W86Y_mouse-ACHE

General

Gene Locus : mouse-ACHE

Mode of mutation : Site directed mutagenesis

Disease :

Summary : Fasciculin inhibition allosteric control of AChE catalysis by Fasciculin Radic_1995_J.Biol.Chem_270_20391 || Choline binding site allosteric control of AChE catalysis by Fasciculin Ashani_1995_5th.ChE.Meeting.Madras__133

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification : Choline binding site || Fasciculin inhibition

Torpedo_number : 84

Kinetic Parameter : No kinetic parameter

News : No news

Comment :
p.W86Y Trp86Tyr Fasciculin inhibition\;allosteric control of AChE catalysis by Fasciculin

References (2)

Title : Amino Acid Residues that Control Mono- and Bisquaternary Oxime-Induced Reactivation of O-Ethyl Methylphosphonylated Cholinesterases -
Author(s) : Ashani Y , Radic Z , Tsigelny I , Vellom DC , Pickering NA , Quinn DM , Doctor BP , Taylor P
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :133 , 1995
PubMedID:

Title : Allosteric control of acetylcholinesterase catalysis by fasciculin - Radic_1995_J.Biol.Chem_270_20391
Author(s) : Radic Z , Quinn DM , Vellom DC , Camp S , Taylor P
Ref : Journal of Biological Chemistry , 270 :20391 , 1995
PubMedID: 7657613