1 , 2011
PubMedID:

Title : Evaluation of the Test-mate ChE (cholinesterase) field kit in acute organophosphorus poisoning - Rajapakse_2011_Ann.Emerg.Med_58_559
Author(s) : Rajapakse BN , Thiermann H , Eyer P , Worek F , Bowe SJ , Dawson AH , Buckley NA
Ref : Annals of Emergency Medicine , 58 :559 , 2011
PubMedID: 22098995

Title : Evaluation of medical countermeasures against organophosphorus compounds: the value of experimental data and computer simulations - Worek_2010_Chem.Biol.Interact_187_259
Author(s) : Worek F , Aurbek N , Herkert NM , John H , Eddleston M , Eyer P , Thiermann H
Ref : Chemico-Biological Interactions , 187 :259 , 2010
PubMedID: 19917271

Title : Reactivation of organophosphate-inhibited human, Cynomolgus monkey, swine and guinea pig acetylcholinesterase by MMB-4: a modified kinetic approach - Worek_2010_Toxicol.Appl.Pharmacol_249_231
Author(s) : Worek F , Wille T , Aurbek N , Eyer P , Thiermann H
Ref : Toxicol Appl Pharmacol , 249 :231 , 2010
PubMedID: 20888357

Title : Paradox findings may challenge orthodox reasoning in acute organophosphate poisoning - Eyer_2010_Chem.Biol.Interact_187_270
Author(s) : Eyer P , Worek F , Thiermann H , Eddleston M
Ref : Chemico-Biological Interactions , 187 :270 , 2010
PubMedID: 19883634

Title : Comparative study of oxime-induced reactivation of erythrocyte and muscle AChE from different animal species following inhibition by sarin or paraoxon - Herkert_2010_Toxicol.Lett_194_94
Author(s) : Herkert NM , Aurbek N , Eyer P , Thiermann H , Worek F
Ref : Toxicol Lett , 194 :94 , 2010
PubMedID: 20156534

Title : Pharmacokinetics of obidoxime in patients poisoned with organophosphorus compounds - Thiermann_2010_Toxicol.Lett_197_236
Author(s) : Thiermann H , Eyer F , Felgenhauer N , Pfab R , Zilker T , Eyer P , Worek F
Ref : Toxicol Lett , 197 :236 , 2010
PubMedID: 20542100

Title : Hypothermia and Fever after organophosphorus poisoning in humans--a prospective case series - Moffatt_2010_J.Med.Toxicol_6_379
Author(s) : Moffatt A , Mohammed F , Eddleston M , Azher S , Eyer P , Buckley NA
Ref : J Med Toxicol , 6 :379 , 2010
PubMedID: 20300985

Title : Muscle force and acetylcholinesterase activity in mouse hemidiaphragms exposed to paraoxon and treated by oximes in vitro - Thiermann_2010_Toxicology_272_46
Author(s) : Thiermann H , Eyer P , Worek F
Ref : Toxicology , 272 :46 , 2010
PubMedID: 20385200

Title : Monitoring of neuromuscular transmission in organophosphate pesticide-poisoned patients - Thiermann_2009_Toxicol.Lett_191_297
Author(s) : Thiermann H , Zilker T , Eyer F , Felgenhauer N , Eyer P , Worek F
Ref : Toxicol Lett , 191 :297 , 2009
PubMedID: 19793545

Title : Poisoning with the S-Alkyl organophosphorus insecticides profenofos and prothiofos - Eddleston_2009_QJM_102_785
Author(s) : Eddleston M , Worek F , Eyer P , Thiermann H , von Meyer L , Jeganathan K , Sheriff MH , Dawson AH , Buckley NA
Ref : Qjm , 102 :785 , 2009
PubMedID: 19737786

