strhe-ShHTL7

Striga hermonthica (Purple witchweed) (Buchnera hermonthica) hyposensitive to light 7

Comment

hydrolyze SL and mediate the SL-induced seed germination. The most active receptor

Relationship

Family : RsbQ-like

Block : X

Position in NCBI Life Tree : Striga hermonthica

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Viridiplantae N E > Streptophyta N E > Streptophytina N E > Embryophyta N E > Tracheophyta N E > Euphyllophyta N E > Spermatophyta N E > Magnoliophyta N E > Mesangiospermae N E > eudicotyledons N E > Gunneridae N E > Pentapetalae N E > asterids N E > lamiids N E > Lamiales N E > Orobanchaceae N E > Buchnereae N E > Striga N E > Striga hermonthica N E > cellular organisms N E > Eukaryota N E > Viridiplantae N E > Streptophyta N E > Streptophytina N E > Embryophyta N E > Tracheophyta N E > Euphyllophyta N E > Spermatophyta N E > Magnoliophyta N E > Mesangiospermae N E > eudicotyledons N E > Gunneridae N E > Pentapetalae N E > asterids N E > lamiids N E > Lamiales N E > Orobanchaceae N E > Buchnereae N E > Striga N E > Striga hermonthica N E > cellular organisms N E > Eukaryota N E > Viridiplantae N E > Streptophyta N E > Streptophytina N E > Embryophyta N E > Tracheophyta N E > Euphyllophyta N E > Spermatophyta N E > Magnoliophyta N E > Mesangiospermae N E > eudicotyledons N E > Gunneridae N E > Pentapetalae N E > asterids N E > lamiids N E > Lamiales N E > Orobanchaceae N E > Buchnereae N E > Striga N E > Striga hermonthica N E

Molecular evidence

No mutation

5Z7Y - Crystal structure of the strigolactone receptor from Striga hermonthica HTL7 (ShHTL7) 5Z7Y - Crystal structure of the strigolactone receptor from Striga hermonthica HTL7 (ShHTL7) 5Z7Y - Crystal structure of the strigolactone receptor from Striga hermonthica HTL7 (ShHTL7) 5Z82 - Structural basis for specific inhibition of highly sensitive strigolactone receptor ShHTL7 from Striga hermonthica 5Z82 - Structural basis for specific inhibition of highly sensitive strigolactone receptor ShHTL7 from Striga hermonthica 5Z82 - Structural basis for specific inhibition of highly sensitive strigolactone receptor ShHTL7 from Striga hermonthica 5Z89 - Structural basis for specific inhibition of highly sensitive strigolactone receptor ShHTL7 from Striga hermonthica(with Triton X100) 5Z89 - Structural basis for specific inhibition of highly sensitive strigolactone receptor ShHTL7 from Striga hermonthica(with Triton X100) 5Z89 - Structural basis for specific inhibition of highly sensitive strigolactone receptor ShHTL7 from Striga hermonthica(with Triton X100) 5Z8P - Structural basis for specific inhibition of highly sensitive strigolactone receptor ShHTL7 from Striga hermonthica 5Z8P - Structural basis for specific inhibition of highly sensitive strigolactone receptor ShHTL7 from Striga hermonthica 5Z8P - Structural basis for specific inhibition of highly sensitive strigolactone receptor ShHTL7 from Striga hermonthica 5Z95 - Structural basis for specific inhibition of highly sensitive strigolactone receptor ShHTL7 from Striga hermonthica (with Triton X100) 5Z95 - Structural basis for specific inhibition of highly sensitive strigolactone receptor ShHTL7 from Striga hermonthica (with Triton X100) 5Z95 - Structural basis for specific inhibition of highly sensitive strigolactone receptor ShHTL7 from Striga hermonthica (with Triton X100) 6A9D - Crystal structure of the strigolactone receptor ShHTL7 from Striga hermonthica 6A9D - Crystal structure of the strigolactone receptor ShHTL7 from Striga hermonthica 6A9D - Crystal structure of the strigolactone receptor ShHTL7 from Striga hermonthica 7C8L - Hybrid designing of potent inhibitors of Striga strigolactone receptor ShHTL7 7C8L - Hybrid designing of potent inhibitors of Striga strigolactone receptor ShHTL7 7C8L - Hybrid designing of potent inhibitors of Striga strigolactone receptor ShHTL7 7SNU - Crystal structure of ShHTL7 from Striga hermonthica in complex with strigolactone antagonist RG6 7SNU - Crystal structure of ShHTL7 from Striga hermonthica in complex with strigolactone antagonist RG6 7SNU - Crystal structure of ShHTL7 from Striga hermonthica in complex with strigolactone antagonist RG6 7WA8 - Strigolactone receptors in Striga ShHTL7 7WA8 - Strigolactone receptors in Striga ShHTL7 7WA8 - Strigolactone receptors in Striga ShHTL7

