| Title : The diploid genome sequence of Candida albicans - Jones_2004_Proc.Natl.Acad.Sci.U.S.A_101_7329 |
| Author(s) : Jones T , Federspiel NA , Chibana H , Dungan J , Kalman S , Magee BB , Newport G , Thorstenson YR , Agabian N , Magee PT , Davis RW , Scherer S |
| Ref : Proc Natl Acad Sci U S A , 101 :7329 , 2004 |
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Abstract :
We present the diploid genome sequence of the fungal pathogen Candida albicans. Because C. albicans has no known haploid or homozygous form, sequencing was performed as a whole-genome shotgun of the heterozygous diploid genome in strain SC5314, a clinical isolate that is the parent of strains widely used for molecular analysis. We developed computational methods to assemble a diploid genome sequence in good agreement with available physical mapping data. We provide a whole-genome description of heterozygosity in the organism. Comparative genomic analyses provide important clues about the evolution of the species and its mechanisms of pathogenesis. |
| PubMedSearch : Jones_2004_Proc.Natl.Acad.Sci.U.S.A_101_7329 |
| PubMedID: 15123810 |
| Gene_locus related to this paper: canal-apth1 , canal-ATG15 , canal-bna7 , canal-c4yl13 , canal-cbpy , canal-LIP1 , canal-LIP2 , canal-LIP3 , canal-LIP4 , canal-LIP5 , canal-LIP6 , canal-LIP7 , canal-LIP8 , canal-LIP9 , canal-LIP10 , canal-ppme1 , canal-q5a0c9 , canal-q5a0i7 , canal-q5a2i9 , canal-q5a2u7 , canal-q5a6l4 , canal-q5a042 , canal-q5a948 , canal-q5aa97 , canal-q5abf2 , canal-q5acl5 , canal-q5ad17 , canal-q5adx4 , canal-q5ady2 , canal-q5aeu3 , canal-q5afp8 , canal-q5ag57 , canal-q5ah37 , canal-q5ai09 , canal-q5ai12 , canal-q5ai87 , canal-q5ajt3 , canal-q5ak09 , canal-q5ak29 , canal-q5ak96 , canal-q5akr2 , canal-q5akz5 , canal-q5amg8 , canal-q5amn4 , canal-q5amn7 , canal-q5ams2 , canal-q5ams7 , canal-q5apu4 , canal-q59k70 , canal-q59kl3 , canal-q59l46 , canal-q59ln6 , canal-q59m48 , canal-q59ng0 , canal-q59nl9 , canal-q59nw6 , canal-q59nx4 , canal-q59nx8 , canal-q59s22 , canal-q59tt5 , canal-q59u61 , canal-q59u64 , canal-q59vf1 , canal-q59vp0 , canal-q59we9 , canal-q59xq6 , canal-q59y42 , canal-q59y97 , canaw-c4yrr3 , canal-hda1 |
Jones T, Federspiel NA, Chibana H, Dungan J, Kalman S, Magee BB, Newport G, Thorstenson YR, Agabian N, Magee PT, Davis RW, Scherer S (2004)
The diploid genome sequence of Candida albicans
Proc Natl Acad Sci U S A
101 :7329
Jones T, Federspiel NA, Chibana H, Dungan J, Kalman S, Magee BB, Newport G, Thorstenson YR, Agabian N, Magee PT, Davis RW, Scherer S (2004)
Proc Natl Acad Sci U S A
101 :7329