Title : Suitability of human butyrylcholinesterase as therapeutic marker and pseudo catalytic scavenger in organophosphate poisoning: a kinetic analysis - Aurbek_2009_Toxicology_259_133
Author(s) : Aurbek N , Thiermann H , Eyer F , Eyer P , Worek F
Ref : Toxicology , 259 :133 , 2009
PubMedID: 19428953

Title : Comments on Efficacy of two new asymmetric bispyridinium oximes (K-27 and K-48) in rats exposed to diisopropylfluorophosphate: comparison with pralidoxime, obidoxime, trimedoxime, methoxime, and HI 6 -
Author(s) : Theirmann H , Worek F , Eyer P
Ref : Toxicol Mech Methods , 19 :334\; author reply 335 , 2009
PubMedID: 19778225

Title : Obidoxime in acute organophosphate poisoning: 1 - clinical effectiveness - Eyer_2009_Clin.Toxicol.(Phila)_47_798
Author(s) : Eyer F , Worek F , Eyer P , Felgenhauer N , Haberkorn M , Zilker T , Thiermann H
Ref : Clinical Toxicology (Phila) , 47 :798 , 2009
PubMedID: 19778163

Title : Relationship between blood alcohol concentration on admission and outcome in dimethoate organophosphorus self-poisoning - Eddleston_2009_Br.J.Clin.Pharmacol_68_916
Author(s) : Eddleston M , Gunnell D , von Meyer L , Eyer P
Ref : British Journal of Clinical Pharmacology , 68 :916 , 2009
PubMedID: 20002086

Title : Extreme variability in the formation of chlorpyrifos oxon (CPO) in patients poisoned by chlorpyrifos (CPF) - Eyer_2009_Biochem.Pharmacol_78_531
Author(s) : Eyer F , Roberts DM , Buckley NA , Eddleston M , Thiermann H , Worek F , Eyer P
Ref : Biochemical Pharmacology , 78 :531 , 2009
PubMedID: 19433070

Title : Pralidoxime in acute organophosphorus insecticide poisoning--a randomised controlled trial - Eddleston_2009_PLoS.Med_6_e1000104
Author(s) : Eddleston M , Eyer P , Worek F , Juszczak E , Alder N , Mohamed F , Senarathna L , Hittarage A , Azher S , Jeganathan K , Jayamanne S , von Meyer L , Dawson AH , Sheriff MH , Buckley NA
Ref : PLoS Med , 6 :e1000104 , 2009
PubMedID: 19564902

Title : Obidoxime in acute organophosphate poisoning: 2 - PK\/PD relationships - Thiermann_2009_Clin.Toxicol.(Phila)_47_807
Author(s) : Thiermann H , Worek F , Eyer P , Eyer F , Felgenhauer N , Zilker T
Ref : Clinical Toxicology (Phila) , 47 :807 , 2009
PubMedID: 19778190

Title : Clinical outcomes and kinetics of propanil following acute self-poisoning: a prospective case series - Roberts_2009_BMC.Clin.Pharmacol_9_3
Author(s) : Roberts DM , Heilmair R , Buckley NA , Dawson AH , Fahim M , Eddleston M , Eyer P
Ref : BMC Clin Pharmacol , 9 :3 , 2009
PubMedID: 19220887

Title : Hypotension in severe dimethoate self-poisoning - Davies_2008_Clin.Toxicol.(Phila)_46_880
Author(s) : Davies J , Roberts D , Eyer P , Buckley N , Eddleston M
Ref : Clinical Toxicology (Phila) , 46 :880 , 2008
PubMedID: 19003596

Title : Comparison of the oxime-induced reactivation of erythrocyte and muscle acetylcholinesterase following inhibition by sarin or paraoxon, using a perfusion model for the real-time determination of membrane-bound acetylcholinesterase activity - Eckert_2008_Biochem.Pharmacol_75_698
Author(s) : Eckert S , Eyer P , Herkert N , Bumm R , Weber G , Thiermann H , Worek F
Ref : Biochemical Pharmacology , 75 :698 , 2008
PubMedID: 17977518

