| Title : Prophylaxis and Post-exposure Treatment of Intoxications Caused by Nerve Agents and Organophosphorus Pesticides - Kuca_2013_Mini.Rev.Med.Chem_13_2102 |
| Author(s) : Kuca K , Jun D , Musilek K , Pohanka M , Karasova JZ , Soukup O |
| Ref : Mini Rev Med Chem , 13 :2102 , 2013 |
| Abstract : Treatment of intoxications caused by nerve agents and organophosphorus pesticides consists of different approaches. The first approach is called prophylaxis or pre-exposure administration of antidotes such as cholinesterase reactivators or bioscavengers. The second, post-exposure treatment consists of anticholinergic drugs, acetylcholinesterase reactivators and anticonvulsants. This article is aimed at both mentioned approaches, especially focused on cholinesterase reactivators, which are a broad group of structurally different compounds that can be used in prophylaxis (separately or in combination with butyrylcholinesterase) and also as post-exposure treatment. |
| ESTHER : Kuca_2013_Mini.Rev.Med.Chem_13_2102 |
| PubMedSearch : Kuca_2013_Mini.Rev.Med.Chem_13_2102 |
| PubMedID: 24195661 |
Kuca K, Jun D, Musilek K, Pohanka M, Karasova JZ, Soukup O (2013)
Prophylaxis and Post-exposure Treatment of Intoxications Caused by Nerve Agents and Organophosphorus Pesticides
Mini Rev Med Chem
13 :2102
Kuca K, Jun D, Musilek K, Pohanka M, Karasova JZ, Soukup O (2013)
Mini Rev Med Chem
13 :2102