4G1F
Name : Crystal Structure of human Dipeptidyl Peptidase IV in complex with a pyridopyrimidinedione analogue
Revelation date : 27-Feb-2013
Family : DPP4N_Peptidase_S9
Gene_locus : human-DPP4
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Skene, R.J., Gwaltney, S.L.
Ligand : Inhibitor CHEMBL2159182 Ligand in structure: Ligplot
References (2)
| Title : Structure-based design of pyridopyrimidinediones as dipeptidyl peptidase IV inhibitors - Lam_2012_Bioorg.Med.Chem.Lett_22_6628 |
| Author(s) : Lam B , Zhang Z , Stafford JA , Skene RJ , Shi L , Gwaltney SL, 2nd |
| Ref : Bioorganic & Medicinal Chemistry Lett , 22 :6628 , 2012 |
| Abstract : |
| PubMedSearch : Lam_2012_Bioorg.Med.Chem.Lett_22_6628 |
| PubMedID: 23025999 |
| Gene_locus related to this paper: human-DPP4 |
| Title : Design and synthesis of pyrimidinone and pyrimidinedione inhibitors of dipeptidyl peptidase IV - Zhang_2011_J.Med.Chem_54_510 |
| Author(s) : Zhang Z , Wallace MB , Feng J , Stafford JA , Skene RJ , Shi L , Lee B , Aertgeerts K , Jennings A , Xu R , Kassel DB , Kaldor SW , Navre M , Webb DR , Gwaltney SL |
| Ref : Journal of Medicinal Chemistry , 54 :510 , 2011 |
| Abstract : |
| PubMedSearch : Zhang_2011_J.Med.Chem_54_510 |
| PubMedID: 21186796 |
| Gene_locus related to this paper: human-DPP4 |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
Databases
PDB-Sum : 4G1F Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP : 4G1F Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP : 4G1F Structural Classification Of Protein - SCOP server
PROTEOPEDIA : 4G1F 3D, interactive encyclopedia of proteins - PROTEOPEDIA server