RsbQ-like

Relationship

Family: RsbQ-like

Block: X

Parent Family: Abhydrolase_6

Comment

The RsbQ alpha/beta hydrolase and RsbP serine phosphatase form a signaling pair required to activate the general stress factor Sigma factor sigb of Bacillus subtilis in response to energy limitation. In plants RsbQ-like proteins could function downstream of strigolactone synthesis (Strigolactones are endogenous butenolide hormones that regulate shoot and root architecture, and stimulate the branching of arbuscular mycorrhizal fungi). DWARF14(D14) act as component of hormone signaling or as enzymes that participates in the conversion of strigolactones to the bioactive form. Karrikins (KARs) represent a family of butenolide compounds found in smoke that trigger the germination of many species after fire. KAI2 (karrikin-insensitive2) is required for normal seed germination and seedling growth. Conn et al. showed that convergent evolution of strigolactone perception enabled host detection in parasitic plants. Mutations in KAI2, encoding the proposed karrikin receptor, result in hypersensitivity to water deprivation.. The parasite Striga hermonthica is causing severe yield losses of cereals in sub-Saharan Africa. The germination of Striga seeds relies on host-released strigolactones (SLs) signaling molecules. SL analogs are developped as 'suicidal germination agents'(The induction of Striga seeds germination in the absence of the host leads to the death of germinating parasite). Wang et al. show that origins of strigolactone and karrikin signaling in plants could come from horizontal transfer from bacteria. The fungi D14 Fungal-D14-Strigolactone-R although homologous to family RsbQ-like of plant strigolactone receptors are somewhat far related and cannot supplement lack of receptor in arabidopsis for example. However Bacillus subtilis RsbQ is a functional butenolide hydrolase Melville et al.

Database

Interpro : IPR031143 Strigolactone esterase D14 family D14_fam

PIRSF : No PIRSF

Pdoc : No Pdoc

Pfam : PF12697 Abhydrolase_6

Prints : No Print

EC Number : No EC Number

Sequences

Peptide in Fasta
Nucleotide in Fasta
Alignment with Multalin Text only
Seed alignment with MAFFT No colour
Alignment with MAFFT No colour
Dendrogram The dnd file

Structures (67)

Genes Proteins in RsbQ-like family (207)

Fragments of genes in RsbQ-like family (8)

Structures in RsbQ-like family (67)

Substrates in RsbQ-like family (44)

Inhibitors in RsbQ-like family (35)

References (33)

Title : KAI2 can do: Karrikin Receptor Function in Plant Development and Response to Abiotic and Biotic Factors - Varshney_2023_Plant.Cell.Physiol__
Author(s) : Varshney K , Gutjahr C
Ref : Plant Cell Physiol , : , 2023
PubMedID: 37548562

Title : Strigolactones: diversity, perception, and hydrolysis - Guercio_2023_Phytochem.Rev_22_339
Author(s) : Guercio AM , Palayam M , Shabek N
Ref : Phytochemistry Review , 22 :339 , 2023
PubMedID: 37201177

Title : Perception of butenolides by Bacillus subtilis via the alpha\/beta hydrolase RsbQ - Melville_2023_Curr.Biol__
Author(s) : Melville KT , Kamran M , Yao J , Costa M , Holland M , Taylor NL , Fritz G , Flematti GR , Waters MT
Ref : Current Biology , : , 2023
PubMedID: 38183985
Gene_locus related to this paper: bacsu-RsbQ

Title : A structural homologue of the plant receptor D14 mediates responses to strigolactones in the fungal phytopathogen Cryphonectria parasitica - Fiorilli_2022_New.Phytol__
Author(s) : Fiorilli V , Forgia M , de Saint Germain A , D'Arrigo G , Cornu D , Le Bris P , Al-Babili S , Cardinale F , Prandi C , Spyrakis F , Boyer FD , Turina M , Lanfranco L
Ref : New Phytol , : , 2022
PubMedID: 35119708
Gene_locus related to this paper: crypa-CpD14