Title : Effects of oximes on rate of decarbamylation of human red blood cell AChE measured with two different methods - Eckert_2008_Biochem.Pharmacol_75_1561
Author(s) : Eckert S , Eyer P , Melzer M , Thiermann H , Worek F
Ref : Biochemical Pharmacology , 75 :1561 , 2008
PubMedID: 18281016

Title : Management of acute organophosphorus pesticide poisoning - Eddleston_2008_Lancet_371_597
Author(s) : Eddleston M , Buckley NA , Eyer P , Dawson AH
Ref : Lancet , 371 :597 , 2008
PubMedID: 17706760

Title : Predicting outcome using butyrylcholinesterase activity in organophosphorus pesticide self-poisoning - Eddleston_2008_QJM_101_467
Author(s) : Eddleston M , Eyer P , Worek F , Sheriff MH , Buckley NA
Ref : Qjm , 101 :467 , 2008
PubMedID: 18375477

Title : Are we using the right dose? - a tale of mole and gram -
Author(s) : Eyer P , Eddleston M , Thiermann H , Worek F , Buckley NA
Ref : British Journal of Clinical Pharmacology , 66 :451 , 2008
PubMedID: 18662291

Title : Reactions of isodimethoate with human red cell acetylcholinesterase - Eyer_2008_Biochem.Pharmacol_75_2045
Author(s) : Eyer P , Radtke M , Worek F
Ref : Biochemical Pharmacology , 75 :2045 , 2008
PubMedID: 18384757

Title : Enzyme-based assay for quantification of chlorpyrifos oxon in human plasma - Heilmair_2008_Toxicol.Lett_181_19
Author(s) : Heilmair R , Eyer F , Eyer P
Ref : Toxicol Lett , 181 :19 , 2008
PubMedID: 18655824

Title : Identical kinetics of human erythrocyte and muscle acetylcholinesterase with respect to carbamate pre-treatment, residual activity upon soman challenge and spontaneous reactivation after withdrawal of the inhibitors - Herkert_2008_Toxicology_246_188
Author(s) : Herkert NM , Eckert S , Eyer P , Bumm R , Weber G , Thiermann H , Worek F
Ref : Toxicology , 246 :188 , 2008
PubMedID: 18304715

Title : Red blood cell acetylcholinesterase and plasma butyrylcholinesterase status: important indicators for the treatment of patients poisoned by organophosphorus compounds - Thiermann_2007_Arh.Hig.Rada.Toksikol_58_359
Author(s) : Thiermann H , Kehe K , Steinritz D , Mikler J , Hill I , Zilker T , Eyer P , Worek F
Ref : Arh Hig Rada Toksikol , 58 :359 , 2007
PubMedID: 17913691

Title : Lessons to be learnt from organophosphorus pesticide poisoning for the treatment of nerve agent poisoning - Thiermann_2007_Toxicology_233_145
Author(s) : Thiermann H , Szinicz L , Eyer P , Felgenhauer N , Zilker T , Worek F
Ref : Toxicology , 233 :145 , 2007
PubMedID: 17161895

Title : Recent advances in evaluation of oxime efficacy in nerve agent poisoning by in vitro analysis - Worek_2007_Toxicol.Appl.Pharmacol_219_226
Author(s) : Worek F , Eyer P , Aurbek N , Szinicz L , Thiermann H
Ref : Toxicol Appl Pharmacol , 219 :226 , 2007
PubMedID: 17112559

Title : Simulation of cholinesterase status at different scenarios of nerve agent exposure - Worek_2007_Toxicology_233_155
Author(s) : Worek F , Eyer P , Szinicz L , Thiermann H
Ref : Toxicology , 233 :155 , 2007
PubMedID: 16904807

Title : Reversible inhibition of acetylcholinesterase by carbamates or huperzine A increases residual activity of the enzyme upon soman challenge - Eckert_2007_Toxicology_233_180
Author(s) : Eckert S , Eyer P , Worek F
Ref : Toxicology , 233 :180 , 2007
PubMedID: 17097792