No kinetic

No disease

Database

Sequence

Peptide

MSSIGLAHNV TILGSGETTV VLGHGYGTDQ SVWKLLVPYL VDDYKVLLYD HMGAGTTNPD YFDFDRYSSL EGYSYDLIAI LEEFQVSKCI YVGHSMSSMA AAVASIFRPD LFHKLVMISP TPRLINTEEY YGGFEQKVMD ETLRSLDENF KSLSLGTAPL LLACDLESAA MQEYCRTLFN MRPDIACCIT RMICGLDLRP YLGHVTVPCH IIQSSNDIMV PVAVGEYLRK NLGGPSVVEV MPTEGHLPHL SMPEVTIPVV LRHIRQDITD H

References (27)

Title : Mechanistic basis for enhanced strigolactone sensitivity in KAI2 triple mutant - Sobecks_2025_Biophys.J_124_1908
Author(s) : Sobecks BL , Chen J , Dean TJ , Shukla D
Ref : Biophysical Journal , 124 :1908 , 2025
Abstract :
PubMedSearch : Sobecks_2025_Biophys.J_124_1908
PubMedID: 40269499
Gene_locus related to this paper: strhe-ShHTL7 , arath-KAI2.D14L

Title : Mechanistic basis for enhanced strigolactone sensitivity in KAI2 triple mutant - Sobecks_2025_Biophys.J_124_1908
Author(s) : Sobecks BL , Chen J , Dean TJ , Shukla D
Ref : Biophysical Journal , 124 :1908 , 2025
Abstract :
PubMedSearch : Sobecks_2025_Biophys.J_124_1908
PubMedID: 40269499
Gene_locus related to this paper: strhe-ShHTL7 , arath-KAI2.D14L

Title : Mechanistic basis for enhanced strigolactone sensitivity in KAI2 triple mutant - Sobecks_2025_Biophys.J_124_1908
Author(s) : Sobecks BL , Chen J , Dean TJ , Shukla D
Ref : Biophysical Journal , 124 :1908 , 2025
Abstract :
PubMedSearch : Sobecks_2025_Biophys.J_124_1908
PubMedID: 40269499
Gene_locus related to this paper: strhe-ShHTL7 , arath-KAI2.D14L

Title : A novel strigolactone receptor antagonist provides insights into the structural inhibition, conditioning, and germination of the crop parasite Striga - Arellano-Saab_2022_J.Biol.Chem_298_101734
Author(s) : Arellano-Saab A , McErlean CSP , Lumba S , Savchenko A , Stogios PJ , McCourt P
Ref : Journal of Biological Chemistry , :101734 , 2022
Abstract :
PubMedSearch : Arellano-Saab_2022_J.Biol.Chem_298_101734
PubMedID: 35181340
Gene_locus related to this paper: strhe-ShHTL7

Title : Rational design of Striga hermonthica-specific seed germination inhibitors - Zarban_2022_Plant.Physiol_188_1369
Author(s) : Zarban RA , Shahul Hameed UF , Jamil M , Ota T , Wang JY , Arold ST , Asami T , Al-Babili S
Ref : Plant Physiol , 188 :1369 , 2022
Abstract :
PubMedSearch : Zarban_2022_Plant.Physiol_188_1369
PubMedID: 34850204
Gene_locus related to this paper: strhe-ShHTL7

Title : A novel strigolactone receptor antagonist provides insights into the structural inhibition, conditioning, and germination of the crop parasite Striga - Arellano-Saab_2022_J.Biol.Chem_298_101734
Author(s) : Arellano-Saab A , McErlean CSP , Lumba S , Savchenko A , Stogios PJ , McCourt P
Ref : Journal of Biological Chemistry , :101734 , 2022
Abstract :
PubMedSearch : Arellano-Saab_2022_J.Biol.Chem_298_101734
PubMedID: 35181340
Gene_locus related to this paper: strhe-ShHTL7

