Name : Mus musculus Acetylcholinesterase in complex with 7-[(1-benzylpiperidin-3-yl)methoxy]-3,4-dimethyl-2H-chromen-2-one multitargeting inhibitor of AChE and MAO

Revelation date : 06-Apr-2022

Family : ACHE

Gene_locus : mouse-ACHE

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Fredrik Ekstrom, Andrea Gottinger, Nina Forsgren, Marco Catto, Luca G. Iacovino, Leonardo Pisani, and Claudia Binda

Ligand : Inhibitor 7QB4-Cpd2 Ligand in structure: Ligplot

References (1)

Title : Dual Reversible Coumarin Inhibitors Mutually Bound to Monoamine Oxidase B and Acetylcholinesterase Crystal Structures - Ekstrom_2022_ACS.Med.Chem.Lett_13_499
Author(s) : Ekstrom F , Gottinger A , Forsgren N , Catto M , Iacovino LG , Pisani P , Binda C
Ref : ACS Med Chem Lett , 13 :499 , 2022
Abstract :
PubMedSearch : Ekstrom_2022_ACS.Med.Chem.Lett_13_499
PubMedID: 35300078
Gene_locus related to this paper: mouse-ACHE

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server


PDB-Sum : 7QB4 Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 7QB4 Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 7QB4 Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 7QB4 3D, interactive encyclopedia of proteins - PROTEOPEDIA server