Name : Human soluble epoxide hydrolase in complex with a cyclopropyl urea derivative
Revelation date : 08-Apr-2015
Family : Epoxide_hydrolase
Gene_locus : human-EPHX2
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Chiyo, N., Takai, K., Ishii, T.
Ligand : Inhibitor CHEMBL3114611 Ligand in structure: Ligplot
Title : Three-dimensional rational approach to the discovery of potent substituted cyclopropyl urea soluble epoxide hydrolase inhibitors - Takai_2015_Bioorg.Med.Chem.Lett_25_1705 |
Author(s) : Takai K , Chiyo N , Nakajima T , Nariai T , Ishikawa C , Nakatani S , Ikeno A , Yamamoto S , Sone T |
Ref : Bioorganic & Medicinal Chemistry Lett , 25 :1705 , 2015 |
Abstract : |
PubMedSearch : Takai_2015_Bioorg.Med.Chem.Lett_25_1705 |
PubMedID: 25800114 |
Gene_locus related to this paper: human-EPHX2 |
PDB-Sum : 4X6Y Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP : 4X6Y Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP : 4X6Y Structural Classification Of Protein - SCOP server
PROTEOPEDIA : 4X6Y 3D, interactive encyclopedia of proteins - PROTEOPEDIA server