Title : Kinetic analysis of reactivation and aging of human acetylcholinesterase inhibited by different phosphoramidates - Worek_2007_Biochem.Pharmacol_73_1807
Author(s) : Worek F , Aurbek N , Koller M , Becker C , Eyer P , Thiermann H
Ref : Biochemical Pharmacology , 73 :1807 , 2007
PubMedID: 17382909

Title : In memory of Ilse Hagedorn - Eyer_2007_Toxicology_233_3
Author(s) : Eyer P
Ref : Toxicology , 233 :3 , 2007
PubMedID: 17511052

Title : Testing of antidotes for organophosphorus compounds: experimental procedures and clinical reality - Eyer_2007_Toxicology_233_108
Author(s) : Eyer P , Szinicz L , Thiermann H , Worek F , Zilker T
Ref : Toxicology , 233 :108 , 2007
PubMedID: 17010492

Title : Preparation and characterization of dialkylphosphoryl-obidoxime conjugates, potent anticholinesterase derivatives that are quickly hydrolyzed by human paraoxonase (PON1192Q) - Stenzel_2007_Biochem.Pharmacol_74_1390
Author(s) : Stenzel J , Worek F , Eyer P
Ref : Biochemical Pharmacology , 74 :1390 , 2007
PubMedID: 17714697

Title : Development of antidotes: problems and strategies - Szinicz_2007_Toxicology_233_23
Author(s) : Szinicz L , Worek F , Thiermann H , Kehe K , Eckert S , Eyer P
Ref : Toxicology , 233 :23 , 2007
PubMedID: 16949190

Title : Analysis of inhibition, reactivation and aging kinetics of highly toxic organophosphorus compounds with human and pig acetylcholinesterase - Aurbek_2006_Toxicology_224_91
Author(s) : Aurbek N , Thiermann H , Szinicz L , Eyer P , Worek F
Ref : Toxicology , 224 :91 , 2006
PubMedID: 16720069

Title : Application of kinetic-based computer modelling to evaluate the efficacy of HI 6 in percutaneous VX poisoning - Aurbek_2006_Toxicology_224_74
Author(s) : Aurbek N , Thiermann H , Szinicz L , Eyer P , Worek F
Ref : Toxicology , 224 :74 , 2006
PubMedID: 16740352

Title : Development of a dynamic model for real-time determination of membrane-bound acetylcholinesterase activity upon perfusion with inhibitors and reactivators - Eckert_2006_Biochem.Pharmacol_72_358
Author(s) : Eckert S , Eyer P , Muckter H , Worek F
Ref : Biochemical Pharmacology , 72 :358 , 2006
PubMedID: 16725113

Title : Kinetic analysis of the protection afforded by reversible inhibitors against irreversible inhibition of acetylcholinesterase by highly toxic organophosphorus compounds - Eckert_2006_Biochem.Pharmacol_72_344
Author(s) : Eckert S , Eyer P , Muckter H , Worek F
Ref : Biochemical Pharmacology , 72 :344 , 2006
PubMedID: 16780806

Title : Pralidoxime for organophosphate poisoning -
Author(s) : Eyer P , Buckley N
Ref : Lancet , 368 :2110 , 2006
PubMedID: 17174692

Title : Respiratory failure in acute organophosphorus pesticide self-poisoning - Eddleston_2006_Qjm_99_513
Author(s) : Eddleston M , Mohamed F , Davies JO , Eyer P , Worek F , Sheriff MH , Buckley NA
Ref : Qjm , 99 :513 , 2006
PubMedID: 16861715

Title : The liberation of thiocholine from acetylthiocholine (ASCh) by pralidoxime iodide (2=PAM) and other oximes (obidoxime and diacetylmonoxime) -
Author(s) : Worek F , Eyer P
Ref : Toxicol Lett , 167 :256 , 2006
PubMedID: 17113251

