Name : Human soluble epoxide hydrolase in complex with a cyclopropyl urea derivative

Revelation date : 08-Apr-2015

Family : Epoxide_hydrolase

Gene_locus : human-EPHX2

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Chiyo, N., Takai, K., Ishii, T.

Ligand : Inhibitor CHEMBL3114611 Ligand in structure: Ligplot

References (1)

Title : Three-dimensional rational approach to the discovery of potent substituted cyclopropyl urea soluble epoxide hydrolase inhibitors - Takai_2015_Bioorg.Med.Chem.Lett_25_1705
Author(s) : Takai K , Chiyo N , Nakajima T , Nariai T , Ishikawa C , Nakatani S , Ikeno A , Yamamoto S , Sone T
Ref : Bioorganic & Medicinal Chemistry Lett , 25 :1705 , 2015
Abstract :
PubMedSearch : Takai_2015_Bioorg.Med.Chem.Lett_25_1705
PubMedID: 25800114
Gene_locus related to this paper: human-EPHX2

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server


PDB-Sum : 4X6Y Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 4X6Y Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 4X6Y Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 4X6Y 3D, interactive encyclopedia of proteins - PROTEOPEDIA server