3O95

Name : Crystal Structure of Human DPP4 Bound to TAK-100

Revelation date : 26-Jan-2011

Family : DPP4N_Peptidase_S9

Gene_locus : human-DPP4

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Yano, J.K., Aertgeerts,K.

Ligand :

References (1)

Title : Discovery of a 3-pyridylacetic acid derivative (TAK-100) as a potent, selective and orally active dipeptidyl peptidase IV (DPP-4) inhibitor - Miyamoto_2011_J.Med.Chem_54_831
Author(s) : Miyamoto Y , Banno Y , Yamashita T , Fujimoto T , Oi S , Moritoh Y , Asakawa T , Kataoka O , Yashiro H , Takeuchi K , Suzuki N , Ikedo K , Kosaka T , Tsubotani S , Tani A , Sasaki M , Funami M , Amano M , Yamamoto Y , Aertgeerts K , Yano J , Maezaki H
Ref : Journal of Medicinal Chemistry , 54 :831 , 2011
PubMedID: 21218817
Gene_locus related to this paper: human-DPP4

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

Databases

PDB-Sum : 3O95 Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 3O95 Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 3O95 Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 3O95 3D, interactive encyclopedia of proteins - PROTEOPEDIA server