Toh_2015_Science_350_203

Reference

Title : Structure-function analysis identifies highly sensitive strigolactone receptors in Striga - Toh_2015_Science_350_203
Author(s) : Toh S , Holbrook-Smith D , Stogios PJ , Onopriyenko O , Lumba S , Tsuchiya Y , Savchenko A , McCourt P
Ref : Science , 350 :203 , 2015
Abstract :

Strigolactones are naturally occurring signaling molecules that affect plant development, fungi-plant interactions, and parasitic plant infestations. We characterized the function of 11 strigolactone receptors from the parasitic plant Striga hermonthica using chemical and structural biology. We found a clade of polyspecific receptors, including one that is sensitive to picomolar concentrations of strigolactone. A crystal structure of a highly sensitive strigolactone receptor from Striga revealed a larger binding pocket than that of the Arabidopsis receptor, which could explain the increased range of strigolactone sensitivity. Thus, the sensitivity of Striga to strigolactones from host plants is driven by receptor sensitivity. By expressing strigolactone receptors in Arabidopsis, we developed a bioassay that can be used to identify chemicals and crops with altered strigolactone levels.

PubMedSearch : Toh_2015_Science_350_203
PubMedID: 26450211
Gene_locus related to this paper: strhe-ShHTL2 , strhe-ShHTL10 , strhe-ShHTL6 , strhe-ShHTL9 , strhe-ShHTL8 , strhe-ShHTL11 , strhe-ShHTL4 , strhe-ShHTL1 , strhe-ShHTL7 , strhe-ShHTL3 , strhe-ShHTL5

Related information

Gene_locus strhe-ShHTL2    strhe-ShHTL10    strhe-ShHTL6    strhe-ShHTL9    strhe-ShHTL8    strhe-ShHTL11    strhe-ShHTL4    strhe-ShHTL1    strhe-ShHTL7    strhe-ShHTL3    strhe-ShHTL5
Family strhe-ShHTL2    strhe-ShHTL10    strhe-ShHTL6    strhe-ShHTL9    strhe-ShHTL8    strhe-ShHTL11    strhe-ShHTL4    strhe-ShHTL1    strhe-ShHTL7    strhe-ShHTL3    strhe-ShHTL5    RsbQ-like
Structure strhe-ShHTL2    strhe-ShHTL10    strhe-ShHTL6    strhe-ShHTL9    strhe-ShHTL8    strhe-ShHTL11    strhe-ShHTL4    strhe-ShHTL1    strhe-ShHTL7    strhe-ShHTL3    strhe-ShHTL5    RsbQ-like    5CBK

Citations formats

Toh S, Holbrook-Smith D, Stogios PJ, Onopriyenko O, Lumba S, Tsuchiya Y, Savchenko A, McCourt P (2015)
Structure-function analysis identifies highly sensitive strigolactone receptors in Striga
Science 350 :203

Toh S, Holbrook-Smith D, Stogios PJ, Onopriyenko O, Lumba S, Tsuchiya Y, Savchenko A, McCourt P (2015)
Science 350 :203