K870
General
Type : Oxime, Bispyridinium
Chemical_Nomenclature :
Canonical SMILES : C1=C[N+](=CC=C1C(=O)N)CC=CC[N+]2=CC(=C(C(=C2)Cl)C=NO)Cl
InChI : InChI=1S\/C16H14Cl2N4O2\/c17-14-10-22(11-15(18)13(14)9-20-24)6-2-1-5-21-7-3-12(4-8-21)16(19)23\/h1-4,7-11H,5-6H2,(H-,19,23)\/p+2\/b2-1+
InChIKey : PDCFAKLOGXIFJN-OWOJBTEDSA-P
Other name(s) :
Target
Structure : No structure
Families : No family
References (3)
| Title : Novel chlorinated oxime K870 protects rats against paraoxon poisoning better than obidoxime - Maksimovic_2025_Drug.Chem.Toxicol__1 |
| Author(s) : Maksimovic z M , S TM , Dukanovic D , Mandic-Kovacevic N , Uletilovic S , Duran M , Kuca K , Musilek K , Loncar-Stojiljkovic D , Skrbic R , Stojiljkovic MP |
| Ref : Drug & Chemical Toxicology , :1 , 2025 |
| Abstract : |
| PubMedSearch : Maksimovic_2025_Drug.Chem.Toxicol__1 |
| PubMedID: 39871446 |
| Title : Toxicity, pharmacokinetics, and effectiveness of the ortho-chlorinated bispyridinium oxime, K870 - Karasova_2022_Food.Chem.Toxicol__113236 |
| Author(s) : Karasova JZ , Kassa J , Hepnarova V , Pejchal J , Junova L , Andrys R , Malinak D , Bzonek P , Kohoutova Z , Musilek K |
| Ref : Food & Chemical Toxicology , :113236 , 2022 |
| Abstract : |
| PubMedSearch : Karasova_2022_Food.Chem.Toxicol__113236 |
| PubMedID: 35738326 |
| Title : A Comparison of the Neuroprotective and Reactivating Efficacy of a Novel Bispyridinium Oxime K870 with Commonly Used Pralidoxime and the Oxime HI-6 in Tabun-Poisoned Rats - Kassa_2021_Acta.Medica.(Hradec.Kralove)_64_145 |
| Author(s) : Kassa J , Hatlapatkova J , Karasova JZ , Hepnarova V , Caisberger F , Pejchal J |
| Ref : Acta Medica (Hradec Kralove) , 64 :145 , 2021 |
| Abstract : |
| PubMedSearch : Kassa_2021_Acta.Medica.(Hradec.Kralove)_64_145 |
| PubMedID: 34779379 |