1K4Y
Name : Crystal Structure of Rabbit Liver Carboxylesterase in Complex with 4-piperidino-piperidine (leaving group of the hydrolysis of CPT11 to SN-38)
Revelation date : 01-May-2002
Family : Carb_B_Chordata
Gene_locus : rabit-1cxes
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Ligand : Inhibitor 4-piperidino-piperidine substrate Irinotecan Ligand in structure: Ligplot
References (3)
| Title : Structural insights into CPT-11 activation by mammalian carboxylesterases - Bencharit_2002_Nat.Struct.Biol_9_337 |
| Author(s) : Bencharit S , Morton CL , Howard-Williams EL , Danks MK , Potter PM , Redinbo MR |
| Ref : Nat Struct Biol , 9 :337 , 2002 |
| Abstract : |
| PubMedSearch : Bencharit_2002_Nat.Struct.Biol_9_337 |
| PubMedID: 11967565 |
| Gene_locus related to this paper: rabit-1cxes |
| Title : Structural insights into CPT-11 activation by mammalian carboxylesterases - Bencharit_2002_Nat.Struct.Biol_9_337 |
| Author(s) : Bencharit S , Morton CL , Howard-Williams EL , Danks MK , Potter PM , Redinbo MR |
| Ref : Nat Struct Biol , 9 :337 , 2002 |
| Abstract : |
| PubMedSearch : Bencharit_2002_Nat.Struct.Biol_9_337 |
| PubMedID: 11967565 |
| Gene_locus related to this paper: rabit-1cxes |
| Title : Structural insights into CPT-11 activation by mammalian carboxylesterases - Bencharit_2002_Nat.Struct.Biol_9_337 |
| Author(s) : Bencharit S , Morton CL , Howard-Williams EL , Danks MK , Potter PM , Redinbo MR |
| Ref : Nat Struct Biol , 9 :337 , 2002 |
| Abstract : |
| PubMedSearch : Bencharit_2002_Nat.Struct.Biol_9_337 |
| PubMedID: 11967565 |
| Gene_locus related to this paper: rabit-1cxes |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
Databases
PDB-Sum : 1K4Y Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP : 1K4Y Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP : 1K4Y Structural Classification Of Protein - SCOP server
PROTEOPEDIA : 1K4Y 3D, interactive encyclopedia of proteins - PROTEOPEDIA server