Title : Origins of strigolactone and karrikin signaling in plants - Wang_2021_Trends.Plant.Sci__
Author(s) : Wang Q , Smith SM , Huang J
Ref : Trends Plant Sci , : , 2021
PubMedID: 34876337

Title : Identification of Conserved and Divergent Strigolactone Receptors in Sugarcane Reveals a Key Residue Crucial for Plant Branching Control - Hu_2021_Front.Plant.Sci_12_747160
Author(s) : Hu A , Zhao Q , Chen L , Zhao J , Wang Y , Feng K , Wu L , Xie M , Zhou X , Xiao L , Ming Z , Zhang M , Yao R
Ref : Front Plant Sci , 12 :747160 , 2021
PubMedID: 34858455
Gene_locus related to this paper: 9poal-a0a0d5nt23

Title : Comparing and Contrasting the Multiple Roles of Butenolide Plant Growth Regulators: Strigolactones and Karrikins in Plant Development and Adaptation to Abiotic Stresses - Yang_2019_Int.J.Mol.Sci_20_
Author(s) : Yang T , Lian Y , Wang C
Ref : Int J Mol Sci , 20 : , 2019
PubMedID: 31842355

Title : Impairment in karrikin but not strigolactone sensing enhances root skewing in Arabidopsis thaliana - Swarbreck_2019_Plant.J_98_607
Author(s) : Swarbreck SM , Guerringue Y , Matthus E , Jamieson FJC , Davies JM
Ref : Plant J , 98 :607 , 2019
PubMedID: 30659713

Title : Strigolactone perception and deactivation by a hydrolase receptor DWARF14 - Seto_2019_Nat.Commun_10_191
Author(s) : Seto Y , Yasui R , Kameoka H , Tamiru M , Cao M , Terauchi R , Sakurada A , Hirano R , Kisugi T , Hanada A , Umehara M , Seo E , Akiyama K , Burke J , Takeda-Kamiya N , Li W , Hirano Y , Hakoshima T , Mashiguchi K , Noel JP , Kyozuka J , Yamaguchi S
Ref : Nat Commun , 10 :191 , 2019
PubMedID: 30643123
Gene_locus related to this paper: arath-AtD14

Title : Strigolactone promotes cytokinin degradation through transcriptional activation of CYTOKININ OXIDASE\/DEHYDROGENASE 9 in rice - Duan_2019_Proc.Natl.Acad.Sci.U.S.A_116_14319
Author(s) : Duan J , Yu H , Yuan K , Liao Z , Meng X , Jing Y , Liu G , Chu J , Li J
Ref : Proc Natl Acad Sci U S A , 116 :14319 , 2019
PubMedID: 31235564

Title : Binding or Hydrolysis? How Does the Strigolactone Receptor Work? - Marzec_2019_Trends.Plant.Sci_24_571
Author(s) : Marzec M , Brewer P
Ref : Trends Plant Sci , 24 :571 , 2019
PubMedID: 31151745

Title : Strigolactones cross the kingdoms: plants, fungi, and bacteria in the arbuscular mycorrhizal symbiosis - Lanfranco_2018_J.Exp.Bot_69_2175
Author(s) : Lanfranco L , Fiorilli V , Venice F , Bonfante P
Ref : J Exp Bot , 69 :2175 , 2018
PubMedID: 29309622

Title : Rationally Designed Strigolactone Analogs as Antagonists of the D14 Receptor - Takeuchi_2018_Plant.Cell.Physiol_59_1545
Author(s) : Takeuchi J , Jiang K , Hirabayashi K , Imamura Y , Wu Y , Xu Y , Miyakawa T , Nakamura H , Tanokura M , Asami T
Ref : Plant Cell Physiol , 59 :1545 , 2018
PubMedID: 29727000
Gene_locus related to this paper: arath-AtD14 , arath-KAI2.D14L

Title : Irreversible strigolactone recognition: a non-canonical mechanism for hormone perception - Yao_2018_Curr.Opin.Plant.Biol_45_155
Author(s) : Yao R , Chen L , Xie D
Ref : Curr Opin Plant Biol , 45 :155 , 2018
PubMedID: 30014890
Gene_locus related to this paper: arath-AtD14

