Name : Crystal structure of human soluble epoxide hydrolase complexed with trans-4-[4-(3-trifluoromethoxyphenyl-l-ureido)-cyclohexyloxy]-benzoic acid

Revelation date : 07-Feb-2018

Family : Epoxide_hydrolase

Gene_locus : human-EPHX2

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Kodani, S.D., Bahkta, S., Hwang, S.H., Pakhomova, S., Newcomer, M.E., Morisseau, C., Hammock, B.

Ligand : Inhibitor t-TUCB Ligand in structure: Ligplot

References (1)

Title : Identification and optimization of soluble epoxide hydrolase inhibitors with dual potency towards fatty acid amide hydrolase - Kodani_2018_Bioorg.Med.Chem.Lett_28_762
Author(s) : Kodani SD , Bhakta S , Hwang SH , Pakhomova S , Newcomer ME , Morisseau C , Hammock BD
Ref : Bioorganic & Medicinal Chemistry Lett , 28 :762 , 2018
Abstract :
PubMedSearch : Kodani_2018_Bioorg.Med.Chem.Lett_28_762
PubMedID: 29366648
Gene_locus related to this paper: human-EPHX2

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server


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FSSP : 6AUM Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 6AUM Structural Classification Of Protein - SCOP server

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