Gene Locus : human-BCHE
Mode of mutation : Site directed mutagenesis
Disease :
Summary : Peripheral Anionic site interraction 70\/332 Masson_1999_Biochim.Biophys.Acta_1433_281
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification : Succinylthiocholine binding || Peripheral Anionic Site
Torpedo_number : 334
Kinetic Parameter : No kinetic parameter
News : No news
Comment :
p.Y332A Tyr332Ala (p.Y360A Tyr360Ala in primary sequence with 28 amino-acids signal peptide) Peripheral Anionic site\;interraction 70(98)\/332(360)
| Title : Probing the peripheral site of human butyrylcholinesterase - Macdonald_2012_Biochemistry_51_7046 |
| Author(s) : Macdonald IR , Martin E , Rosenberry TL , Darvesh S |
| Ref : Biochemistry , 51 :7046 , 2012 |
| Abstract : |
| PubMedSearch : Macdonald_2012_Biochemistry_51_7046 |
| PubMedID: 22901043 |
| Title : Interaction between the peripheral site residues of human butyrylcholinesterase, D70 and Y332, in binding and hydrolysis of substrates - Masson_1999_Biochim.Biophys.Acta_1433_281 |
| Author(s) : Masson P , Xie W , Froment MT , Levitsky V , Fortier PL , Albaret C , Lockridge O |
| Ref : Biochimica & Biophysica Acta , 1433 :281 , 1999 |
| Abstract : |
| PubMedSearch : Masson_1999_Biochim.Biophys.Acta_1433_281 |
| PubMedID: 10446378 |