Gene Locus : drome-ACHE
Mode of mutation : Site directed mutagenesis
Disease :
Summary : Insecticide sensitivity Boublik_2002_Protein.Eng_15_43 || Insecticide sensitivity Menozzi_2004_BMC.Evol.Biol_4_4 || Insecticide sensitivity Chen_2001_Insect.Biochem.Mol.Biol_31_805 || OP-resistance OP-resistance lower than multiple mutations,mut found in Saltillo strain together with F115S G303A F368Y Mutero_1994_Proc.Natl.Acad.Sci.U.S.A_91_5922
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification : Insecticide sensitivity || OP-resistance
Torpedo_number : 129
Kinetic Parameter : No kinetic parameter
News : No news
Comment : Mutation I161V in mature protein. Numbering in Boublik et al. 2002 || Chen et al. mutated the homologous aa in Lucilia cuprina AChE || p.Ile199Val
| Title : Mutations of acetylcholinesterase which confer insecticide resistance in Drosophila melanogaster populations - Menozzi_2004_BMC.Evol.Biol_4_4 |
| Author(s) : Menozzi P , Shi MA , Lougarre A , Tang ZH , Fournier D |
| Ref : BMC Evol Biol , 4 :4 , 2004 |
| Abstract : Menozzi_2004_BMC.Evol.Biol_4_4 |
| ESTHER : Menozzi_2004_BMC.Evol.Biol_4_4 |
| PubMedSearch : Menozzi_2004_BMC.Evol.Biol_4_4 |
| PubMedID: 15018651 |
| Title : Acetylcholinesterase alterations reveal the fitness cost of mutations conferring insecticide resistance - Shi_2004_BMC.Evol.Biol_4_5 |
| Author(s) : Shi MA , Lougarre A , Alies C , Fremaux I , Tang ZH , Stojan J , Fournier D |
| Ref : BMC Evol Biol , 4 :5 , 2004 |
| Abstract : Shi_2004_BMC.Evol.Biol_4_5 |
| ESTHER : Shi_2004_BMC.Evol.Biol_4_5 |
| PubMedSearch : Shi_2004_BMC.Evol.Biol_4_5 |
| PubMedID: 15018650 |
| Title : Acetylcholinesterase engineering for detection of insecticide residues - Boublik_2002_Protein.Eng_15_43 |
| Author(s) : Boublik Y , Saint-Aguet P , Lougarre A , Arnaud M , Villatte F , Estrada-Mondaca S , Fournier D |
| Ref : Protein Engineering , 15 :43 , 2002 |
| Abstract : Boublik_2002_Protein.Eng_15_43 |
| ESTHER : Boublik_2002_Protein.Eng_15_43 |
| PubMedSearch : Boublik_2002_Protein.Eng_15_43 |
| PubMedID: 11842237 |
| Title : The acetylcholinesterase gene and organophosphorus resistance in the Australian sheep blowfly, Lucilia cuprina - Chen_2001_Insect.Biochem.Mol.Biol_31_805 |
| Author(s) : Chen Z , Newcomb RD , Forbes E , McKenzie J , Batterham P |
| Ref : Insect Biochemistry & Molecular Biology , 31 :805 , 2001 |
| Abstract : Chen_2001_Insect.Biochem.Mol.Biol_31_805 |
| ESTHER : Chen_2001_Insect.Biochem.Mol.Biol_31_805 |
| PubMedSearch : Chen_2001_Insect.Biochem.Mol.Biol_31_805 |
| PubMedID: 11378416 |
| Gene_locus related to this paper: luccu-ACHE |
| Title : Resistance-associated point mutations in insecticide-insensitive acetylcholinesterase - Mutero_1994_Proc.Natl.Acad.Sci.U.S.A_91_5922 |
| Author(s) : Mutero A , Pralavorio M , Bride JM , Fournier D |
| Ref : Proceedings of the National Academy of Sciences of the United States of America , 91 :5922 , 1994 |
| Abstract : Mutero_1994_Proc.Natl.Acad.Sci.U.S.A_91_5922 |
| ESTHER : Mutero_1994_Proc.Natl.Acad.Sci.U.S.A_91_5922 |
| PubMedSearch : Mutero_1994_Proc.Natl.Acad.Sci.U.S.A_91_5922 |
| PubMedID: 8016090 |