Title : Effects of oximes on muscle force and acetylcholinesterase activity in isolated mouse hemidiaphragms exposed to paraoxon - Thiermann_2005_Toxicology_214_190
Author(s) : Thiermann H , Eyer P , Worek F , Szinicz L
Ref : Toxicology , 214 :190 , 2005
PubMedID: 16040183

Title : Correlation between red blood cell acetylcholinesterase activity and neuromuscular transmission in organophosphate poisoning - Thiermann_2005_Chem.Biol.Interact_157-158_345
Author(s) : Thiermann H , Szinicz L , Eyer P , Zilker T , Worek F
Ref : Chemico-Biological Interactions , 157-158 :345 , 2005
PubMedID: 16263103

Title : Evaluation of oxime efficacy in nerve agent poisoning: development of a kinetic-based dynamic model - Worek_2005_Toxicol.Appl.Pharmacol_209_193
Author(s) : Worek F , Szinicz L , Eyer P , Thiermann H
Ref : Toxicol Appl Pharmacol , 209 :193 , 2005
PubMedID: 15904945

Title : Differences between organophosphorus insecticides in human self-poisoning: a prospective cohort study - Eddleston_2005_Lancet_366_1452
Author(s) : Eddleston M , Eyer P , Worek F , Mohamed F , Senarathna L , von Meyer L , Juszczak E , Hittarage A , Azhar S , Dissanayake W , Sheriff MH , Szinicz L , Dawson AH , Buckley NA
Ref : Lancet , 366 :1452 , 2005
PubMedID: 16243090

Title : Formation and disposition of diethylphosphoryl-obidoxime, a potent anticholinesterase that is hydrolyzed by human paraoxonase (PON1) - Kiderlen_2005_Biochem.Pharmacol_69_1853
Author(s) : Kiderlen D , Eyer P , Worek F
Ref : Biochemical Pharmacology , 69 :1853 , 2005
PubMedID: 15876422

Title : Kinetic analysis of interactions between human acetylcholinesterase, structurally different organophosphorus compounds and oximes - Worek_2004_Biochem.Pharmacol_68_2237
Author(s) : Worek F , Thiermann H , Szinicz L , Eyer P
Ref : Biochemical Pharmacology , 68 :2237 , 2004
PubMedID: 15498514

Title : Molar absorption coefficients for the reduced Ellman reagent: reassessment - Eyer_2003_Anal.Biochem_312_224
Author(s) : Eyer P , Worek F , Kiderlen D , Sinko G , Stuglin A , Simeon-Rudolf V , Reiner E
Ref : Analytical Biochemistry , 312 :224 , 2003
PubMedID: 12531209

Title : Human parathion poisoning. A toxicokinetic analysis - Eyer_2003_Toxicol.Rev_22_143
Author(s) : Eyer F , Meischner V , Kiderlen D , Thiermann H , Worek F , Haberkorn M , Felgenhauer N , Zilker T , Eyer P
Ref : Toxicol Rev , 22 :143 , 2003
PubMedID: 15181664

Title : The role of oximes in the management of organophosphorus pesticide poisoning - Eyer_2003_Toxicol.Rev_22_165
Author(s) : Eyer P
Ref : Toxicol Rev , 22 :165 , 2003
PubMedID: 15181665

Title : Reactivation kinetics of acetylcholinesterase from different species inhibited by highly toxic organophosphates - Worek_2002_Arch.Toxicol_76_523
Author(s) : Worek F , Reiter G , Eyer P , Szinicz L
Ref : Archives of Toxicology , 76 :523 , 2002
PubMedID: 12242610

Title : Oximes in acute organophosphorus pesticide poisoning: a systematic review of clinical trials - Eddleston_2002_QJM_95_275
Author(s) : Eddleston M , Szinicz L , Eyer P , Buckley N
Ref : Qjm , 95 :275 , 2002
PubMedID: 11978898

