| Title : The dynamic genome of Hydra - Chapman_2010_Nature_464_592 |
| Author(s) : Chapman JA , Kirkness EF , Simakov O , Hampson SE , Mitros T , Weinmaier T , Rattei T , Balasubramanian PG , Borman J , Busam D , Disbennett K , Pfannkoch C , Sumin N , Sutton GG , Viswanathan LD , Walenz B , Goodstein DM , Hellsten U , Kawashima T , Prochnik SE , Putnam NH , Shu S , Blumberg B , Dana CE , Gee L , Kibler DF , Law L , Lindgens D , Martinez DE , Peng J , Wigge PA , Bertulat B , Guder C , Nakamura Y , Ozbek S , Watanabe H , Khalturin K , Hemmrich G , Franke A , Augustin R , Fraune S , Hayakawa E , Hayakawa S , Hirose M , Hwang JS , Ikeo K , Nishimiya-Fujisawa C , Ogura A , Takahashi T , Steinmetz PR , Zhang X , Aufschnaiter R , Eder MK , Gorny AK , Salvenmoser W , Heimberg AM , Wheeler BM , Peterson KJ , Bottger A , Tischler P , Wolf A , Gojobori T , Remington KA , Strausberg RL , Venter JC , Technau U , Hobmayer B , Bosch TC , Holstein TW , Fujisawa T , Bode HR , David CN , Rokhsar DS , Steele RE |
| Ref : Nature , 464 :592 , 2010 |
|
Abstract :
The freshwater cnidarian Hydra was first described in 1702 and has been the object of study for 300 years. Experimental studies of Hydra between 1736 and 1744 culminated in the discovery of asexual reproduction of an animal by budding, the first description of regeneration in an animal, and successful transplantation of tissue between animals. Today, Hydra is an important model for studies of axial patterning, stem cell biology and regeneration. Here we report the genome of Hydra magnipapillata and compare it to the genomes of the anthozoan Nematostella vectensis and other animals. The Hydra genome has been shaped by bursts of transposable element expansion, horizontal gene transfer, trans-splicing, and simplification of gene structure and gene content that parallel simplification of the Hydra life cycle. We also report the sequence of the genome of a novel bacterium stably associated with H. magnipapillata. Comparisons of the Hydra genome to the genomes of other animals shed light on the evolution of epithelia, contractile tissues, developmentally regulated transcription factors, the Spemann-Mangold organizer, pluripotency genes and the neuromuscular junction. |
| PubMedSearch : Chapman_2010_Nature_464_592 |
| PubMedID: 20228792 |
| Gene_locus related to this paper: 9burk-c9y6c0 , 9burk-c9y8q9 , 9burk-c9y9d4 , 9burk-c9ya28 , 9burk-c9yb37 , 9burk-c9ycr9 , 9burk-c9ydq0 , 9burk-c9ydr2 , 9burk-c9yew1 , 9burk-c9yf78 , 9burk-c9ygh2 , 9burk-c9y7j2 |
| Gene_locus | 9burk-c9y6c0 9burk-c9y8q9 9burk-c9y9d4 9burk-c9ya28 9burk-c9yb37 9burk-c9ycr9 9burk-c9ydq0 9burk-c9ydr2 9burk-c9yew1 9burk-c9yf78 9burk-c9ygh2 9burk-c9y7j2 |
| Gene_locus_frgt | 9burk-c9yf11 |
Chapman JA, Kirkness EF, Simakov O, Hampson SE, Mitros T, Weinmaier T, Rattei T, Balasubramanian PG, Borman J, Busam D, Disbennett K, Pfannkoch C, Sumin N, Sutton GG, Viswanathan LD, Walenz B, Goodstein DM, Hellsten U, Kawashima T, Prochnik SE, Putnam NH, Shu S, Blumberg B, Dana CE, Gee L, Kibler DF, Law L, Lindgens D, Martinez DE, Peng J, Wigge PA, Bertulat B, Guder C, Nakamura Y, Ozbek S, Watanabe H, Khalturin K, Hemmrich G, Franke A, Augustin R, Fraune S, Hayakawa E, Hayakawa S, Hirose M, Hwang JS, Ikeo K, Nishimiya-Fujisawa C, Ogura A, Takahashi T, Steinmetz PR, Zhang X, Aufschnaiter R, Eder MK, Gorny AK, Salvenmoser W, Heimberg AM, Wheeler BM, Peterson KJ, Bottger A, Tischler P, Wolf A, Gojobori T, Remington KA, Strausberg RL, Venter JC, Technau U, Hobmayer B, Bosch TC, Holstein TW, Fujisawa T, Bode HR, David CN, Rokhsar DS, Steele RE (2010)
The dynamic genome of Hydra
Nature
464 :592
Chapman JA, Kirkness EF, Simakov O, Hampson SE, Mitros T, Weinmaier T, Rattei T, Balasubramanian PG, Borman J, Busam D, Disbennett K, Pfannkoch C, Sumin N, Sutton GG, Viswanathan LD, Walenz B, Goodstein DM, Hellsten U, Kawashima T, Prochnik SE, Putnam NH, Shu S, Blumberg B, Dana CE, Gee L, Kibler DF, Law L, Lindgens D, Martinez DE, Peng J, Wigge PA, Bertulat B, Guder C, Nakamura Y, Ozbek S, Watanabe H, Khalturin K, Hemmrich G, Franke A, Augustin R, Fraune S, Hayakawa E, Hayakawa S, Hirose M, Hwang JS, Ikeo K, Nishimiya-Fujisawa C, Ogura A, Takahashi T, Steinmetz PR, Zhang X, Aufschnaiter R, Eder MK, Gorny AK, Salvenmoser W, Heimberg AM, Wheeler BM, Peterson KJ, Bottger A, Tischler P, Wolf A, Gojobori T, Remington KA, Strausberg RL, Venter JC, Technau U, Hobmayer B, Bosch TC, Holstein TW, Fujisawa T, Bode HR, David CN, Rokhsar DS, Steele RE (2010)
Nature
464 :592