7B8C
Name : Structure of the human Wnt deacylase Notum in complex with fragment 147
Revelation date : 12-Jan-2022
Family : Pectinacetylesterase-Notum
Gene_locus : human-NOTUM
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Zhao, Y.,Jones, E.Y.
Ligand : Inhibitor Fragment-147 Ligand in structure: Ligplot
References (1)
| Title : Structural Analysis and Development of Notum Fragment Screening Hits - Zhao_2022_ACS.Chem.Neurosci_13_2060 |
| Author(s) : Zhao Y , Mahy W , Willis NJ , Woodward HL , Steadman D , Bayle ED , Atkinson BN , Sipthorp J , Vecchia L , Ruza RR , Harlos K , Jeganathan F , Constantinou S , Costa A , Kjaer S , Bictash M , Salinas PC , Whiting P , Vincent JP , Fish PV , Jones EY |
| Ref : ACS Chem Neurosci , 13 :2060 , 2022 |
| Abstract : |
| PubMedSearch : Zhao_2022_ACS.Chem.Neurosci_13_2060 |
| PubMedID: 35731924 |
| Gene_locus related to this paper: human-NOTUM |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
Databases
PDB-Sum : 7B8C Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP : 7B8C Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP : 7B8C Structural Classification Of Protein - SCOP server
PROTEOPEDIA : 7B8C 3D, interactive encyclopedia of proteins - PROTEOPEDIA server