Title : Equipotent cholinesterase reactivation in vitro by the nerve agent antidotes HI 6 dichloride and HI 6 dimethanesulfonate - Krummer_2002_Arch.Toxicol_76_589
Author(s) : Krummer S , Thiermann H , Worek F , Eyer P
Ref : Archives of Toxicology , 76 :589 , 2002
PubMedID: 12373455

Title : Intoxication with huperzine A, a potent anticholinesterase found in the fir club moss - Felgenhauer_2000_J.Toxicol.Clin.Toxicol_38_803
Author(s) : Felgenhauer N , Zilker T , Worek F , Eyer P
Ref : J Toxicol Clinical Toxicology , 38 :803 , 2000
PubMedID: 11192470

Title : Effect of human plasma on the reactivation of sarin-inhibited human erythrocyte acetylcholinesterase - Worek_2000_Arch.Toxicol_74_21
Author(s) : Worek F , Eyer P , Kiderlen D , Thiermann H , Szinicz L
Ref : Archives of Toxicology , 74 :21 , 2000
PubMedID: 10817663

Title : The phosphoryl oxime-destroying activity of human plasma - Kiderlen_2000_Arch.Toxicol_74_27
Author(s) : Kiderlen D , Worek F , Klimmek R , Eyer P
Ref : Archives of Toxicology , 74 :27 , 2000
PubMedID: 10817664

Title : Modern strategies in therapy of organophosphate poisoning - Thiermann_1999_Toxicol.Lett_107_233
Author(s) : Thiermann H , Szinicz L , Eyer F , Worek F , Eyer P , Felgenhauer N , Zilker T
Ref : Toxicol Lett , 107 :233 , 1999
PubMedID: 10414801

Title : Dimethylphosphoryl-inhibited human cholinesterases: inhibition, reactivation, and aging kinetics - Worek_1999_Arch.Toxicol_73_7
Author(s) : Worek F , Diepold C , Eyer P
Ref : Archives of Toxicology , 73 :7 , 1999
PubMedID: 10207609

Title : Improved determination of acetylcholinesterase activity in human whole blood - Worek_1999_Clin.Chim.Acta_288_73
Author(s) : Worek F , Mast U , Kiderlen D , Diepold C , Eyer P
Ref : Clinica Chimica Acta , 288 :73 , 1999
PubMedID: 10529460

Title : Inhibition, reactivation and aging kinetics of cyclohexylmethylphosphonofluoridate-inhibited human cholinesterases - Worek_1998_Arch.Toxicol_72_580
Author(s) : Worek F , Eyer P , Szinicz L
Ref : Archives of Toxicology , 72 :580 , 1998
PubMedID: 9806430

Title : Acetylcholinesterase, a Versatile Protein -
Author(s) : Szinicz L , Thiermann H , Worek F , Eyer P
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :269 , 1998
PubMedID:

Title : Enzyme-based assay for quantification of paraoxon in blood of parathion poisoned patients - Eyer_1998_Hum.Exp.Toxicol_17_645
Author(s) : Eyer F , Eyer P
Ref : Hum Exp Toxicol , 17 :645 , 1998
PubMedID: 9988368

Title : Factors influencing the efficacy of obidoxime in organophosphate pesticides poisoning [editorial] -
Author(s) : Zilker T , Felgenhauer N , Hibler A , Pfab R , Thiermann H , Worek F , Eyer P
Ref : Przegl Lek , 54 :662 , 1997
PubMedID: 9478082

Title : Cholinesterase status, pharmacokinetics and laboratory findings during obidoxime therapy in organophosphate poisoned patients - Thiermann_1997_Hum.Exp.Toxicol_16_473
Author(s) : Thiermann H , Mast U , Klimmek R , Eyer P , Hibler A , Pfab R , Felgenhauer N , Zilker T
Ref : Hum Exp Toxicol , 16 :473 , 1997
PubMedID: 9292288

