7B3X

Name : Human Notum in complex with ARUK3003748

Revelation date : 08-Dec-2021

Family : Pectinacetylesterase-Notum

Gene_locus : human-NOTUM

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Fish, P.,Jones, E.Y.

Ligand :

References (1)

Title : Virtual Screening Directly Identifies New Fragment-Sized Inhibitors of Carboxylesterase Notum with Nanomolar Activity - Steadman_2022_J.Med.Chem_65_562
Author(s) : Steadman D , Atkinson BN , Zhao Y , Willis NJ , Frew S , Monaghan A , Patel C , Armstrong E , Costelloe K , Magno L , Bictash M , Jones EY , Fish PV , Svensson F
Ref : Journal of Medicinal Chemistry , 65 :562 , 2022
PubMedID: 34939789
Gene_locus related to this paper: human-NOTUM

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

Databases

PDB-Sum : 7B3X Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 7B3X Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 7B3X Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 7B3X 3D, interactive encyclopedia of proteins - PROTEOPEDIA server