7B3P
Name : Human Notum in complex with ARUK3003775
Revelation date : 08-Dec-2021
Family : Pectinacetylesterase-Notum
Gene_locus : human-NOTUM
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Zhao, Y.,Jones, E.Y.,Fish, P.
Ligand : Inhibitor ARUK3003775 Ligand in structure: Ligplot
References (1)
| Title : Virtual Screening Directly Identifies New Fragment-Sized Inhibitors of Carboxylesterase Notum with Nanomolar Activity - Steadman_2022_J.Med.Chem_65_562 |
| Author(s) : Steadman D , Atkinson BN , Zhao Y , Willis NJ , Frew S , Monaghan A , Patel C , Armstrong E , Costelloe K , Magno L , Bictash M , Jones EY , Fish PV , Svensson F |
| Ref : Journal of Medicinal Chemistry , 65 :562 , 2022 |
| Abstract : |
| PubMedSearch : Steadman_2022_J.Med.Chem_65_562 |
| PubMedID: 34939789 |
| Gene_locus related to this paper: human-NOTUM |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
Databases
PDB-Sum : 7B3P Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP : 7B3P Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP : 7B3P Structural Classification Of Protein - SCOP server
PROTEOPEDIA : 7B3P 3D, interactive encyclopedia of proteins - PROTEOPEDIA server