| Title : Muscarinic M2 antagonists: anthranilamide derivatives with exceptional selectivity and in vivo activity - Clader_2004_Bioorg.Med.Chem_12_319 |
| Author(s) : Clader JW , Billard W , Binch H, 3rd , Chen LY , Crosby G, Jr. , Duffy RA , Ford J , Kozlowski JA , Lachowicz JE , Li S , Liu C , McCombie SW , Vice S , Zhou G , Greenlee WJ |
| Ref : Bioorganic & Medicinal Chemistry , 12 :319 , 2004 |
| Abstract : |
| PubMedSearch : Clader_2004_Bioorg.Med.Chem_12_319 |
| PubMedID: 14723952 |
| Title : Substituted 2-(R)-methyl piperazines as muscarinic M(2) selective ligands - Kozlowski_2002_Bioorg.Med.Chem.Lett_12_791 |
| Author(s) : Kozlowski JA , Zhou G , Tagat JR , Lin SI , McCombie SW , Ruperto VB , Duffy RA , McQuade RA , Crosby G , Taylor LA , Billard W , Binch H , Lachowicz JE |
| Ref : Bioorganic & Medicinal Chemistry Lett , 12 :791 , 2002 |
| Abstract : |
| PubMedSearch : Kozlowski_2002_Bioorg.Med.Chem.Lett_12_791 |
| PubMedID: 11859004 |
| Title : Synthesis and structure-activity relationships of M(2)-selective muscarinic receptor ligands in the 1-[4-(4-arylsulfonyl)-phenylmethyl]-4-(4-piperidinyl)-piperazine family - McCombie_2002_Bioorg.Med.Chem.Lett_12_795 |
| Author(s) : McCombie SW , Lin SI , Tagat JR , Nazareno D , Vice S , Ford J , Asberom T , Leone D , Kozlowski JA , Zhou G , Ruperto VB , Duffy RA , Lachowicz JE |
| Ref : Bioorganic & Medicinal Chemistry Lett , 12 :795 , 2002 |
| Abstract : |
| PubMedSearch : McCombie_2002_Bioorg.Med.Chem.Lett_12_795 |
| PubMedID: 11859005 |
| Title : SCH 57790, a selective muscarinic M(2) receptor antagonist, releases acetylcholine and produces cognitive enhancement in laboratory animals - Carey_2001_Eur.J.Pharmacol_431_189 |
| Author(s) : Carey GJ , Billard W , Binch H , Cohen-Williams M , Crosby G , Grzelak M , Guzik H , Kozlowski JA , Lowe DB , Pond AJ , Tedesco RP , Watkins RW , Coffin VL |
| Ref : European Journal of Pharmacology , 431 :189 , 2001 |
| Abstract : |
| PubMedSearch : Carey_2001_Eur.J.Pharmacol_431_189 |
| PubMedID: 11728425 |
| Title : Metabolic stabilization of benzylidene ketal M(2) muscarinic receptor antagonists via halonaphthoic acid substitution - Boyle_2001_Bioorg.Med.Chem.Lett_11_2311 |
| Author(s) : Boyle CD , Chackalamannil S , Clader JW , Greenlee WJ , Josien HB , Kaminski JJ , Kozlowski JA , McCombie SW , Nazareno DV , Tagat JR , Wang Y , Zhou G , Billard W , Binch H , Crosby G , Cohen-Williams M , Coffin VL , Cox KA , Grotz DE , Duffy RA , Ruperto V , Lachowicz JE |
| Ref : Bioorganic & Medicinal Chemistry Lett , 11 :2311 , 2001 |
| Abstract : |
| PubMedSearch : Boyle_2001_Bioorg.Med.Chem.Lett_11_2311 |
| PubMedID: 11527721 |
| Title : Diphenyl sulfoxides as selective antagonists of the muscarinic M2 receptor - Kozlowski_2000_Bioorg.Med.Chem.Lett_10_2255 |
| Author(s) : Kozlowski JA , Lowe DB , Guzik HS , Zhou G , Ruperto VB , Duffy RA , McQuade R , Crosby G , Taylor LA , Billard W , Binch H , Lachowicz JE |
| Ref : Bioorganic & Medicinal Chemistry Lett , 10 :2255 , 2000 |
| Abstract : |
| PubMedSearch : Kozlowski_2000_Bioorg.Med.Chem.Lett_10_2255 |
| PubMedID: 11055332 |