Title : A novel strigolactone receptor antagonist provides insights into the structural inhibition, conditioning, and germination of the crop parasite Striga - Arellano-Saab_2022_J.Biol.Chem_298_101734
Author(s) : Arellano-Saab A , McErlean CSP , Lumba S , Savchenko A , Stogios PJ , McCourt P
Ref : Journal of Biological Chemistry , :101734 , 2022
Abstract :
PubMedSearch : Arellano-Saab_2022_J.Biol.Chem_298_101734
PubMedID: 35181340
Gene_locus related to this paper: strhe-ShHTL7

Title : Rational design of Striga hermonthica-specific seed germination inhibitors - Zarban_2022_Plant.Physiol_188_1369
Author(s) : Zarban RA , Shahul Hameed UF , Jamil M , Ota T , Wang JY , Arold ST , Asami T , Al-Babili S
Ref : Plant Physiol , 188 :1369 , 2022
Abstract :
PubMedSearch : Zarban_2022_Plant.Physiol_188_1369
PubMedID: 34850204
Gene_locus related to this paper: strhe-ShHTL7

Title : Rational design of Striga hermonthica-specific seed germination inhibitors - Zarban_2022_Plant.Physiol_188_1369
Author(s) : Zarban RA , Shahul Hameed UF , Jamil M , Ota T , Wang JY , Arold ST , Asami T , Al-Babili S
Ref : Plant Physiol , 188 :1369 , 2022
Abstract :
PubMedSearch : Zarban_2022_Plant.Physiol_188_1369
PubMedID: 34850204
Gene_locus related to this paper: strhe-ShHTL7

Title : Molecular basis for high ligand sensitivity and selectivity of strigolactone receptors in Striga - Wang_2021_Plant.Physiol_185_1411
Author(s) : Wang Y , Yao R , Du X , Guo L , Chen L , Xie D , Smith SM
Ref : Plant Physiol , 185 :1411 , 2021
Abstract :
PubMedSearch : Wang_2021_Plant.Physiol_185_1411
PubMedID: 33793945
Gene_locus related to this paper: strhe-ShHTL7

Title : Molecular basis for high ligand sensitivity and selectivity of strigolactone receptors in Striga - Wang_2021_Plant.Physiol_185_1411
Author(s) : Wang Y , Yao R , Du X , Guo L , Chen L , Xie D , Smith SM
Ref : Plant Physiol , 185 :1411 , 2021
Abstract :
PubMedSearch : Wang_2021_Plant.Physiol_185_1411
PubMedID: 33793945
Gene_locus related to this paper: strhe-ShHTL7

Title : Molecular basis for high ligand sensitivity and selectivity of strigolactone receptors in Striga - Wang_2021_Plant.Physiol_185_1411
Author(s) : Wang Y , Yao R , Du X , Guo L , Chen L , Xie D , Smith SM
Ref : Plant Physiol , 185 :1411 , 2021
Abstract :
PubMedSearch : Wang_2021_Plant.Physiol_185_1411
PubMedID: 33793945
Gene_locus related to this paper: strhe-ShHTL7

Title : Structural analysis of HTL and D14 proteins reveals the basis for ligand selectivity in Striga - Xu_2018_Nat.Commun_9_3947
Author(s) : Xu Y , Miyakawa T , Nosaki S , Nakamura A , Lyu Y , Nakamura H , Ohto U , Ishida H , Shimizu T , Asami T , Tanokura M
Ref : Nat Commun , 9 :3947 , 2018
Abstract :
PubMedSearch : Xu_2018_Nat.Commun_9_3947
PubMedID: 30258184
Gene_locus related to this paper: strhe-ShD14 , strhe-ShHTL4 , strhe-ShHTL1 , strhe-ShHTL7

Title : Structural basis for specific inhibition of the highly sensitive ShHTL7 receptor - Shahul Hameed_2018_EMBO.Rep_19_e45619
Author(s) : Shahul Hameed UF , Haider I , Jamil M , Kountche BA , Guo X , Zarban RA , Kim D , Al-Babili S , Arold ST
Ref : EMBO Rep , : , 2018
Abstract :
PubMedSearch : Shahul Hameed_2018_EMBO.Rep_19_e45619
PubMedID: 30021834
Gene_locus related to this paper: strhe-ShHTL7