Title : Reappraisal of indications and limitations of oxime therapy in organophosphate poisoning - Worek_1997_Hum.Exp.Toxicol_16_466
Author(s) : Worek F , Backer M , Thiermann H , Szinicz L , Mast U , Klimmek R , Eyer P
Ref : Hum Exp Toxicol , 16 :466 , 1997
PubMedID: 9292287

Title : Pharmacokinetics of atropine in dogs after i.m. injection with newly developed dry\/wet combination autoinjectors containing HI 6 or HLo 7 - Thiermann_1996_Arch.Toxicol_70_293
Author(s) : Thiermann H , Radtke M , Spohrer U , Klimmek R , Eyer P
Ref : Archives of Toxicology , 70 :293 , 1996
PubMedID: 8852700

Title : HI 6 dimethanesulfonate has better dissolution properties than HI 6 dichloride for application in dry\/wet autoinjectors - Thiermann_1996_Int.J.Pharm_137_167
Author(s) : Thiermann H , Seidl S , Eyer P
Ref : Int J Pharm , 137 :167 , 1996
PubMedID:

Title : Neuropsychopathological changes by organophosphorus compounds--a review. - Eyer_1995_Human.Exp.Toxicol_14_857
Author(s) : Eyer P
Ref : Hum Exp Toxicol , 14 :857 , 1995
PubMedID: 8588945

Title : Pharmacokinetics of the oximes HI 6 and HLo 7 in dogs after i.m. injection with newly developed dry\/wet autoinjectors - Spohrer_1994_Arch.Toxicol_68_480
Author(s) : Spohrer U , Thiermann H , Klimmek R , Eyer P
Ref : Archives of Toxicology , 68 :480 , 1994
PubMedID: 7802588

Title : HLo 7 dimethanesulfonate, a potent bispyridinium-dioxime against anticholinesterases - Eyer_1992_Arch.Toxicol_66_603
Author(s) : Eyer P , Hagedorn I , Klimmek R , Lippstreu P , Loffler M , Oldiges H , Spohrer U , Steidl I , Szinicz L , Worek F
Ref : Archives of Toxicology , 66 :603 , 1992
PubMedID: 1482283

Title : Studies on the stability and decomposition of the Hagedorn-oxime HLo 7 in aqueous solution - Eyer_1989_Arch.Toxicol_63_59
Author(s) : Eyer P , Ladstetter B , Schafer W , Sonnenbichler J
Ref : Archives of Toxicology , 63 :59 , 1989
PubMedID: 2742503

Title : Study on the stability of the oxime HI 6 in aqueous solution - Eyer_1988_Arch.Toxicol_62_224
Author(s) : Eyer P , Hagedorn I , Ladstetter B
Ref : Archives of Toxicology , 62 :224 , 1988
PubMedID: 3196158

Title : Formation of cyanide after i.v. administration of the oxime HI 6 to dogs - Eyer_1987_Arch.Toxicol_61_63
Author(s) : Eyer P , Kawan A , Ladstetter B
Ref : Archives of Toxicology , 61 :63 , 1987
PubMedID: 3439876

Title : Studies on the decomposition of the oxime HI 6 in aqueous solution - Eyer_1986_Arch.Toxicol_59_266
Author(s) : Eyer P , Hell W , Kawan A , Klehr H
Ref : Archives of Toxicology , 59 :266 , 1986
PubMedID: 3827594

Title : Pharmacokinetics and pharmacodynamics of the oxime HI6 in dogs - Klimmek_1986_Arch.Toxicol_59_272
Author(s) : Klimmek R , Eyer P
Ref : Archives of Toxicology , 59 :272 , 1986
PubMedID: 3827595

Title : Pharmacokinetics and toxicity of the oxime HGG 12 in dogs - Klimmek_1985_Arch.Toxicol_57_237
Author(s) : Klimmek R , Eyer P
Ref : Archives of Toxicology , 57 :237 , 1985
PubMedID: 4091648