Title : Found in Translation: Applying Lessons from Model Systems to Strigolactone Signaling in Parasitic Plants - Lumba_2017_Trends.Biochem.Sci_42_556
Author(s) : Lumba S , Subha A , McCourt P
Ref : Trends in Biochemical Sciences , 42 :556 , 2017
PubMedID: 28495334

Title : The karrikin receptor KAI2 promotes drought resistance in Arabidopsis thaliana - Li_2017_PLoS.Genet_13_e1007076
Author(s) : Li W , Nguyen KH , Chu HD , Ha CV , Watanabe Y , Osakabe Y , Leyva-Gonzalez MA , Sato M , Toyooka K , Voges L , Tanaka M , Mostofa MG , Seki M , Seo M , Yamaguchi S , Nelson DC , Tian C , Herrera-Estrella L , Tran LP
Ref : PLoS Genet , 13 :e1007076 , 2017
PubMedID: 29131815
Gene_locus related to this paper: arath-KAI2.D14L

Title : Evolution of strigolactone receptors by gradual neo-functionalization of KAI2 paralogues - Bythell-Douglas_2017_BMC.Biol_15_52
Author(s) : Bythell-Douglas R , Rothfels CJ , Stevenson DWD , Graham SW , Wong GK , Nelson DC , Bennett T
Ref : BMC Biol , 15 :52 , 2017
PubMedID: 28662667

Title : Structural modelling and transcriptional responses highlight a clade of PpKAI2-LIKE genes as candidate receptors for strigolactones in Physcomitrella patens - Lopez-Obando_2016_Planta_243_1441
Author(s) : Lopez-Obando M , Conn CE , Hoffmann B , Bythell-Douglas R , Nelson DC , Rameau C , Bonhomme S
Ref : Planta , 243 :1441 , 2016
PubMedID: 26979323

Title : Smoke and Hormone Mirrors: Action and Evolution of Karrikin and Strigolactone Signaling - Morffy_2016_Trends.Genet_32_176
Author(s) : Morffy N , Faure L , Nelson DC
Ref : Trends Genet , 32 :176 , 2016
PubMedID: 26851153

Title : Suicidal germination for parasitic weed control - Zwanenburg_2016_Pest.Manag.Sci_72_2016
Author(s) : Zwanenburg B , Mwakaboko AS , Kannan C
Ref : Pest Manag Sci , 72 :2016 , 2016
PubMedID: 26733056

Title : Structure-function analysis identifies highly sensitive strigolactone receptors in Striga - Toh_2015_Science_350_203
Author(s) : Toh S , Holbrook-Smith D , Stogios PJ , Onopriyenko O , Lumba S , Tsuchiya Y , Savchenko A , McCourt P
Ref : Science , 350 :203 , 2015
PubMedID: 26450211
Gene_locus related to this paper: strhe-ShHTL2 , strhe-ShHTL10 , strhe-ShHTL6 , strhe-ShHTL9 , strhe-ShHTL8 , strhe-ShHTL11 , strhe-ShHTL4 , strhe-ShHTL1 , strhe-ShHTL7 , strhe-ShHTL3 , strhe-ShHTL5

Title : The Structure of the Karrikin-Insensitive Protein (KAI2) in Arabidopsis thaliana. - Bythell-Douglas_2013_PLoS.One_8_e54758
Author(s) : Bythell-Douglas R , Waters MT , Scaffidi A , Flematti GR , Smith SM , Bond CS
Ref : PLoS ONE , 8 :e54758 , 2013
PubMedID: 23349965
Gene_locus related to this paper: arath-KAI2.D14L

Title : KAI2- and MAX2-Mediated Responses to Karrikins and Strigolactones Are Largely Independent of HY5 in Arabidopsis Seedlings - Waters_2013_Mol.Plant_6_63
Author(s) : Waters MT , Smith SM
Ref : Mol Plant , 6 :63 , 2013
PubMedID: 23142794
Gene_locus related to this paper: arath-KAI2.D14L

