7A3J
Name : Crystal structure of DPP8 in complex with a 4-oxo-b-lactam based inhibitor A272
Revelation date : 30-Jun-2021
Family : DPP4N_Peptidase_S9
Gene_locus : human-DPP8
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Fehr, L., Carvalho, L.A.R., Ross, B.H., Lum, K., Vieira, A.C., Kiefersauer, R., Geiss-Friedlander, R., Kaiser, M., Rodrigues, T., Lucas, S.D., Cravatt, B.F., Huber, R., Moreira, R.
Ligand : Inhibitor 4-Oxo-beta-Lactam-A272, 4-Oxo-beta-Lactam-A272-closed Ligand in structure: Ligplot
References (1)
| Title : Chemoproteomics-Enabled Identification of 4-Oxo-beta-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9 - Carvalho_2022_Angew.Chem.Int.Ed.Engl_61_e202210498 |
| Author(s) : Carvalho LAR , Ross B , Fehr L , Bolgi O , Wohrle S , Lum KM , Podlesainski D , Vieira AC , Kiefersauer R , Felix R , Rodrigues T , Lucas SD , Gross O , Geiss-Friedlander R , Cravatt BF , Huber R , Kaiser M , Moreira R |
| Ref : Angew Chem Int Ed Engl , : , 2022 |
| Abstract : |
| PubMedSearch : Carvalho_2022_Angew.Chem.Int.Ed.Engl_61_e202210498 |
| PubMedID: 36089535 |
| Gene_locus related to this paper: human-DPP8 , human-DPP9 |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
Databases
PDB-Sum : 7A3J Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP : 7A3J Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP : 7A3J Structural Classification Of Protein - SCOP server
PROTEOPEDIA : 7A3J 3D, interactive encyclopedia of proteins - PROTEOPEDIA server