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Paper Report for: Ikeda_2021_J.Med.Chem__

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Title: Design and Synthesis of Novel Spiro Derivatives as Potent and Reversible Monoacylglycerol Lipase (MAGL) Inhibitors: Bioisosteric Transformation from 3-Oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl Moiety
Ikeda S, Sugiyama H, Tokuhara H, Murakami M, Nakamura M, Oguro Y, Aida J, Morishita N, Sogabe S and Kamata M <9 more author(s)>
Ref: Journal of Medicinal Chemistry, :, 2021 : PubMed

        



Related information

Gene_Locus| human-MGLL
Structure in RCSB-PDB | 7L4W, 7L50, 7L4U, 7L4T
Structure in ESTHER | 7L4W, 7L50, 7L4U, 7L4T
Inhibitor | XP7-7L4U, SCHEMBL19421119, SCHEMBL19421059, SCHEMBL19834081,


Citations formats

Ikeda S, Sugiyama H, Tokuhara H, Murakami M, Nakamura M, Oguro Y, Aida J, Morishita N, Sogabe S, Dougan DR, Gay SC, Qin L, Arimura N, Takahashi Y, Sasaki M, Kamada Y, Aoyama K, Kimoto K, Kamata M (2021)
Design and Synthesis of Novel Spiro Derivatives as Potent and Reversible Monoacylglycerol Lipase (MAGL) Inhibitors: Bioisosteric Transformation from 3-Oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl Moiety
Journal of Medicinal Chemistry

Ikeda S, Sugiyama H, Tokuhara H, Murakami M, Nakamura M, Oguro Y, Aida J, Morishita N, Sogabe S, Dougan DR, Gay SC, Qin L, Arimura N, Takahashi Y, Sasaki M, Kamada Y, Aoyama K, Kimoto K, Kamata M (2021)
Journal of Medicinal Chemistry



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