Title : Structures of D14 and D14L in the strigolactone and karrikin signaling pathways - Kagiyama_2013_Genes.Cells_18_147
Author(s) : Kagiyama M , Hirano Y , Mori T , Kim SY , Kyozuka J , Seto Y , Yamaguchi S , Hakoshima T
Ref : Genes Cells , 18 :147 , 2013
PubMedID: 23301669
Gene_locus related to this paper: arath-KAI2.D14L , orysj-Q10QA5

Title : Molecular mechanism of strigolactone perception by DWARF14 - Nakamura_2013_Nat.Commun_4_2613
Author(s) : Nakamura H , Xue YL , Miyakawa T , Hou F , Qin HM , Fukui K , Shi X , Ito E , Ito S , Park SH , Miyauchi Y , Asano A , Totsuka N , Ueda T , Tanokura M , Asami T
Ref : Nat Commun , 4 :2613 , 2013
PubMedID: 24131983
Gene_locus related to this paper: orysj-Q10QA5

Title : DAD2 Is an alpha\/beta Hydrolase Likely to Be Involved in the Perception of the Plant Branching Hormone, Strigolactone - Hamiaux_2012_Curr.Biol_22_2032
Author(s) : Hamiaux C , Drummond RS , Janssen BJ , Ledger SE , Cooney JM , Newcomb RD , Snowden KC
Ref : Current Biology , 22 :2032 , 2012
PubMedID: 22959345
Gene_locus related to this paper: pethy-dad2

Title : Specialisation within the DWARF14 protein family confers distinct responses to karrikins and strigolactones in Arabidopsis. - Waters_2012_Development_139_1285
Author(s) : Waters MT , Nelson DC , Scaffidi A , Flematti GR , Sun YK , Dixon KW , Smith SM
Ref : Development , 139 :1285 , 2012
PubMedID: 22357928
Gene_locus related to this paper: arath-AtD14 , arath-KAI2.D14L , orysj-q10j20 , orysj-Q10QA5

Title : Dwarf 88, a novel putative esterase gene affecting architecture of rice plant - Gao_2009_Plant.Mol.Biol_71_265
Author(s) : Gao Z , Qian Q , Liu X , Yan M , Feng Q , Dong G , Liu J , Han B
Ref : Plant Mol Biol , 71 :265 , 2009
PubMedID: 19603144
Gene_locus related to this paper: orysj-Q10QA5

Title : Identification and characterization of HTD2: a novel gene negatively regulating tiller bud outgrowth in rice - Liu_2009_Planta_230_649
Author(s) : Liu W , Wu C , Fu Y , Hu G , Si H , Zhu L , Luan W , He Z , Sun Z
Ref : Planta , 230 :649 , 2009
PubMedID: 19579033
Gene_locus related to this paper: orysj-Q10QA5

Title : d14, a strigolactone-insensitive mutant of rice, shows an accelerated outgrowth of tillers - Arite_2009_Plant.Cell.Physiol_50_1416
Author(s) : Arite T , Umehara M , Ishikawa S , Hanada A , Maekawa M , Yamaguchi S , Kyozuka J
Ref : Plant Cell Physiol , 50 :1416 , 2009
PubMedID: 19542179
Gene_locus related to this paper: orysj-Q10QA5

Title : Crystal structures of RsbQ, a stress-response regulator in Bacillus subtilis - Kaneko_2005_Protein.Sci_14_558
Author(s) : Kaneko T , Tanaka N , Kumasaka T
Ref : Protein Science , 14 :558 , 2005
PubMedID: 15632289
Gene_locus related to this paper: bacsu-RsbQ

Title : Catalytic function of an alpha\/beta hydrolase is required for energy stress activation of the sigma(B) transcription factor in Bacillus subtilis - Brody_2001_J.Bacteriol_183_6422
Author(s) : Brody MS , Vijay K , Price CW
Ref : Journal of Bacteriology , 183 :6422 , 2001
PubMedID: 11591687
Gene_locus related to this paper: bacsu-RsbQ