6TT0

Name : Crystal structure of Torpedo californica ACHE complexed with MC1420

Revelation date : 10-Jun-2020

Family : ACHE

Gene_locus : torca-ACHE

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Marco Catto, Leonardo Pisani, Eugenio De La Mora, Benny Danilo Belviso, Giuseppe Felice, Felice Mangiatordi, Andrea Pinto, Annalisa De Palma, Nunzio Denora, Rocco Caliandro, Jacques-Philippe Colletier, Israel Silman, Orazio Nicolotti, and Cosimo Damiano Altomare

Ligand : Inhibitor MC1420 Ligand in structure: Ligplot

References (1)

Title : Chiral Separation, X-ray Structure, and Biological Evaluation of a Potent and Reversible Dual Binding Site AChE Inhibitor - Catto_2020_ACS.Med.Chem.Lett_11_869
Author(s) : Catto M , Pisani L , De la Mora E , Belviso BD , Mangiatordi GF , Pinto A , Palma A , Denora N , Caliandro R , Colletier JP , Silman I , Nicolotti O , Altomare CD
Ref : ACS Med Chem Lett , 11 :869 , 2020
Abstract :
PubMedSearch : Catto_2020_ACS.Med.Chem.Lett_11_869
PubMedID: 32435398

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

Databases

PDB-Sum : 6TT0 Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 6TT0 Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 6TT0 Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 6TT0 3D, interactive encyclopedia of proteins - PROTEOPEDIA server