F115S_drome-ACHE

General

Gene Locus : drome-ACHE

Mode of mutation : Natural mutant

Disease :

Summary : OP-resistance OP-resistance lower than multiple mutations,mut found in Saltillo strain together with I199V G303A F368Y Mutero_1994_Proc.Natl.Acad.Sci.U.S.A_91_5922

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification : OP-resistance

Torpedo_number : 78

Kinetic Parameter : No kinetic parameter

News : No news

Comment : p.F115S Phe115Ser Chen et al. mutated the homologous aa in Lucilia cuprina AChE

References (3)

Title : The acetylcholinesterase gene and organophosphorus resistance in the Australian sheep blowfly, Lucilia cuprina - Chen_2001_Insect.Biochem.Mol.Biol_31_805
Author(s) : Chen Z , Newcomb RD , Forbes E , McKenzie J , Batterham P
Ref : Insect Biochemistry & Molecular Biology , 31 :805 , 2001
Abstract : Chen_2001_Insect.Biochem.Mol.Biol_31_805
ESTHER : Chen_2001_Insect.Biochem.Mol.Biol_31_805
PubMedSearch : Chen_2001_Insect.Biochem.Mol.Biol_31_805
PubMedID: 11378416
Gene_locus related to this paper: luccu-ACHE

Title : A putative kinetic model for substrate metabolisation by Drosophila acetylcholinesterase - Stojan_1998_FEBS.Lett_440_85
Author(s) : Stojan J , Marcel V , Estrada-Mondaca S , Klaebe A , Masson P , Fournier D
Ref : FEBS Letters , 440 :85 , 1998
Abstract : Stojan_1998_FEBS.Lett_440_85
ESTHER : Stojan_1998_FEBS.Lett_440_85
PubMedSearch : Stojan_1998_FEBS.Lett_440_85
PubMedID: 9862431

Title : Resistance-associated point mutations in insecticide-insensitive acetylcholinesterase - Mutero_1994_Proc.Natl.Acad.Sci.U.S.A_91_5922
Author(s) : Mutero A , Pralavorio M , Bride JM , Fournier D
Ref : Proceedings of the National Academy of Sciences of the United States of America , 91 :5922 , 1994
Abstract : Mutero_1994_Proc.Natl.Acad.Sci.U.S.A_91_5922
ESTHER : Mutero_1994_Proc.Natl.Acad.Sci.U.S.A_91_5922
PubMedSearch : Mutero_1994_Proc.Natl.Acad.Sci.U.S.A_91_5922
PubMedID: 8016090