Title : Structural analysis of HTL and D14 proteins reveals the basis for ligand selectivity in Striga - Xu_2018_Nat.Commun_9_3947
Author(s) : Xu Y , Miyakawa T , Nosaki S , Nakamura A , Lyu Y , Nakamura H , Ohto U , Ishida H , Shimizu T , Asami T , Tanokura M
Ref : Nat Commun , 9 :3947 , 2018
Abstract :
PubMedSearch : Xu_2018_Nat.Commun_9_3947
PubMedID: 30258184
Gene_locus related to this paper: strhe-ShD14 , strhe-ShHTL4 , strhe-ShHTL1 , strhe-ShHTL7

Title : Structural analysis of HTL and D14 proteins reveals the basis for ligand selectivity in Striga - Xu_2018_Nat.Commun_9_3947
Author(s) : Xu Y , Miyakawa T , Nosaki S , Nakamura A , Lyu Y , Nakamura H , Ohto U , Ishida H , Shimizu T , Asami T , Tanokura M
Ref : Nat Commun , 9 :3947 , 2018
Abstract :
PubMedSearch : Xu_2018_Nat.Commun_9_3947
PubMedID: 30258184
Gene_locus related to this paper: strhe-ShD14 , strhe-ShHTL4 , strhe-ShHTL1 , strhe-ShHTL7

Title : Structural basis for specific inhibition of the highly sensitive ShHTL7 receptor - Shahul Hameed_2018_EMBO.Rep_19_e45619
Author(s) : Shahul Hameed UF , Haider I , Jamil M , Kountche BA , Guo X , Zarban RA , Kim D , Al-Babili S , Arold ST
Ref : EMBO Rep , : , 2018
Abstract :
PubMedSearch : Shahul Hameed_2018_EMBO.Rep_19_e45619
PubMedID: 30021834
Gene_locus related to this paper: strhe-ShHTL7

Title : Structural basis for specific inhibition of the highly sensitive ShHTL7 receptor - Shahul Hameed_2018_EMBO.Rep_19_e45619
Author(s) : Shahul Hameed UF , Haider I , Jamil M , Kountche BA , Guo X , Zarban RA , Kim D , Al-Babili S , Arold ST
Ref : EMBO Rep , : , 2018
Abstract :
PubMedSearch : Shahul Hameed_2018_EMBO.Rep_19_e45619
PubMedID: 30021834
Gene_locus related to this paper: strhe-ShHTL7

Title : ShHTL7 is a non-canonical receptor for strigolactones in root parasitic weeds -
Author(s) : Yao R , Wang F , Ming Z , Du X , Chen L , Wang Y , Zhang W , Deng H , Xie D
Ref : Cell Res , 27 :838 , 2017
PubMedID: 28059066
Gene_locus related to this paper: strhe-ShHTL7

Title : ShHTL7 is a non-canonical receptor for strigolactones in root parasitic weeds -
Author(s) : Yao R , Wang F , Ming Z , Du X , Chen L , Wang Y , Zhang W , Deng H , Xie D
Ref : Cell Res , 27 :838 , 2017
PubMedID: 28059066
Gene_locus related to this paper: strhe-ShHTL7

Title : ShHTL7 is a non-canonical receptor for strigolactones in root parasitic weeds -
Author(s) : Yao R , Wang F , Ming Z , Du X , Chen L , Wang Y , Zhang W , Deng H , Xie D
Ref : Cell Res , 27 :838 , 2017
PubMedID: 28059066
Gene_locus related to this paper: strhe-ShHTL7

Title : PARASITIC PLANTS. Probing strigolactone receptors in Striga hermonthica with fluorescence - Tsuchiya_2015_Science_349_864
Author(s) : Tsuchiya Y , Yoshimura M , Sato Y , Kuwata K , Toh S , Holbrook-Smith D , Zhang H , McCourt P , Itami K , Kinoshita T , Hagihara S
Ref : Science , 349 :864 , 2015
Abstract :
PubMedSearch : Tsuchiya_2015_Science_349_864
PubMedID: 26293962
Gene_locus related to this paper: strhe-ShHTL2 , strhe-ShHTL10 , strhe-ShHTL6 , strhe-ShHTL9 , strhe-ShHTL8 , strhe-ShHTL11 , strhe-ShD14 , strhe-ShHTL4 , strhe-ShHTL1 , strhe-ShHTL7 , strhe-ShHTL3 , strhe-ShHTL5

