| Title : Muscarinic M2 antagonists: anthranilamide derivatives with exceptional selectivity and in vivo activity - Clader_2004_Bioorg.Med.Chem_12_319 |
| Author(s) : Clader JW , Billard W , Binch H, 3rd , Chen LY , Crosby G, Jr. , Duffy RA , Ford J , Kozlowski JA , Lachowicz JE , Li S , Liu C , McCombie SW , Vice S , Zhou G , Greenlee WJ |
| Ref : Bioorganic & Medicinal Chemistry , 12 :319 , 2004 |
|
Abstract :
Anthranilamide analogues such as 23 are potent and highly selective muscarinic M2 antagonists that also show good oral bioavailability and in vivo activity. |
| PubMedSearch : Clader_2004_Bioorg.Med.Chem_12_319 |
| PubMedID: 14723952 |
Clader JW, Billard W, Binch H, 3rd, Chen LY, Crosby G, Jr., Duffy RA, Ford J, Kozlowski JA, Lachowicz JE, Li S, Liu C, McCombie SW, Vice S, Zhou G, Greenlee WJ (2004)
Muscarinic M2 antagonists: anthranilamide derivatives with exceptional selectivity and in vivo activity
Bioorganic & Medicinal Chemistry
12 :319
Clader JW, Billard W, Binch H, 3rd, Chen LY, Crosby G, Jr., Duffy RA, Ford J, Kozlowski JA, Lachowicz JE, Li S, Liu C, McCombie SW, Vice S, Zhou G, Greenlee WJ (2004)
Bioorganic & Medicinal Chemistry
12 :319