Gene Locus : human-BCHE
Mode of mutation : Site directed mutagenesis
Disease :
Summary : Aging F329A increases half-life of aging by DFP 2 times Masson_1997_Biochem.J_327_601 || Cationic triarylmethane dyes Biberoglu_2011_Arch.Biochem.Biophys_511_64
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification : Aging || Cationic triarylmethane dyes
Torpedo_number : 331
Kinetic Parameter : No kinetic parameter
News : No news
Comment :
p.F329A Phe329Ala (p.F357A Phe357Ala in primary sequence with 28 amino-acids signal peptide) F329A increases half-life of aging by DFP 2 times
| Title : Probing the peripheral site of human butyrylcholinesterase - Macdonald_2012_Biochemistry_51_7046 |
| Author(s) : Macdonald IR , Martin E , Rosenberry TL , Darvesh S |
| Ref : Biochemistry , 51 :7046 , 2012 |
| Abstract : |
| PubMedSearch : Macdonald_2012_Biochemistry_51_7046 |
| PubMedID: 22901043 |
| Title : The role of Phe329 in binding of cationic triarylmethane dyes to human butyrylcholinesterase - Biberoglu_2011_Arch.Biochem.Biophys_511_64 |
| Author(s) : Biberoglu K , Tacal O , Akbulut H |
| Ref : Archives of Biochemistry & Biophysics , 511 :64 , 2011 |
| Abstract : |
| PubMedSearch : Biberoglu_2011_Arch.Biochem.Biophys_511_64 |
| PubMedID: 21530486 |
| Title : Aging of di-isopropyl-phosphorylated human butyrylcholinesterase - Masson_1997_Biochem.J_327_601 |
| Author(s) : Masson P , Fortier PL , Albaret C , Froment MT , Bartels CF , Lockridge O |
| Ref : Biochemical Journal , 327 ( Pt 2) :601 , 1997 |
| Abstract : |
| PubMedSearch : Masson_1997_Biochem.J_327_601 |
| PubMedID: 9359435 |