Title : Structure-function analysis identifies highly sensitive strigolactone receptors in Striga - Toh_2015_Science_350_203
Author(s) : Toh S , Holbrook-Smith D , Stogios PJ , Onopriyenko O , Lumba S , Tsuchiya Y , Savchenko A , McCourt P
Ref : Science , 350 :203 , 2015
Abstract :
PubMedSearch : Toh_2015_Science_350_203
PubMedID: 26450211
Gene_locus related to this paper: strhe-ShHTL2 , strhe-ShHTL10 , strhe-ShHTL6 , strhe-ShHTL9 , strhe-ShHTL8 , strhe-ShHTL11 , strhe-ShHTL4 , strhe-ShHTL1 , strhe-ShHTL7 , strhe-ShHTL3 , strhe-ShHTL5

Title : PARASITIC PLANTS. Probing strigolactone receptors in Striga hermonthica with fluorescence - Tsuchiya_2015_Science_349_864
Author(s) : Tsuchiya Y , Yoshimura M , Sato Y , Kuwata K , Toh S , Holbrook-Smith D , Zhang H , McCourt P , Itami K , Kinoshita T , Hagihara S
Ref : Science , 349 :864 , 2015
Abstract :
PubMedSearch : Tsuchiya_2015_Science_349_864
PubMedID: 26293962
Gene_locus related to this paper: strhe-ShHTL2 , strhe-ShHTL10 , strhe-ShHTL6 , strhe-ShHTL9 , strhe-ShHTL8 , strhe-ShHTL11 , strhe-ShD14 , strhe-ShHTL4 , strhe-ShHTL1 , strhe-ShHTL7 , strhe-ShHTL3 , strhe-ShHTL5

Title : Structure-function analysis identifies highly sensitive strigolactone receptors in Striga - Toh_2015_Science_350_203
Author(s) : Toh S , Holbrook-Smith D , Stogios PJ , Onopriyenko O , Lumba S , Tsuchiya Y , Savchenko A , McCourt P
Ref : Science , 350 :203 , 2015
Abstract :
PubMedSearch : Toh_2015_Science_350_203
PubMedID: 26450211
Gene_locus related to this paper: strhe-ShHTL2 , strhe-ShHTL10 , strhe-ShHTL6 , strhe-ShHTL9 , strhe-ShHTL8 , strhe-ShHTL11 , strhe-ShHTL4 , strhe-ShHTL1 , strhe-ShHTL7 , strhe-ShHTL3 , strhe-ShHTL5

Title : PARASITIC PLANTS. Probing strigolactone receptors in Striga hermonthica with fluorescence - Tsuchiya_2015_Science_349_864
Author(s) : Tsuchiya Y , Yoshimura M , Sato Y , Kuwata K , Toh S , Holbrook-Smith D , Zhang H , McCourt P , Itami K , Kinoshita T , Hagihara S
Ref : Science , 349 :864 , 2015
Abstract :
PubMedSearch : Tsuchiya_2015_Science_349_864
PubMedID: 26293962
Gene_locus related to this paper: strhe-ShHTL2 , strhe-ShHTL10 , strhe-ShHTL6 , strhe-ShHTL9 , strhe-ShHTL8 , strhe-ShHTL11 , strhe-ShD14 , strhe-ShHTL4 , strhe-ShHTL1 , strhe-ShHTL7 , strhe-ShHTL3 , strhe-ShHTL5

Title : Structure-function analysis identifies highly sensitive strigolactone receptors in Striga - Toh_2015_Science_350_203
Author(s) : Toh S , Holbrook-Smith D , Stogios PJ , Onopriyenko O , Lumba S , Tsuchiya Y , Savchenko A , McCourt P
Ref : Science , 350 :203 , 2015
Abstract :
PubMedSearch : Toh_2015_Science_350_203
PubMedID: 26450211
Gene_locus related to this paper: strhe-ShHTL2 , strhe-ShHTL10 , strhe-ShHTL6 , strhe-ShHTL9 , strhe-ShHTL8 , strhe-ShHTL11 , strhe-ShHTL4 , strhe-ShHTL1 , strhe-ShHTL7 , strhe-ShHTL3 , strhe-ShHTL5